Activities in Family	[retaining] α-1,2-branched dextransucrase (EC 2.4.1.-); [retaining] α-4,3-glucanotransferase (EC 2.4.1.-); [retaining] α-4,6-glucanotransferase (EC 2.4.1.-); [retaining] reuteransucrase (EC 2.4.1.-); [retaining] alternansucrase (EC 2.4.1.140); [retaining] dextransucrase (EC 2.4.1.5);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) 8 (inferred)
Catalytic Nucleophile/Base	Asp (inferred)
Catalytic Proton Donor	Glu (inferred)
External resources	CAZypedia;
Statistics	GenBank accession (1094); Uniprot accession (64); PDB accession (40); 3D entries (13); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
α-4,6-glucanotransferase (GARCT_00912;GtfC)	2.4.1.-	Geobacillus sp. 12AMOR1	AKM18207.1		7ZC0[A]
dextransucrase / α-1,6-glucosyltransferase (DSR-M;ASR;BN964_01347)	2.4.1.5	Leuconostoc citreum NRRL B-1299	CDX66895.1	A0A2H4A2M1 A0A2H4A2Q1	5LFC[A,B] 3.20 5NGY[A,B] α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 3.70 5O8L[A] α-D-Glcp-(1-2)-β-D-Fruf 3.60 6HTV[A] α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 3.90
bifunctional α-1,6-glucansucrase / α-1,2-branching dextransucrase (DsrE;DSR-E;BN964_01272)	2.4.1.-	Leuconostoc citreum NRRL B-1299	CDX66820.1 ACK10799.1 ACK10800.1 ACK38202.1 CAD22883.1	G8XR50 Q8G9Q2	3TTO[A,B,C,D] 3.30 3TTQ[A] 1.90 4TTU[A] α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp 2.18 4TVC[A] α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 1.85 4TVD[A] α-D-Glcp β-D-Glcp 2.30
alternansucrase / alternating α-1,3/1,6-glucosyltransferase (Asr)	2.4.1.140 2.4.1.140	Leuconostoc mesenteroides NRRL B-1355	CAB65910.2 AAQ37416.1 AAY05982.1 ACH16355.1 ACR90451.1 ACR90455.1 ACR90456.1 ACR90457.1 ACR90458.1 CAC09989.1 CAV28855.1	Q9RE05	6HVG[A,B] 2.80 6SYQ[A,B] α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 3.00 6SZI[A,B] α-D-Glcp-(1-6)-α-D-Glcp 3.00 6T16[A,B] α-D-Glcp-(1-6)-α-D-Glcp-(1-4)-α-D-Glcp 3.10 6T18[A,B] α-D-Glcp-(1-3)-α-D-Glcp-(1-6)-α-D-Glcp α-D-Glcp-(1-3)-α-D-Glcp-(1-6)-α-D-Glcp-(1-3)-α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp-(1-3)-α-D-Glcp-(1-6)-α-D-Glcp-(1-3)-α-D-Glcp-(1-6)-α-D-Glcp 3.15 6T1P[A,B] α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 3.50
ORF		Limosilactobacillus fermentum NCC3064	ASA47862.1		7DT1[A,B] 2.43
α-4,6-glucanotransferase (Lr121 GtfB)	2.4.1.-	Limosilactobacillus reuteri 121	AAU08014.2 AAU08014.1	Q5SBM0	5JBD[A,B] 1.80 5JBE[A,B] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-6)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp β-D-Glcp 2.10 5JBF[A,B] α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.19
reuteransucrase / α-1,4/1,6-glucansucrase (GtfA;GTF-A)	2.4.1.- 2.4.1.-	Limosilactobacillus reuteri 121	AAU08015.1 AAY05976.1 AAY05983.1 CAD19329.1 CAK96161.1	Q5SBL9	4AMC[A] 3.60
glucansucrase / α-1,3/1,6-glucosyltransferase (GTF180;GTF-180)	2.4.1.5	Limosilactobacillus reuteri 180	AAU08001.1	Q5SBN3	3HZ3[A] α-D-Glcp-(1-2)-β-D-Fruf 2.22 3KLK[A] 1.65 3KLL[A] α-D-Glcp-(1-4)-α-D-Glcp 2.00 4AYG[A,B] 2.00
FOL80_07450		Limosilactobacillus reuteri N4	NMV63809.1		8HU4[A,B] 2.76 8HW3[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.66 8HWK[A,B] α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.90
α-4,6-glucanotransferase (Lr2613 GtfB)	2.4.1.-	Limosilactobacillus reuteri NCC2613	ASA47879.1	A0A1Z2RUH3	7P38[A,B] 2.70 7P39[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.90
glucansucrase / α-1,3/1,6-glucosyltransferase SI (Gtf-SI;GtfC)	2.4.1.5	Streptococcus mutans	BAA26114.1 AAA88589.1 AAA88592.1 BAA26102.1 BAA26106.1 BAA26110.1 BAA26120.1	P13470	3AIB[A,B,C,D,E,F,G,H] α-D-Glcp-(1-4)-α-D-Glcp 3.09 3AIC[A,B,C,D,E,F,G,H] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 3.11 3AIE[A,B,C,D,E,F,G,H] 2.10
dextransucrase / α-1,3-glucosyltransferase (GtfB;GTF-S;GTFI)	2.4.1.5	Streptococcus mutans GS 5	AAA88588.1 BAA26101.1 BAA26105.1 BAA26109.1 BAA26113.1 BAA26119.1	P08987	8FG8[A,B] D-1,2,3,4-deoxy-Ribp 2.35 8FJ9[A,B] 2.50 8FJC[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.50 8FK4[A,B,C,D,E,F,G,H] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 3.25 8FKL[A] 1.48 8UF5[A,B] 2.50
dextransucrase D / α-1,6-glucosyltransferase (GtfD;GTF-S)	2.4.1.5	Streptococcus mutans GS 5	AAA26895.1 AAY05980.1 BAA26103.1 BAA26107.1 BAA26111.1 BAA26115.1 BAA26121.1	P49331	8FN5[A,B] 1.92
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