Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-); lichenase / endo-β-1,3-1,4-glucanase (EC; β-glycosidase (EC 3.2.1.-); endo-β-1,3-glucanase / laminarinase (EC; β-N-acetylhexosaminidase (EC; chitosanase (EC; β-D-galactofuranosidase (EC; β-galactosylceramidase (EC; ; β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (17166); Uniprot accession (1921); PDB accession (231); 3D entries (82); cryst (0)
All (15713) Archaea (99) Bacteria (12923) Eukaryota (2539) Viruses (11) unclassified (141) Structure (82) Characterized (562)
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 Hena1_01600   Erwinia phage Hena1 QGZ16310.1     1
 PAVTOK_15   Erwinia phage Pavtok AXF51443.1     1
 PEp14_00015 (CeL)   Erwinia phage PEp14 AEY69604.1     1
 pEpSNUABM01_075   Erwinia phage pEp_SNUABM_01 QEQ94901.1     1
 ORF   Erwinia phage phiEaP-8 AWN06195.1     1
 glycoside hydrolase   Erwinia phage vB_EamP-S6 AEJ81614.1     1
 SopranoGao_18   Klebsiella phage SopranoGao ASV45041.1     1
 POR1_70   Pseudomonas phage POR1 ALH46275.1    
 SKUL_18   Pseudomonas phage Skulduggery ARV77117.1     1
 CPT_Parlo_069   Serratia phage Parlo QBQ72218.1     1
 3S11_21   uncultured phage ASN68643.1    

Last update: 2020-02-11 © Copyright 1998-2020
AFMB - CNRS - Université d'Aix-Marseille