Glycoside Hydrolase Family 7

Activities in Familyendo-β-1,4-glucanase (EC 3.2.1.4); reducing end-acting cellobiohydrolase (EC 3.2.1.176); chitosanase (EC 3.2.1.132); endo-β-1,3-1,4-glucanase (EC 3.2.1.73)
Mechanism Retaining
ClanGH-B
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family C. The cellobiohydrolases of this family act processively from the reducing ends of cellulose chains to generate cellobiose. This is markedly different from the IUBMB definition of cellobiohydrolases (EC 3.2.1.91), which act from the non-reducing ends of cellulose.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (10567); Uniprot accession (528); PDB accession (84); 3D entries (17); cryst (0)
All (5102) Bacteria (10) Eukaryota (5088) unclassified (4) Structure (17) Characterized (84)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 51 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CBH1 (fragment)   Chaetomium globosum DSMZ1909 AEO14798.1    
 glycoside hydrolase family 7 protein   Chaetomium gracile AGV05132.1    
 cellobiohydrolase I (Cbh1)   Chaetomium murorum AGU16947.1    
 GH7 (fragment)   Chaetomium senegalense CBS 728.84 CDF76452.1    
 CBH1 (fragment)   Chaetomium sp. mg128 AEO14751.1    
 CBH1 (fragment)   Chaetomium sp. mg128 DSMZ1004 AEN99786.1    
 glycoside hydrolase family 7 protein (fragment)   Chaetomium strumarium AGV05129.1    
 unnamed protein product   Chaetomium thermophilum CAD79779.1    
 cellobiohydrolase (Cbh1;CtCbh1) (Cel7A) 3.2.1.176 Chaetomium thermophilum ALKO4265 CAM98448.1 A7WNU1  
 cellobiohydrolase (Cbh1;EG7-1) (Cel7A) 3.2.1.176 Chaetomium thermophilum CT2 AAW64926.1
AGY80096.1
Q5G2D5  
 cellobiohydrolase (Cbh3) 3.2.1.176 Chaetomium thermophilum CT2 AAY89412.2
ABN13116.1
Q4JI68  
 Eg7-2 (fragment)   Chaetomium thermophilum CT2 AGY80097.1    
 Cbh7-4   Chaetomium thermophilum CT2 AGY80098.1    
 CBHI (fragment)   Chaetomium thermophilum var. thermophilum DSM1495 AAT84320.1 Q692I2  
 glycoside hydrolase family 7 protein (fragment)   Chaetomium virescens AGV05124.1    
 CbhI (fragment)   Chalara longipes ZK47/08 CBX31949.1 E3Q0D4  
 CbhI (fragment)   Chalara longipes ZK47/08 CBX31950.1 E3Q0D5  
 CbhI (fragment)   Chalara longipes ZK47/08 CBX31951.1 E3Q0D6  
 CBH1 (fragment)   Chalara longipes ZK47/08 ADY89582.1    
 GH7A   Chelura terebrans AGM37865.1    
 Gh7D   Chelura terebrans AGM37866.1    
 CBH1 (fragment)   Chloridium virescens CCF1782 ADY89576.1
AEQ59473.1
   
 CBH1 (fragment)   Chloridium virescens CCF1787 ADY89575.1    
 CBH1 (fragment)   Chloridium virescens CCF1787 ADY89594.1    
 CBHI (fragment)   Chlorophyllum molybdites ABY61349.1 B0FQ68  
 CBHI (fragment)   Chlorophyllum molybdites ABY61350.1 B0FQ69  
 CBHI (fragment)   Chlorophyllum molybdites ABY61351.1 B0FQ70  
 CBHI (fragment)   Chlorophyllum molybdites ABY61352.1 B0FQ71  
 CBHI (fragment)   Chlorophyllum molybdites ABY61353.1 B0FQ72  
 CBHI (fragment)   Chlorophyllum molybdites ABY61354.1 B0FQ73  
 cellobiohydrolase Ia (Cbh1a;CBH Ia) (Cel7A) 3.2.1.176 Chrysosporium lucknowense AAQ38146.1
ACH15004.1
ACH15013.1
   
 cellobiohydrolase I (Cel1) 3.2.1.176 Claviceps purpurea T5 CAA68840.1 O00082  
 CBHI (fragment)   Clitocybe nuda ABY61344.1 B0FQ63  
 CBHI (fragment)   Clitocybe nuda ABY61345.1 B0FQ64  
 CBHI (fragment)   Clitocybe nuda ABY61346.1 B0FQ65  
 CBHI (fragment)   Clitocybe nuda ABY61347.1 B0FQ66  
 CBHI (fragment)   Clitocybe nuda ABY61348.1 B0FQ67  
 CBHI (fragment)   Clitopilus prunulus ABY61327.1
ABY61328.1
ABY61329.1
B0FQ46  
 CBH1 (fragment)   Clonostachys rosea DSMZ1165 AEO14760.1    
 cellulase (Cel7A)   Coniophora puteana WD-758 BAH59084.1 C4B8I3  
 cellulase (Cel7B)   Coniophora puteana WD-758 BAH59085.1 C4B8I4  
 unnamed protein product   Coprinopsis cinerea CAD79793.1    
 CBH1 (fragment)   Coprinopsis cinerea AEO14794.1    
 CBH1 (fragment)   Coprinopsis cinerea DSMZ1004 AEN99785.1    
 CBH1 (fragment)   Coprinus sp. specimenIL AEO14774.1    
 ORF (fragment)   Coptotermes formosanus AGM32260.1    
 ORF (fragment)   Coptotermes formosanus AGM32530.1    
 endo-β-1,4-glucanase (CLhgEG1) 3.2.1.4 Coptotermes lacteus symbiont WH2002 BAC07551.1 Q8MXY2  
 endo-β-1,4-glucanase (CLhgEG2) 3.2.1.4 Coptotermes lacteus symbiont WH2002 BAC07552.1 Q8MXY1  
 glycoside hydrolase family 7 protein   Corynascus sepedonium AGV05125.1    
 GH7 (fragment)   Crassicarpon thermophilum CBS 406.69 CDF76453.1    
 cellobiohydrolase I (Cbh-1;Cbh7A)   Cryphonectria parasitica EP155 AAB00479.1 Q00548  
 CBH1 (fragment)   Cyathus stercoreus AEO14754.1    
 CBH1 (fragment)   Cyathus stercoreus AEO14778.1    
 CBH1 (fragment)   Cyathus stercoreus AEO14783.1    
 CBH1 (fragment)   Cyathus stercoreus AEO14784.1    
 cellobiohydrolase (CBHI;DAPPUDRAFT_347598) (Cel7A)   Daphnia pulex EFX85218.1   4XNN[A,B]
5MCC[A,B]
5MCD[A,B]
5MCE[A,B]
5MCF[A,B]
5MCH[A,B]
5MCI[A,B]
5MCJ[A,B]
5MCK[A,B]
5MCL[A,B]
5MCM[A,B]
5MCN[A,B]
 cellobiohydrolase I (CBH1;Cel7) (Cel7B) 3.2.1.176 Dichomitus squalens FBCC312 CDJ79665.1    
 cellobiohydrolase I (CbhA;DdiCel7A;DDB_G0268446) (Cel7A) 3.2.1.176 Dictyostelium discoideum AX4 EAL73676.1   4ZZQ[A]
 cellobiohydrolase (DpuCel7A;DICPUDRAFT_151874) 3.2.1.176 Dictyostelium purpureum QSDP1 EGC35742.1   4ZZP[A,B]
 CBH1 (fragment)   Epicoccum nigrum USDA54026 AEN99781.1    
 unnamed protein product   Exidia glandulosa CAD79790.1    
 unnamed protein product   Exidia glandulosa CAD79791.1    
 cellobiohydrolase (FvCel7B) (Cel7B) 3.2.1.176 Flammulina velutipes Fv-1 BAJ07535.1 D5MSJ4  
 cellobiohydrolase (FvCel7A) (Cel7A) 3.2.1.176 Flammulina velutipes Fv-1 BAJ07534.1 D5MSJ3  
 ORF   Flammulina velutipes KACC 42777 ADX07301.1    
 exoglucanase type C (CBH-C)   Fusarium avenaceum AAS82857.1 Q5MY20  
 Cbh-C (fragment)   Fusarium avenaceum 12 AAN07161.1 Q8J144  
 cellobiohydrolase-c (fragment)   Fusarium chlamydosporum ABY16677.1 A9YG24  
 cellobiohydrolase-c (fragment)   Fusarium culmorum ABY16674.1 A9YG21  
 FFUJ_01096   Fusarium fujikuroi IMI 58289 CCT62360.1    
 FFUJ_06426   Fusarium fujikuroi IMI 58289 CCT70451.1    
 FFUJ_11746   Fusarium fujikuroi IMI 58289 CCT75711.1    
 Cbh-C (fragment)   Fusarium graminearum 3 AAN07152.1 Q8J097  
 Cbh-C (fragment)   Fusarium graminearum 4 AAN07153.1 Q8J097  
 Cbh-C (fragment)   Fusarium graminearum 9 AAN07158.1 Q8J097  
 cellobiohydrolase C (Cel7) (Cel7A)   Fusarium graminearum K59 AAO42612.2
AAO42612.1
AAR02398.1
AAX60002.1
Q6XZE4  
 unnamed protein product   Fusarium graminearum PH-1 CEF72527.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF76543.1    
 Cbh-C (fragment)   Fusarium lateritium CBS 73774 AAP31849.1 Q6K0L5  
 cellobiohydrolase I (Cel7A)   Fusarium oxysporum AAA65587.1
AAA93710.1
AAC10999.1
ABY16672.1
P46238  
 endo-β-1,4-glucanase I (EG I;Eg1;Fof7) (Cel7B) 3.2.1.4 Fusarium oxysporum AAA65586.1
AAE25069.1
AAG09047.1
P46237 1OVW[A,B,C,D]
2OVW[A,B,C,D]
3OVW[A,B]
4OVW[A,B]
 Cbh-C (fragment)   Fusarium oxysporum f. sp. melonis AAQ12003.1 Q716Y5  
 CBH1 (fragment)   Fusarium poae AEO14753.1    
 exoglucanase type C (Cbh-C)   Fusarium poae AAX60003.1
AAQ11999.1
Q3ZNL7  
 cellobiohydrolase-c (fragment)   Fusarium proliferatum ABY16676.1 A9YG23  
 Cbh-C (fragment)   Fusarium sambucinum 10 AAN07159.1 Q8J145  
 Cbh-C (fragment)   Fusarium sambucinum 11 AAN07160.1 Q8J076  
 exoglucanase type C (CBH-C)   Fusarium sambucinum 2 AAS82858.1
AAN07151.1
AAX60000.1
ABY16678.1
Q5MY19  
 Cbh-C (fragment)   Fusarium sambucinum 6 AAN07155.1 Q8J076  
 Cbh-C (fragment)   Fusarium sambucinum 8 AAN07157.1 Q8J076  
 Cbh-C (fragment)   Fusarium sp. F1 AAN07150.1 Q8J149  
 Cbh-C (fragment)   Fusarium sporotrichioides AAQ12001.1 Q716Y7  
 Cbh-C (fragment)   Fusarium tricinctum 7 AAN07156.1 Q8J146  
 cellobiohydrolase-c (fragment)   Fusarium udum ABY16673.1 A9YG20  
 exoglucanase type C (Cbh-C)   Fusarium venenatum 5 AAX60001.1
AAN07154.1
Q3ZNL9  
 cellobiohydrolase-c (fragment)   Fusarium verticillioides ABY16675.1 A9YG22  
 Cbh-C (fragment)   Fusarium verticillioides AAQ12000.1    
 cellobiohydrolase I (CbhI) 3.2.1.176 Fusicoccum sp. BCC4124 ABS82449.1 A7LN91  
 CBH1 (fragment)   Galeropsis sp. specimenB AEO14756.1    
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