Glycoside Hydrolase Family 73

Known Activitiespeptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-)
Mechanism Not known
3D Structure Statuslysozyme-type
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
NoteThe 3-D structure of Sphingomonas sp. strain A1 FlgJ protein of this family has recently been solved (Hashimotoa et al., BBRC 2009, in press); there is only one, unconfirmed, report of b-1,4-N-acetylmuramoylhydrolase (EC 3.2.1.17) activity
External resourcesInterPro; PFAM;
Statistics GenBank accession (2115); Uniprot accession (1213); PDB accession (3); 3D entries (3); cryst (1)
All (1884) Archaea (1) Bacteria (1829) Viruses (53) unclassified (1) Structure (3 - 1 cryst) Characterized (19)
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 endo-β-N-acetylglucosamidase (CwlG) 3.2.1.- Bacillus subtilis AC327 BAA08089.1 P39848  
 peptidoglycan hydrolase (LytG;YubE;BSU31120) 3.2.1.- Bacillus subtilis subsp. subtilis str. 168 CAB15090.1
NP_390990.1
O32083.1  
 endo-β-N-acetylglucosamidase (LytD;CwlG;BSU35780) 3.2.1.- Bacillus subtilis subsp. subtilis str. 168 AAA67857.1
CAB15595.1
NP_391459.1
P39848  
 peptidoglycan hydrolase with β-N-acetylglucosaminidase specificity (AcD;CD1304) 3.2.1.- Clostridium difficile 630 AAV54288.1
CAJ68161.1
Q5S4P9  
 peptidoglycan hydrolase with β-N-acetylglucosaminidase specificity (Acp;CPE1231) 3.2.1.- Clostridium perfringens str. 13 ADA00360.1
BAB80937.1
NP_562147.1
D2KAF8
Q8XL11
 
 N-acetylglucosaminidase (AtlA;EF0799) 3.2.1.- Enterococcus faecalis V583 AAO80613.1
AAR60023.1
NP_814543.1
   
 N-acetylglucosaminidase / β-1,4-N-acetylmuramoylhydrolase (Mur2;Mur-2) 3.2.1.17
3.2.1.96
Enterococcus hirae ATCC 9790 AAA24776.1 P39046  
 N-acetylglucosaminidase / autolysin (Acm2;lp_2645) 3.2.1.- Lactobacillus plantarum WCFS1 CAD64901.1
CCC79778.1
NP_786050.1
   
 N-acetylglucosaminidase / peptidoglycan hydrolase (AcmA;llmg_0280) 3.2.1.96 Lactococcus lactis subsp. cremoris MG1363 AAB93629.1
AAC33367.1
CAA03037.1
CAL96887.1
A2RHZ5
Q48603
 
 peptidoglycan hydrolase (AcmB; llmg_2165) 3.2.1.- Lactococcus lactis subsp. cremoris MG1363 CAC93669.1 A2RN45
Q8KKF9
 
 peptidoglycan β-N-acetylglucosaminidase (AcmA;L68758) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK04370.1
NP_266428.1
Q9CIT4  
 peptidoglycan β-N-acetylglucosaminidase (AcmB;L159324;LL1907) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK06005.1
NP_268064.1
Q9CED5  
 peptidoglycan β-N-acetylglucosaminidase (AcmC;L2183;LL1365) 3.2.1.- Lactococcus lactis subsp. lactis Il1403 AAK05463.1
NP_267521.1
Q9CFV0  
 peptidoglycan hydrolase / N-acetylglucosaminidase (Auto;Lmo1076) 3.2.1.96 Listeria monocytogenes EGD-e CAC99154.1
NP_464601.1
Q8Y842 3FI7[A]
 peptidoglycan hydrolase (FlgJ;SPH1045) 3.2.1.- Sphingomonas sp. A1 BAH11452.1 B7XH69 2ZYC[A]
3K3T[A]
 bifunctional amidase / endo-N-acetylglucosaminidase 3.2.1.- Staphylococcus aureus RN450 AAA99982.1
BAA04185.1
P52081  
 bifunctional autolysin = N-acetyl-glucosaminidase / N-acetylmuramyl-L-alanine amidase (AtlL) 3.2.1.- Staphylococcus lugdunensis ATCC 43809 ACD37724.1 B5L7M5  
 autolysin (AtlWM) 3.5.1.28 Staphylococcus warneri M BAD83399.1 Q5NTY7  
 endo-N-acetylglucosaminidase (LytB) 3.2.1.- Streptococcus pneumoniae R6 AAK99671.1
AAW08925.1
CAA09078.1
CAA09078.2
NP_358461.1
P59206.1  

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2012-01-31 © Copyright 1998-2012
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