Glycoside Hydrolase Family 67

Known Activities	α-glucuronidase (EC 3.2.1.139); xylan α-1,2-glucuronidase (EC 3.2.1.131)
Mechanism	Inverting
3D Structure Status	( β / α ) ₈
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Glu
External resources	CAZypedia; InterPro; MEGAZYME; PFAM;
Commercial Enzyme Provider(s)	NZYTech; PROZOMIX;
Statistics	GenBank accession (167); Uniprot accession (106); PDB accession (12); 3D entries (3); cryst (0)

Summary

All (151) Archaea (2) Bacteria (132) Eukaryota (16) unclassified (1) Structure (3 ) Characterized (19)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
α-glucuronidase (Xyg)	3.2.1.139	Aeromonas caviae ME-1	BAA74508.1	Q9Z486
α-glucuronidase (CJA_2887) (Gla67A)	3.2.1.139	Cellvibrio japonicus Ueda107	AAL57752.1 ACE83468.1	B3PC73 Q8VP74	1GQI[A,B] 1GQJ[A,B] 1GQK[A,B] 1GQL[A,B] 1H41[A,B]
α-glucuronidase (GlcA67A)	3.2.1.139	Cellvibrio mixtus	AAL57753.1	Q8VP73
α-glucuronidase (LÎ±Gl;Dtur_1714)	3.2.1.139	Dictyoglomus turgidum DSM 6724	ACK42986.1	B8E3B2
α-glucuronidase (AguA)	3.2.1.139	Geobacillus stearothermophilus 236	AAG09715.1	Q9F920
α-glucuronidase (AguA)	3.2.1.139	Geobacillus stearothermophilus T-1	AAL32057.1	Q8VVD2	1K9D[A] 1L8N[A] 1MQQ[A]
α-glucuronidase (AguA)	3.2.1.139	Geobacillus stearothermophilus T-6 NCIMB 40222	AAC98128.2 ABI49940.1	Q09LY5 Q9ZFM3	1K9E[A] 1K9F[A] 1MQP[A] 1MQR[A]
α-glucuronidase (AguA;Pjdr2_1323)	3.2.1.139	Paenibacillus sp. JDR-2	ABV90485.1 ACS99998.1	A9QDR9
α-glucuronidase (XynF;Orf0393;00393-GPBOY) (Agu67A)	3.2.1.139	Prevotella bryantii B14	ADI70674.1 CAD21014.1	Q8GBY2
xylan α-1,2-glucuronidase 67A (Agu67A)	3.2.1.131	Ruminococcus albus 8	AEE64776.1 ZP_08159559.1
α-glucuronidase (AguA;TM0055)	3.2.1.139	Thermotoga maritima MSB8	AAD35149.1 CAA70702.1 NP_227871.1	P96105
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
xylan α-1,2-glucuronidase (AN9286.2)	3.2.1.131 3.2.1.139	Aspergillus nidulans FGSC A4	EAA66353.1
xylan α-1,2-glucuronidase (AguA)	3.2.1.131	Aspergillus niger CBS 120.49 / N400	CAC38119.1	Q96WX9
An14g05800 (AguA)	3.2.1.131	Aspergillus niger CBS 513.88	CAK42141.1	A2R3X3
α-glucuronidase A (AguA)	3.2.1.139	Aspergillus tubingensis NW756	CAA75605.1 CAB42223.1	O42814.1
α-glucuronidase (AguA)	3.2.1.139	Aureobasidium pullulans NRRL Y-2311-1	AAR87862.1	Q6RKQ2
α-glucuronidase (α-Glr;Glr1)	3.2.1.139	Hypocrea jecorina RUTC-30	CAA92949.1	Q99024
α-glucuronidase	3.2.1.139	Penicillium aurantiogriseum	CAZ66755.1
xylan α-1,2-glucuronidase (AGlu;AguA)	3.2.1.131	Talaromyces emersonii CBS 814.70	AAL33576.3	Q8X211

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.