Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (11393); Uniprot accession (1922); PDB accession (208); 3D entries (73); cryst (0)
All (10017) Archaea (67) Bacteria (7846) Eukaryota (1982) Viruses (5) unclassified (117) Structure (73) Characterized (547)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 20 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 KAFR_0K01030 (Kafr0k01030)   Kazachstania africana CBS 2517 CCF60459.1     12
 KNAG_0B03180 (Knag0b03180)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK68759.1     9
 KNAG_0E03600 (Knag0e03600)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK70617.1     12
 KNAG_0F03220 (Knag0f03220)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK70984.1     9
 KNAG_0J00880 (Knag0j00880)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72170.1     49
 KNAG_0M00890 (Knag0m00890)   Kazachstania naganishii CBS 8797 type strain:CBS 8797 CCK72942.1     9
 KLLA0F18788g   Kluyveromyces lactis NRRL Y-1140 CAG98630.1 Q6CJG7   49
 KLLA0C05324g   Kluyveromyces lactis NRRL Y-1140 CAH01288.1
CAA86949.1
Q12628   9
 KLLA0B11704g   Kluyveromyces lactis NRRL Y-1140 CAH02444.1 Q6CVI8   12
 KLMA_40105   Kluyveromyces marxianus DMKU3-1042 BAO40129.1     49
 KLMA_10234   Kluyveromyces marxianus DMKU3-1042 BAO37856.1     9
 KLMA_70317   Kluyveromyces marxianus DMKU3-1042 BAO42165.1     12
 KMAR_10210   Kluyveromyces marxianus NBRC 1777 BAP69418.1     9
 KMAR_70289   Kluyveromyces marxianus NBRC 1777 BAP73573.1     12
 KMAR_40114   Kluyveromyces marxianus NBRC 1777 BAP71622.1     49
 ORF (fragment)   Koerneria sudhausi SB413 ADY92762.1     2
 ATY40_BA7502724 (Exg1)   Komagataella pastoris ATCC 28485 ANZ75686.1     9
 ATY40_BA7504625 (Spr1)   Komagataella pastoris ATCC 28485 ANZ77526.1     9
 ATY40_BA7502971 (Yir007W)   Komagataella pastoris ATCC 28485 ANZ75469.1     12
 ATY40_BA7500992   Komagataella pastoris ATCC 28485 ANZ74575.1     49
 exo-β-1,3-glucanase (Eg;Exg1) 3.2.1.58 Komagataella pastoris X-33 AAY28969.1 Q2TCV2   9
 AT249_GQ6705072 (Spr1)   Komagataella phaffii ATCC 76273 AOA64999.1     9
 AT249_GQ6704659 (Yir007W)   Komagataella phaffii ATCC 76273 AOA65127.1     12
 AT249_GQ6700497 (Exg1)   Komagataella phaffii ATCC 76273 AOA62628.1     9
 PP7435_Chr1-0852   Komagataella phaffii CBS 7435 CCA36990.1     49
 PP7435_Chr2-0842 (fragment)   Komagataella phaffii CBS 7435 CCA38524.1     9
 PP7435_Chr4-0271 (Exg2)   Komagataella phaffii CBS 7435 CCA40446.1     9
 PP7435_Chr4-0672   Komagataella phaffii CBS 7435 CCA40830.1     12
 PAS_chr2-1_0454 (Exg;Exg1) 3.2.1.58 Komagataella phaffii GS115 CAY69081.1
AOA67579.1
C4R0Q7   9
 PAS_chr1-4_0082   Komagataella phaffii GS115 CAY67911.1
AOA65441.1
C4QXD8   49
 PAS_chr4_0692   Komagataella phaffii GS115 CAY71953.1
AOA70150.1
C4R8M8   9
 PAS_chr4_0321   Komagataella phaffii GS115 CAY71564.1
AOA70086.1
C4R7I9   12
 AT249_GQ6702105   Komagataella phaffii WT AOA60792.1     49
 ORF (fragment)   Lacazia loboi 10-RMS ABW86801.1
ABW86803.1
ABW86804.1
ABW86805.1
ABW86807.1
ABW86808.1
ABW86809.1
ABW86810.1
ABW86811.1
ABW86813.1
ABW86814.1
ABW86815.1
ABW86816.1
ABW86817.1
ABW86821.1
B5KRK0   9
 ORF (fragment)   Lacazia loboi 11-A ABW86819.1 B5KRL8   9
 ORF (fragment)   Lacazia loboi 12-S2 ABW86802.1 B5KRK1   9
 ORF (fragment)   Lacazia loboi 13-FAV ABW86820.1 B5KRL9   9
 ORF (fragment)   Lacazia loboi 14-BVS ABW86818.1 B5KRL7   9
 ORF (fragment)   Lacazia loboi 17-LFC ABW86822.1 B5KRM1   9
 gp43-like (fragment)   Lacazia loboi 2004 AAW21849.1 Q49MA8  
 ORF (fragment)   Lacazia loboi 33-RPGB ABW86806.1 B5KRK5   9
 ORF (fragment)   Lacazia loboi 4-RPM ABW86812.1 B5KRL1   9
 LACBIDRAFT_292256   Laccaria bicolor S238N-H82 EDR14294.1     30
 LACBIDRAFT_294893 (fragment)   Laccaria bicolor S238N-H82 EDR05274.1     30
 EXG1   Lachancea kluyveri CBS3082 AAO32563.1 Q875R9   9
 KLTH0F13706g   Lachancea thermotolerans CBS 6340 CAR24346.1     12
 KLTH0C07414g   Lachancea thermotolerans CBS 6340 CAR22109.1     49
 KLTH0H06974g   Lachancea thermotolerans CBS 6340 CAR30320.1     9
 endo-β-1,4-mannanase (Man1) 3.2.1.78 Lactuca sativa CAC51690.3 Q93X40   7
 ORF   Lagenidium giganteum ARSEF 373 AIK98135.1     27
 β-1,6-glucanase (Glu1)   Lecanicillium fungicola 150-1 AAO63562.1 Q7ZA48   15
 exo-β-1,3-glucanase (Exg1) 3.2.1.58 Lentinula edodes H600 BAD97445.1
BAD97446.1
Q53UH0   9
 glycoside hydrolase family 5 endoglucanase, partial (fragment)   Lentinula edodes M-LE-777 CDL74352.1    
 Man7 / LesaMAN7 (fragment)   Lepidium sativum AED01931.1     7
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX90804.1 E4ZHH1   16
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91472.1 E4ZJ41   9
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91659.1 E4ZK64   49
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX91913.1 E5R4E5   5
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX93149.1 E4ZPC4   7
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX94583.1 E4ZSZ5   4
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96078.1 E4ZWV2   7
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX96356.1 E4ZYB1   9
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97550.1 E5A2B5   9
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97708.1 E5A1Z1   16
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97977.1 E5A3V3   12
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBY01903.1 E5AFB4   7
 ORF (fragment)   Leptosphaeria maculans JN3 v23.1.3 CBX91542.1 E4ZJB1   9
 ORF (fragment)   Leptosphaeria maculans JN3 v23.1.3 CBY00459.1 E5A9W8   16
 ORF (fragment)   Leptosphaeria maculans JN3 v23.1.3 CBY00460.1 E5A9W9   16
 endocellulase (Cel5A)   Leucoagaricus gongylophorus Ae322 CDJ79817.1     5
 endocellulase (Cel5B)   Leucoagaricus gongylophorus Ae322 CDJ79818.1     5
 β-mannosidase   Lichtheimia corymbifera CGMCC 4974 AMB61311.1     7
 LRAMOSA05721   Lichtheimia ramosa CDS13545.1     7
 LRAMOSA05754   Lichtheimia ramosa CDS13578.1     12
 LRAMOSA07974   Lichtheimia ramosa CDS05446.1     12
 LRAMOSA09953   Lichtheimia ramosa CDS08592.1     27
 LRAMOSA10401   Lichtheimia ramosa CDS09041.1     50
 LRAMOSA04528   Lichtheimia ramosa CDS12333.1     7
 LRAMOSA07070   Lichtheimia ramosa CDS04115.1     9
 LRAMOSA08274   Lichtheimia ramosa CDS05746.1     9
 LRAMOSA09878   Lichtheimia ramosa CDS08517.1     7
 EgL (fragment)   Limacella glischra AEQ58911.1     5
 glycoside hydrolase family 5 endoglucanase, partial (fragment)   Limacella guttata FB-LG-51 CDL74327.1    
 EgL (fragment)   Limacella illinita AEQ58912.1     5
 GH5A   Limnoria quadripunctata ADE58567.1 D5IEF5   10
 GH5C   Limnoria quadripunctata ADE58568.1 D5IEF6   10
 GH5E   Limnoria quadripunctata ADE58569.1 D5IEF7   10
 ORF   Lolium perenne ARJ57515.1     15
 ORF   Lolium perenne ARJ57513.1     15
 ORF   Lolium perenne ARJ57514.1     15
 unknown   Lotus japonicus AFK43830.1     7
 unknown   Lotus japonicus AFK46805.1     7
 unknown (fragment)   Lotus japonicus AFK34066.1     7
 unknown   Lotus japonicus AFK35120.1     14
 unknown (fragment)   Lotus japonicus AFK38496.1     14
 unknown   Lotus japonicus AFK46453.1     11
 unknown (fragment)   Lotus japonicus AFK48266.1     11
 endo-β-1,4-glucanase 1 (Egl1) 3.2.1.4 Macrophomina phaseolina AAB51451.1 Q12638   5
 endo-β-1,4-glucanase 2 (Egl2) 3.2.1.4 Macrophomina phaseolina AAB03889.1 Q12637   5
 MG07846.4 (fragment)   Magnaporthe oryzae 70-15 XP_367942.1     22
Top


Last update: 2017-10-09 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille