Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (11393); Uniprot accession (1922); PDB accession (208); 3D entries (73); cryst (0)
All (10017) Archaea (67) Bacteria (7846) Eukaryota (1982) Viruses (5) unclassified (117) Structure (73) Characterized (547)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 20 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM62 ALT83495.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM77 ALT83496.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM81 ALT83497.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM87 ALT83498.1     9
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G1 ABG88177.1 A1XWZ1  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G11 ABG88183.1 A1XWZ7  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G14 ABG88184.1 A1XWZ8  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G2 ABG88178.1 A1XWZ2  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G3 ABG88180.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G7 ABG88179.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G8 ABG88181.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G9 ABG88182.1 A1XWZ6  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41620(=PB-9) BAB12190.2
BAB12190.1
Q9HGX7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41621(=PB-18) BAB12191.2
BAB12191.1
Q9HDI4
Q9HGX7
 
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41624(=BT-4) BAB12193.1
BAB12218.1
Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41626(=BT-9) BAB12194.2
BAB12194.1
BAF62833.1
Q7LW82
Q9HDD7
 
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41632 BAB12195.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46215 BAB12196.1 Q9HGX6  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46465(=PB-267) BAB12192.1 Q9HDI4  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46467 BAB12199.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46468(P-25) BAB12198.1 Q9HGX5  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46930 BAB12197.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47183(=PRT1-TATU 1) BAB12201.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47185(=PRT2 Y) BAB12202.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47217 (=D4S1=TATU 4) BAB12204.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47217 (=D4S9) BAB12203.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47247 (=D4LIV1) BAB12205.1 Q9HDD7  
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC19346 ARD71082.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC20960 ANJ43692.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC27484 ARD71084.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC28455 ARD71086.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC30735 ARD71088.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC47835 AMY15323.1     9
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis P165 ABG88175.1 A1XWY9  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis P166 ABG88176.1 A1XWY9  
 Gp43 (fragment)   Paracoccidioides brasiliensis P196 AAT46284.1 Q6GWY1  
 Gp43 (fragment)   Paracoccidioides brasiliensis PB2 AAT46287.1 Q6GWY0  
 Gp43 (fragment)   Paracoccidioides brasiliensis PB4 AAT46288.1 Q6GWX9   4
 Gp43 (fragment)   Paracoccidioides brasiliensis PB8 AAT46289.1 Q6GWX8  
 Gp43 (fragment)   Paracoccidioides brasiliensis U1 AAT46285.1 Q6GWY2  
 GP43 (fragment)   Paracoccidioides brasiliensis V1 ABC94820.1
ABC94821.1
ABC94822.1
ABC94823.1
ABC94824.1
ABC94825.1
ABC94826.1
ABC94827.1
Q30MR5  
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii 1578 AEZ55125.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii 8334 AEZ55124.1    
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii 9840 AGT40153.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii ED01 AEZ55116.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii EE AEZ55127.1    
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM104 ALT83499.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM134 ALT83502.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM162 ALT83504.1     9
 ORF (fragment)   Paracoccidioides lutzii IEC-1744; EPM213 AFV08798.1     9
 ORF (fragment)   Paracoccidioides lutzii IEC-2005; EPM212 AFV08797.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii JHS AEZ55119.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii JMS AEZ55121.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii MFC AEZ55118.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii PLRO1 AEZ55123.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii ROSC AEZ55122.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides sp. 5979 AEZ55120.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides sp. MS1 AEZ55117.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides sp. MS2 AEZ55126.1    
 ORF (fragment)   Paracoccidioides sp. SUM BAN81904.1     9
 SNOG_14280   Parastagonospora nodorum SN15 EAT78517.2     31
 ORF   Passalora fulva 0WU AQA29342.1     9
 endo-β-1,4-glucanase (EGb1;EGb2) (Cel5C) 3.2.1.4 Penicillium brasilianum IBT 20888 ACB06750.1 B8Q961   5
 endo-β-1,4-glucanase (Egl1)   Penicillium crustosum 601 AHA15977.1     5
 endoglucanase 5C (PdCel5C) (Cel5C) 3.2.1.4 Penicillium decumbens 114-2 AFG25592.1     4
 endoglucanase II / 5A (Eg2;Egl2) (Cel5A) 3.2.1.4 Penicillium decumbens 114-2 / JU-A10 ABY28340.1 A9Z054   5
 endoglucanase/cellulase 1   Penicillium digitatum Pd01 AFV30215.1     5
 endoglucanase 1 (Egl1;Pe-Egl1) (partial) 3.2.1.4 Penicillium echinulatum 9A01S2 ACR82487.1 C5J4L7   5
 endo-β-1,4-glucanase II (Egl2) 3.2.1.4 Penicillium janthinellum Biourge IMET 43733 (C41) CAA61740.1 Q12665   5
 β-primeverosidase (Bgl2) 3.2.1.149 Penicillium multicolor TS-5 / IAM7153 BAG70961.1 B5MEI8   23
 endo-β-mannanase (Ma;PoMan5A) (Man5A) 3.2.1.78 Penicillium oxalicum GZ-2 AGW24296.1     7
 endo-β-1,4-glucanase 4   Penicillium oxalicum GZ-2 AIO06743.1     4
 endo-β-1,4-glucanase 5   Penicillium oxalicum GZ-2 AIO06744.1     5
 Pc12g06760   Penicillium rubens Wisconsin 54-1255 CAP80303.1 B6H0N6   22
 Pc12g07900   Penicillium rubens Wisconsin 54-1255 CAP80417.1 B6GXM2   7
 Pc13g14840   Penicillium rubens Wisconsin 54-1255 CAP92553.1 B6H2P2   23
 Pc16g10690   Penicillium rubens Wisconsin 54-1255 CAP93739.1 B6H988   12
 Pc18g02600   Penicillium rubens Wisconsin 54-1255 CAP94484.1 B6HCY2   9
 Pc18g06080   Penicillium rubens Wisconsin 54-1255 CAP94832.1 B6HCI5   5
 Pc20g01940   Penicillium rubens Wisconsin 54-1255 CAP85523.1 B6HE68   5
 Pc20g03840   Penicillium rubens Wisconsin 54-1255 CAP85713.1 B6HH54   12
 Pc21g05470   Penicillium rubens Wisconsin 54-1255 CAP95444.1 B6HHJ3   7
 Pc21g14050   Penicillium rubens Wisconsin 54-1255 CAP96302.1 B6HNS9   7
 Pc21g14410   Penicillium rubens Wisconsin 54-1255 CAP96338.1 B6HI44   4
 Pc12g07940   Penicillium rubens Wisconsin 54-1255 CAP80421.1 B6GXM5   9
 Pc22g19230   Penicillium rubens Wisconsin 54-1255 CAP99211.1 B6HVQ6   5
 glycoside hydrolase family 5 endoglucanase, partial (Glu-1) (fragment)   Penicillium sp. 0728-003 B PDA/MF07-022 CDL74340.1     5
 glycoside hydrolase family 5 endoglucanase, partial (Glu-2) (fragment)   Penicillium sp. 0728-003 B PDA/MF07-022 CDL74341.1     5
 β-mannanase (Man5C6;Man5) 3.2.1.78 Penicillium sp. enrichment culture clone C6 / ACCC32495 AEV41143.1     7
 endo-β-1,4-mannanase (Man5F63) 3.2.1.78 Penicillium sp. F63 XC-2012 / CGMCC 1669 AFC38441.1     7
 endoglucanase (Cel5A) 3.2.1.4 Pestalotiopsis sp. AN 7 BAI66446.1 D2KTU9   5
 family 5 glycoside hydrolase (fragment)   Phakopsora pachyrhizi ALL40758.1    
 ORF (fragment)   Phakopsora pachyrhizi ALL40826.1    
 ORF   Phakopsora pachyrhizi ALL40863.1     7
 family 5 glycoside hydrolase (fragment)   Phakopsora pachyrhizi ALL41339.1    
 endoglucanase (Cel5A) (Cel5A)   Phanerochaete chrysosporium AAU12275.2
AAU12275.1
Q66NB7   5
 β-xylosidase (Xyl5;PcXyl5;PcGH5) (partial) 3.2.1.37 Phanerochaete chrysosporium AHL69750.2
AIA81045.1
    22
 β-mannanase 5D (Man5D) 3.2.1.78 Phanerochaete chrysosporium RP78 ABG79370.1 Q0PQY8   7
 β-mannanase 5C (Man5C)   Phanerochaete chrysosporium RP78 ABG79371.1 Q0PQY7   7
 endo-β-1,4-mannanase   Phaseolus vulgaris AHA84179.1     7
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