Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (12399); Uniprot accession (1922); PDB accession (212); 3D entries (75); cryst (0)
All (11020) Archaea (67) Bacteria (8762) Eukaryota (2065) Viruses (6) unclassified (120) Structure (75) Characterized (547)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 21 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 Os08g0484100   Oryza sativa Japonica Group BAD10703.1
BAD09304.1
BAF23993.1
Q6YTT8   14
 Os02g0596200   Oryza sativa Japonica Group BAD16839.1
BAD21617.1
BAF09234.1
BAS79555.1
CAW49143.1
CAW50881.1
CBC20360.1
Q6ZI46   11
 Os02g0766900   Oryza sativa Japonica Group BAD17320.1
BAD17132.1
BAF10140.1
BAS81070.1
A3ABP6
Q6Z310
  7
 Os06g0311600   Oryza sativa Japonica Group BAD61770.1
BAF19398.1
BAS97441.1
Q0DCM5   7
 OSJNBb0006B22.2 or OSJNBb0059K16.9   Oryza sativa Japonica Group AAV44080.1
AAV44120.1
BAS93345.1
Q5W6G0   7
 Os05g0244500   Oryza sativa Japonica Group AAV43969.1
BAF16925.1
BAS92988.1
Q5W708   14
 Os11g0118200 (fragment)   Oryza sativa Japonica Group BAF27440.1
BAG97285.1
BAT12428.1
B7EY38
Q2RBB1
  7
 endo-β-1,4-mannanase 8 (OsMan8;Os12g0117300;LOC_Os12g02520)   Oryza sativa Japonica Group ABA95648.1
BAF29018.1
BAT15617.1
A3CED8
Q0IQJ7
Q2QYI9
  7
 Os01g0746700   Oryza sativa Japonica Group BAB56016.1
BAC05600.1
BAF06144.1
BAS74321.1
Q0JJD4   7
 OSTLU_4036 (fragment)   Ostreococcus lucimarinus CCE9901 ABO94548.1 A4RSG2   7
 OSTLU_3863 (fragment)   Ostreococcus lucimarinus CCE9901 ABO95765.1 A4RVU7   7
 OSTLU_26901   Ostreococcus lucimarinus CCE9901 ABO99132.1 A4S5W1   32
 OSTLU_92070   Ostreococcus lucimarinus CCE9901 ABO94043.1 A4RQL3   32
 OSTLU_42201 (fragment)   Ostreococcus lucimarinus CCE9901 ABP00730.1 A4SAC9   7
 Ot01g00930   Ostreococcus tauri OTTH0595 CAL50004.1 Q01GZ0   32
 Ot20g00120   Ostreococcus tauri OTTH0595 CAL56661.1 Q00S04   7
 Ot04g01830   Ostreococcus tauri OTTH0595 CAL51581.1 Q01B66   7
 Ot12g02510   Ostreococcus tauri OTTH0595 CAL57343.1 Q00XQ8   32
 Ot02g07200   Ostreococcus tauri OTTH0595 CAL52595.1 Q01DK8   7
 immunodominant antigen gp43, partial (fragment)   Paracoccidioides brasiliensis ASO96830.1     9
 immunodominant antigen gp43, partial (fragment)   Paracoccidioides brasiliensis ASO96831.1     9
 Gp43 (fragment)   Paracoccidioides brasiliensis AEJ22066.1     9
 immunodominant antigen Gp43 (fragment)   Paracoccidioides brasiliensis ACF72730.1
ACF72731.1
ACF72732.1
ACF72733.1
ACF72734.1
ACF72735.1
ACF72736.1
ACF72737.1
ACF72738.1
ACF72739.1
ACF72740.1
ACF72741.1
ACF72742.1
ACF72743.1
B5AQR3  
 immunodominant antigen Gp43 (fragment)   Paracoccidioides brasiliensis ACF72744.1
ACF72745.1
B5AQS7   9
 Gp43 (fragment)   Paracoccidioides brasiliensis (VARIOUS STRAINS) AAY58372.1
AAY58373.1
AAY58374.1
AAY58375.1
AAY58376.1
AAY58377.1
AAY58378.1
AAY58379.1
AAY58380.1
AAY58381.1
AAY58382.1
AAY58383.1
AAY58384.1
AAY58385.1
AAY58386.1
AAY58387.1
AAY58388.1
AAY58389.1
AAY58390.1
AAY58391.1
AAY58392.1
AAY58393.1
AAY58394.1
AAY58395.1
AAY58396.1
AAY58397.1
AAY58398.1
AAY58399.1
AAY58400.1
AAY58401.1
AAY58402.1
AAY58403.1
AAY58404.1
AAY58405.1
AAY58406.1
AAY58407.1
AAY58408.1
AAY58409.1
AAY58410.1
AAY58411.1
AAY58412.1
AAY58413.1
AAY58414.1
AAY58415.1
AAY58416.1
AAY58417.1
AAY58418.1
AAY58419.1
AAY58420.1
AAY58421.1
AAY58422.1
AAY58423.1
AAY58424.1
AAY58425.1
AAY58426.1
AAY58427.1
AAY58428.1
AAY58429.1
AAY58430.1
AAY58431.1
AAY58432.1
AAY58433.1
AAY58434.1
AAY58435.1
AAY58436.1
Q30MW3  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis (VARIOUS STRAINS) BAB12200.2
BAB12200.1
BAF62830.1
BAF62831.1
BAF62832.1
BAF62834.1
BAF62836.1
BAF62837.1
BAF62838.1
BAF62839.1
BAF62840.1
BAF62841.1
BAF62842.1
BAF62843.1
BAF62844.1
BAF62845.1
BAF62846.1
BAF62847.1
BAF62848.1
BAF62849.1
BAF62850.1
BAF62851.1
BAF62852.1
Q7LW78
Q9HDD7
 
 immunodominant antigen, partial (Gp43) (fragment)   Paracoccidioides brasiliensis 29521 AUW36786.1     9
 immunodominant antigen, partial (Gp43) (fragment)   Paracoccidioides brasiliensis 37550 AUW36787.1     9
 immunodominant antigen, partial (Gp43) (fragment)   Paracoccidioides brasiliensis 43619 AUW36788.1     9
 immunodominant antigen, partial (Gp43) (fragment)   Paracoccidioides brasiliensis 43659 AUW36789.1     9
 immunodominant antigen, partial (Gp43) (fragment)   Paracoccidioides brasiliensis 46677 AUW36790.1     9
 Gp43 (fragment)   Paracoccidioides brasiliensis ATCC 60855 AAT46286.1 Q6GWY1  
 GP43 (fragment)   Paracoccidioides brasiliensis B12 ABC94844.1
ABC94845.1
ABC94846.1
ABC94847.1
ABC94848.1
ABC94849.1
ABC94850.1
ABC94851.1
Q30MW3  
 GP43 (fragment)   Paracoccidioides brasiliensis B17 ABC94852.1
ABC94853.1
ABC94854.1
ABC94855.1
ABC94856.1
ABC94857.1
ABC94858.1
ABC94859.1
Q30MW3  
 GP43 (fragment)   Paracoccidioides brasiliensis B18 ABC94828.1
ABC94829.1
ABC94830.1
ABC94831.1
ABC94832.1
ABC94833.1
ABC94834.1
ABC94835.1
Q30MU7  
 gp43   Paracoccidioides brasiliensis B339 AAC49253.1
AAC49253.2
AAG36698.1
BAF62835.1
Q01575   9
 GP43 (fragment)   Paracoccidioides brasiliensis B7 ABC94836.1
ABC94837.1
ABC94838.1
ABC94839.1
ABC94840.1
ABC94841.1
ABC94842.1
ABC94843.1
Q30MU2  
 43 kDa secreted glycoprotein (fragment)   Paracoccidioides brasiliensis CABBASOUS AAT39126.1 Q6IVV1  
 43 kDa secreted glycoprotein (fragment)   Paracoccidioides brasiliensis DASYPUS AAT39127.1 Q6IVV1  
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM106 ALT83500.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM127 ALT83501.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM155 ALT83503.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM29 ALT83491.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM35 ALT83492.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM54 ALT83493.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM60 ALT83494.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM62 ALT83495.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM77 ALT83496.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM81 ALT83497.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis EPM87 ALT83498.1     9
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G1 ABG88177.1 A1XWZ1  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G11 ABG88183.1 A1XWZ7  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G14 ABG88184.1 A1XWZ8  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G2 ABG88178.1 A1XWZ2  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G3 ABG88180.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G7 ABG88179.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G8 ABG88181.1 A1XWZ3  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis G9 ABG88182.1 A1XWZ6  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41620(=PB-9) BAB12190.2
BAB12190.1
Q9HGX7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41621(=PB-18) BAB12191.2
BAB12191.1
Q9HDI4
Q9HGX7
 
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41624(=BT-4) BAB12193.1
BAB12218.1
Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41626(=BT-9) BAB12194.2
BAB12194.1
BAF62833.1
Q7LW82
Q9HDD7
 
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM41632 BAB12195.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46215 BAB12196.1 Q9HGX6  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46465(=PB-267) BAB12192.1 Q9HDI4  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46467 BAB12199.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46468(P-25) BAB12198.1 Q9HGX5  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM46930 BAB12197.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47183(=PRT1-TATU 1) BAB12201.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47185(=PRT2 Y) BAB12202.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47217 (=D4S1=TATU 4) BAB12204.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47217 (=D4S9) BAB12203.1 Q9HDD7  
 43 kDa glycoprotein (Gp43) (fragment)   Paracoccidioides brasiliensis IFM47247 (=D4LIV1) BAB12205.1 Q9HDD7  
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC19346 ARD71082.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC20960 ANJ43692.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC27484 ARD71084.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC28455 ARD71086.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC30735 ARD71088.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides brasiliensis IPEC47835 AMY15323.1     9
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis P165 ABG88175.1 A1XWY9  
 43 kDa glycoprotein immunodominant antigen (GP43) (fragment)   Paracoccidioides brasiliensis P166 ABG88176.1 A1XWY9  
 Gp43 (fragment)   Paracoccidioides brasiliensis P196 AAT46284.1 Q6GWY1  
 Gp43 (fragment)   Paracoccidioides brasiliensis PB2 AAT46287.1 Q6GWY0  
 Gp43 (fragment)   Paracoccidioides brasiliensis PB4 AAT46288.1 Q6GWX9   4
 Gp43 (fragment)   Paracoccidioides brasiliensis PB8 AAT46289.1 Q6GWX8  
 Gp43 (fragment)   Paracoccidioides brasiliensis U1 AAT46285.1 Q6GWY2  
 GP43 (fragment)   Paracoccidioides brasiliensis V1 ABC94820.1
ABC94821.1
ABC94822.1
ABC94823.1
ABC94824.1
ABC94825.1
ABC94826.1
ABC94827.1
Q30MR5  
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii 1578 AEZ55125.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii 8334 AEZ55124.1    
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii 9840 AGT40153.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii ED01 AEZ55116.1    
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii EE AEZ55127.1    
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM104 ALT83499.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM134 ALT83502.1     9
 immunodominant antigen Gp43, partial (fragment)   Paracoccidioides lutzii EPM162 ALT83504.1     9
 ORF (fragment)   Paracoccidioides lutzii IEC-1744; EPM213 AFV08798.1     9
 ORF (fragment)   Paracoccidioides lutzii IEC-2005; EPM212 AFV08797.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii JHS AEZ55119.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii JMS AEZ55121.1     9
 immunodominant antigen Gp43, partial (Gp43) (fragment)   Paracoccidioides lutzii MFC AEZ55118.1    
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