Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10571); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5106) Bacteria (10) Eukaryota (5092) unclassified (4) Structure (17) Characterized (84)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 51 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CBH1 (fragment)   Galeropsis sp. specimenB AEO14758.1    
 CBH1 (fragment)   Galeropsis sp. specimenB AEO14785.1    
 CBH1 (fragment)   Ganoderma sp. E CFW-2011 DSMZ62950 AEN99788.1    
 CBH1 (fragment)   Ganoderma sp. specimenE AEO14767.1    
 CBH1 (fragment)   Ganoderma sp. specimenE AEO14768.1    
 CBH1   Geotrichum candidum 3C AIO10971.1   4ZZT[A]
4ZZU[A]
4ZZV[A]
4ZZW[A]
5AMP[A]
 CBH1 (fragment)   Hebeloma sp. pajaritoNM AEO14770.1    
 cellobiohydrolase 1 (HirCel7A;38802) (Cel7A) 3.2.1.176 Heterobasidion irregulare TC 32-1     2XSP[A]
2YG1[A,B]
 endoglucanase 3 (HmEG3) (fragment) 3.2.1.4 Holomastigotoides mirabile BAB64565.1 Q95P29  
 endoglucanase 2 (HmEG2) 3.2.1.4 Holomastigotoides mirabile BAB64564.1 Q95P30  
 endoglucanase 1 (HmEG1) 3.2.1.4 Holomastigotoides mirabile BAB64563.1 Q95P31  
 cellobiohydrolase I (Cbh1.1;Cbh1;Cbh-1;HgCbh1) (Cel7A) 3.2.1.176 Humicola grisea var. thermoidea CAA35159.1 P15828  
 endo-β-1,4-glucanase I (Egl1;EG-I) 3.2.1.4 Humicola grisea var. thermoidea BAA09786.1 Q12622  
 cellobiohydrolase I.2 (Cbh1.2) 3.2.1.176 Humicola grisea var. thermoidea AAD31545.1
AAD11942.1
AAN19007.1
O94093
Q7LV60
 
 cellobiohydrolase I (Exo1) 3.2.1.176 Humicola grisea var. thermoidea IFO9854 BAA74517.1 O93780  
 cellobiohydrolase (Cbh-1;HgtCel7A) (Cel7A) 3.2.1.176 Humicola grisea var. thermoidea IFO9854 / CBS 225.63 BAA09785.1 Q12621 4CSI[A,B]
 endoglucanase I (EG I;EG1) (Cel7B) 3.2.1.4 Humicola insolens AAE25068.1
AAE25070.1
P56680 1A39[A]
1DYM[A]
1OJI[A]
1OJJ[A,B]
1OJK[A,B]
2A39[A,B]
 CbhI (fragment)   Hymenoscyphus sp. MK171 CCF3784 CBX31948.1 E3Q0D3  
 cellobiohydrolase I (CbhI)   Hypocrea orientalis EU7-22 AFD50192.1    
 endoglucanase I (EgI)   Hypocrea orientalis EU7-22 AFD50194.1    
 CBHI (fragment)   Infundibulicybe gibba ABY61330.1
ABY61331.1
ABY61332.1
ABY61333.1
ABY61334.1
B0FQ49  
 CBHI (fragment)   Infundibulicybe gibba ABY61335.1 B0FQ54  
 CBHI (fragment)   Infundibulicybe gibba ABY61336.1 B0FQ55  
 CBHI (fragment)   Infundibulicybe gibba ABY61337.1
ABY61338.1
B0FQ56  
 CBHI (fragment)   Infundibulicybe gibba ABY61341.1 B0FQ60  
 CBHI (fragment)   Infundibulicybe gibba ABY61342.1 B0FQ61  
 CBHI (fragment)   Infundibulicybe gibba ABY61343.1 B0FQ62  
 CBHI (fragment)   Infundibulicybe gibba 1c ABY61339.1 B0FQ58  
 CBHI (fragment)   Infundibulicybe gibba 1d ABY61340.1 B0FQ59  
 cellobiohydrolase (Cex1)   Irpex lacteus MC-2 BAD16575.1 Q75NB5  
 exo-cellulase (Cel1;Ex-1) 3.2.1.176 Irpex lacteus MC-2 BAA76363.1 Q9Y722  
 cellobiohydrolase II (Cel2;Ex-2) 3.2.1.176 Irpex lacteus MC-2 BAA76364.1 Q9Y723  
 exo-cellulase (Cel3)   Irpex lacteus MC-2 BAA76365.1 Q9Y724  
 unnamed protein product   Lasiodiplodia theobromae CAD79786.1    
 cellulase (Cel7A)   Lentinula edodes STAMETS CS-2 AAK95563.1 Q96VU3  
 Cbh1 (fragment)   Lentinus sajor-caju MG04 AFJ04531.1    
 CBH1 (fragment)   Leptodontidium elatius CCF3045 ADY89574.1    
 CBH1 (fragment)   Leptodontidium elatius CCF3045 ADY89587.1    
 cellulase (Cel2)   Leptosphaeria maculans AAF70171.1 Q9P8K7  
 cellulase (Cel1)   Leptosphaeria maculans AAF70170.1 Q9P8K8  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX90163.1 E4ZFU3  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX94030.1 E4ZQM5  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY00240.1 E5A999  
 CBH1 (fragment)   Leptosphaeria sp. mg157 AEO14755.1    
 CBH1 (fragment)   Leptosphaeria sp. mg157 AEO14800.1    
 CBH1 (fragment)   Leptosphaeria sp. mg157 USDA54026 AEN99782.1    
 cellobiohydrolase I-I (Cel7A)   Leucoagaricus gongylophorus Ae322 CDJ79819.1    
 cellobiohydrolase I-II (Cel7B)   Leucoagaricus gongylophorus Ae322 CDJ79820.1    
 CBH1 (fragment)   Limacella glischra DSMZ62950 AEN92167.1    
 CBH1 (fragment)   Limacella glischra DSMZ62950 AEN92168.1    
 CBH1 (fragment)   Limacella illinita 1 AEO14773.1    
 CBH1 (fragment)   Limacella illinita DSMZ62950 AEN92169.1    
 CBH1 (fragment)   Limacella illinita DSMZ62950 AEN92170.1    
 CBH1 (fragment)   Limacella illinita DSMZ62950 AEN92171.1    
 CBH1 (fragment)   Limacella illinita DSMZ62950 AEN92196.1    
 GH7A   Limnoria quadripunctata ADB85437.1 D4HRK9  
 cellobiohydrolase (GH7B;LqCel7B) (Cel7B) 3.2.1.176 Limnoria quadripunctata ADB85438.1 D4HRL0 4GWA[A,B]
4HAP[A,B]
4HAQ[A,B]
4IPM[A]
 GH7C   Limnoria quadripunctata ADB85439.1 D4HRL1  
 dCel2   Lingulodinium polyedrum ADG63074.1 D8UXL7  
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50312.1    
 cellobiohydrolase, partial (CbhI) (fragment)   Lophodermium sp. ZY-2014 AIJ50323.1    
 cellobiohydrolase, partial (CbhI) (fragment)   Lophodermium sp. ZY-2014 AIJ50325.1    
 cellobiohydrolase, partial (CbhI) (fragment)   Lophodermium sp. ZY-2014 AIJ50336.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50305.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50306.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50307.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50308.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50309.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50310.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50311.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50313.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50314.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50315.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50316.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50317.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50318.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50319.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50320.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50321.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50322.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50324.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50326.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50327.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50328.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50329.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50330.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50331.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50332.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50333.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50334.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50335.1    
 CBH1 (fragment)   Lophodermium sp. ZY-2014 AIJ50337.1    
 CBH1 (fragment)   Lycoperdon sp. specimenIL AEO14775.1    
 CBH1 (fragment)   Lycoperdon sp. specimenIL AEO14777.1    
 cellobiohydrolase, partial   Macrotermes gilvus AKV16370.1    
 MG06834.4   Magnaporthe oryzae 70-15 XP_370337.1 G4MMG0  
 MG07809.4   Magnaporthe oryzae 70-15 XP_003713026.1
XP_367905.1
   
 MG06663.4   Magnaporthe oryzae 70-15 XP_370166.1    
 cellobiohydrolase (MG10712.4) (Cel7A) 3.2.1.176 Magnaporthe oryzae 70-15 XP_367082.1 G4NIA4  
 endo-β-1,3/1,4-glucanase / endotransglucosylase (Egl1;ETG;MoCel7B;MGG_02532;MG02532.4) (Cel7B)   Magnaporthe oryzae 70-15 XP_003721274.1
AEX97159.1
XP_366456.1
XP_366456.2
   
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