| Known Activities | endoglucanase (EC 3.2.1.4) |
|---|---|
| Mechanism | Not known |
| Catalytic Nucleophile/Base | Not known |
| Catalytic Proton Donor | Not known |
| Note | The enzymes in this family were originally classified as a glycoside hydrolase family based on measurement of very weak endo-1,4-b-D-glucanase activity in one family member. The structure and mode of action of these enzymes are certainly non-canonical and they cannot be considered as bona fide glycosidases. However, they are kept in the CAZy classification on the basis of their capacity to enhance the breakdown of lignocellulose when used in conjunction with a cellulase or a mixture of cellulases. |
| External resources | InterPro; PFAM; |
| Statistics | GenBank accession (274); Uniprot accession (94); PDB accession (5); 3D entries (3); cryst (0) |
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| cellulase-enhancing factor (EG7;HjGH61B) (Cel61B=GH61B) | Hypocrea jecorina QM6A | AAP57753.1 ABH82048.1 ACK19226.1 ACR92640.1 |
Q7Z9M7 | 2VTC[A,B] | ||
| cellulase-enhancing factor (TaGH61A) (GH61A ) | Thermoascus aurantiacus | ABW56451.1 ACS05720.1 |
2YET[A,B] 3ZUD[A] |
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| cellulase-enhancing factor (131562;TtGH61E) (GH61E) | Thielavia terrestris NRRL 8126 | ACE10234.1 | 3EII[A,B,C,D] 3EJA[A,B,C,D] |
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