Activities in Family	Peptidoglycan endo-β-1,4-N-acetylglucosaminidase (EC 3.2.1.-); Mannosyl-glycoprotein endo-β-N-acetylglucosaminidase (EC 3.2.1.96);
Mechanism	Unknown e
3D Structure Status	lysozyme fold
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Glu
Note	The 3-D structure of Sphingomonas sp. strain A1 FlgJ protein of this family has recently been solved (Hashimotoa et al., BBRC 2009); there is only one, unconfirmed, report of b-1,4-N-acetylmuramoylhydrolase (EC 3.2.1.17) activity
External resources	CAZypedia;
Statistics	GenBank accession (38994); Uniprot accession (31); PDB accession (25); 3D entries (14); cryst (0)

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Viruses
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
ORF		Dubowvirus dv11	AAL82277.1 NP_803302.1
ORF004		Dubowvirus dv53	AAX90835.1
ORF004		Dubowvirus dv69	AAX90759.1
lyz		Dubowvirus dv80alpha	ABF71638.1
ORF004		Dubowvirus dv85	AAX90914.1
cell wall hydrolase		Dubowvirus ETA2 TY94	BAF43879.1
gp58		Dubowvirus IPLA88	ACJ64586.1
Orf64		Dubowvirus MR25	BAG48161.1
cell wall hydrolase		Dubowvirus NM1	ABF73090.1
cell wall hydrolase		Dubowvirus NM2	ABF73156.1
Orf22		Dubowvirus SAP26	ADL66953.1
ORF		Enterococcus phage EF1	ASZ76815.1
ORF		Enterococcus phage EF5	ASZ77376.1
H1_49		Enterococcus phage H1	UYE92469.1
PHIEF11_0028		Enterococcus phage phiEf11	ACV83371.1
endolysin, N-acetylglucosaminidase domain		Faecalibacterium phage FP_Epona	AUV56483.1
ORF		Flavobacterium phage FL-1	APZ82885.1
immuto136C_35		Flavobacterium phage vB_FspM_immuto_13-6C	QQO92191.1
immuto26A_35		Flavobacterium phage vB_FspM_immuto_2-6A	QQO91714.1
immuto35A_35		Flavobacterium phage vB_FspM_immuto_3-5A	QQO91953.1
tant81_gp060		Flavobacterium phage vB_FspS_tant8-1	QHB40991.1
ORF		Listeria phage 20422-1	WWO59043.1
ORF		Listeria phage 805405-1	WWO59228.1
CKA15_116		Listeria phage cka15	WIW77327.1
ORF		Listeria phage List-36	AIA64248.1
ORF		Listeria phage LMSP-25	AIA64463.1
ORF		Listeria phage LMTA-148	AID17379.1
ORF		Listeria phage LMTA-34	AID17021.1
ORF		Listeria phage LMTA-34	AII27328.1
ORF (fragment)		Listeria phage LMTA-57	AID17574.1
ORF		Listeria phage LMTA-94	AID17179.1
FK485_0074		Listeria phage LP-039	QEP53074.1 QEP53094.2
LP048_096		Listeria phage LP-048	AHL19769.1
LP064_113		Listeria phage LP-064	AHL19135.1
FK486_0041		Listeria phage LP-066	QDK04888.1 QDK04943.2
LP083-2_111		Listeria phage LP-083-2	AHL19318.1
LP124_032		Listeria phage LP-124	AHL19429.1
LP125_106		Listeria phage LP-125	AGI11431.1
HUK29_0094		Listeria phage LP-Mix_6.1	QNL31861.1
HUK30_0097		Listeria phage LP-Mix_6.2	QNL32059.1
tape measure protein		Listeria phage P100plus	QJB22284.1
tape measure protein		Listeria phage P200	QJB22474.1
vBLinoVEfB7_102		Listeria phage vB_Lino_VEfB7	QIG60845.1
vBLivaVAfA18_109		Listeria phage vB_Liva_VAfA18	QIG61033.1
AG2_089		Listeria phage vB_LmoM_AG20	AFJ76025.1
ORF		Listeria phage WIL-1	AIM49855.1
ORF		Listeria virus P61	QKN84301.1
phiG2_21		Lysinibacillus phage phiG2	WID10864.1
phiG2_24		Lysinibacillus phage phiG2	WID10867.1
M3_0009		Lysinibacillus phage vB_LfM_LysYB1	WAB24960.1
M5_0070		Lysinibacillus phage vB_LfM_LysYB2	WAB25248.1
ORF		Myoviridae sp.	QHJ84562.1
flagellar protein		Myoviridae sp.	QMP83601.1
glucosaminidase domain-containing protein		Paenibacillus phage Pd_22F	QVQ56262.1
N-acetylmuramoyl-L-alanine amidase		Paenibacillus phage Pd_22F	QVQ56199.1
gp26		Pecentumvirus A511	AAY52878.1
gp28		Pecentumvirus P100	AAY53331.1
ORF		Pelagibacter phage HTVC008M	AGE60521.1
P109_gp53 (fragment)		Pelagibacter phage HTVC109P	AXN54118.1
HTVC115P_gp20		Pelagibacter phage HTVC115P	QGZ18255.1
Mosig_00158		Pelagibacter phage Mosig EXVC030M	QOI69119.1
CDIF1296T_phi043		Peptoclostridium phage phiCDIF1296T DSM 1296	AKP44717.1
lysin		Phietavirus B122	AZU99194.1
ORF61		Phietavirus ETA	BAA97647.1 NP_510955.1
cell wall hydrolase		Phietavirus ETA3 TY32	BAF43947.1
ORF003		Phietavirus EW	AAX91343.1
tail tip protein (P61)		Phietavirus MR11	BAF79638.1 BAF95154.1
cell wall hydrolase		Phietavirus NM4	ABF73289.1
Ply187		Phietavirus pv187	CAA69022.1 AAX90680.1
ORF004		Phietavirus pv29	AAX91723.1
ORF004		Phietavirus pv37	AAX91267.1
ORF004		Phietavirus pv52a	AAX91798.1
ORF004		Phietavirus pv55	AAX91646.1
ORF004		Phietavirus pv71	AAX91574.1
SA80_55		Phietavirus pv80	ABJ88902.1
ORF004		Phietavirus pv88	AAX91863.1
ORF004		Phietavirus pv92	AAX91935.1
ORF004		Phietavirus pv96	AAX91421.1
ORF005		Phietavirus X2	AAX92010.1
P5		Red mite associated cystovirus	UQT02516.1
EVB56_084 (fragment)		Rhizobium phage RHph_Y1_10	QIG68275.1
cn25		Rockefellervirus CNPH82	ABI15702.1
IPLA5_0025		Rockefellervirus IPLA5	AFM73728.1
IPLA7_0022		Rockefellervirus IPLA7	AFM73792.1
Remus_106		Silviavirus remus	QVD58737.1
ORF		Silviavirus SA11	AFO70717.1
N-acetylmuramoyl-L-alanine amidase		Siphoviridae sp.	UOF77033.1
110_00032		Staphylococcus phage 110	WJJ58196.1
lysin N-acetylmuramoyl-L-alanine amidase		Staphylococcus phage 2339	WVQ00987.1
cell wall hydrolase		Staphylococcus phage 3MRA	AIB56188.1
Phi456_00009		Staphylococcus phage 456	QLF86440.1
lysin		Staphylococcus phage 55-2	AKO62029.1
lysin		Staphylococcus phage 55-3	AKO62094.1
lysin N-acetylmuramoyl-L-alanine amidase		Staphylococcus phage 6199	WVQ01052.1
lysin N-acetylmuramoyl-L-alanine amidase		Staphylococcus phage 7094	WVQ01121.1
lysin N-acetylmuramoyl-L-alanine amidase		Staphylococcus phage 7206	WVQ01193.1
80A_00031		Staphylococcus phage 80A	WJJ57810.1
80B_00032		Staphylococcus phage 80B	WJJ58004.1
lysin N-acetylmuramoyl-L-alanine amidase		Staphylococcus phage 8490	WVQ01261.1
Alsa1_CDS0005		Staphylococcus phage Alsa_1	WNM50355.1
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