| Known Activities | endoglucanase (EC 3.2.1.4) |
|---|---|
| Mechanism | Not known |
| Catalytic Nucleophile/Base | Not known |
| Catalytic Proton Donor | Not known |
| Note | The enzymes in this family were originally classified as a glycoside hydrolase family based on measurement of very weak endo-1,4-b-D-glucanase activity in one family member. The structure and mode of action of these enzymes are certainly non-canonical and they cannot be considered as bona fide glycosidases. However, they are kept in the CAZy classification on the basis of their capacity to enhance the breakdown of lignocellulose when used in conjunction with a cellulase or a mixture of cellulases. |
| External resources | InterPro; PFAM; |
| Statistics | GenBank accession (274); Uniprot accession (94); PDB accession (5); 3D entries (3); cryst (0) |
| Eukaryota | ||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | |
| endo-β-1,4-glucanase (AN1602.2) | 3.2.1.4 | Aspergillus nidulans FGSC A4 | ABF50850.1 EAA64722.1 |
|||
| endo-β-1,4-glucanase IV (EGIV;Egl4;EG4) (Cel61A) | 3.2.1.4 | Hypocrea jecorina RUTC-30 | CAA71999.1 | O14405.1 | ||
| β-1,3-1,4-glucanase (peptide fragment) | 3.2.1.73 | Paecilomyces sp. J18 / Paecilomyces thermophila J18 | ||||
| metal-dependent cellulose oxidase (Gh61D) | 1.-.-.- | Phanerochaete chrysosporium K-3 | BAL43430.1 | |||
Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.