Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (14118); Uniprot accession (1922); PDB accession (218); 3D entries (77); cryst (0)
All (12730) Archaea (93) Bacteria (10317) Eukaryota (2191) Viruses (8) unclassified (121) Structure (77) Characterized (551)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 22 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 CPAR2_106620   Candida parapsilosis CDC317 CCE40627.1     9
 CPAR2_700340   Candida parapsilosis CDC317 CCE45030.1     49
 CHGG_09153 (Cglo-Bgl501)   Chaetomium globosum CBS 148.51 EAQ85139.1     9
 β-mannanase (CsMan5A) (Man5A) 3.2.1.78 Chaetomium sp. CQ31 ADW82104.1     7
 mannanase (fragment)   Cherax quadricarinatus AIN40245.1     10
 ManB (fragment)   Chlorella vulgaris C-169 BAA99563.1 Q9LRG5   7
 Glycosyl hydrolase family 5, partial (fragment)   Chytridiomycota sp. NHY-2018 WSF2c AWI66944.1     5
 Glycosyl hydrolase family 5, partial (fragment)   Chytridiomycota sp. NHY-2018 WSF2c AWI66944.1     5
 cellulase (CelA;CsCelA) 3.2.1.4 Ciboria shiraiana AIC79156.1     5
 glycoside hydrolase family 5 endoglucanase, partial (fragment)   Cladosporium sp. 0629-033 2 WA Aa/MF06-304 CDL74329.1     5
 ORF (fragment)   Clonostachys rosea 0628-013 3 PDA/MF06-095 CDL74338.1     5
 Eg8-20   Clonostachys rosea f. catenulata HL-1-1 AFK10489.1     5
 ORF   Coccidioides posadasii ABA54914.1 Q3HYB8   12
 endo-β-1,4-mannanase (ManA;CaMANA) 3.2.1.78 Coffea arabica CAC08208.1
AAX01860.1
Q9FT02   7
 endo-β-1-4-mannanase (ManB;CaMANB) 3.2.1.78 Coffea arabica CAC08442.1 Q9FT03   7
 ORF (fragment)   Colletotrichum coccodes 0629-022 1 A PDA/MF06-283 CDL74331.1     5
 ORF (fragment)   Colletotrichum coccodes 0629-022 1 A PDA/MF06-283 CDL74332.1     5
 glycoside hydrolase family 5 protein   Coniochaeta hoffmannii CBS 245.38 AUS45833.1     5
 glycoside hydrolase family 5 protein   Coniochaeta hoffmannii CBS 245.38 AUS45836.1     5
 glycoside hydrolase family 5 protein   Coniochaeta hoffmannii CBS 245.38 AUS45855.1     5
 glycoside hydrolase family 5 protein (fragment)   Coniochaeta hoffmannii CBS 245.38 AUS45852.1     5
 glycoside hydrolase family 5 protein   Coniochaeta hoffmannii CBS 245.38 AUS45863.1     5
 CC1G_04257   Coprinopsis cinerea okayama7#130 EAU88551.2     30
 CC1G_02860   Coprinopsis cinerea okayama7#130 EAU93630.1     30
 ORF   Coptotermes formosanus AGM32066.1     2
 ORF (fragment)   Coptotermes formosanus AGM32347.1     2
 ORF (fragment)   Coptotermes formosanus AGM32171.1     1
 ORF (fragment)   Coptotermes formosanus AGM32296.1    
 ORF (fragment)   Coptotermes formosanus AGM32613.1     1
 ORF   Coptotermes formosanus AGM32918.1    
 ORF (fragment)   Coptotermes formosanus AGM33006.1     2
 ORF (fragment)   Coptotermes formosanus AGM33013.1     1
 ORF (partial)   Cordyceps fumosorosea Ifr AsC AIK98138.1     27
 A9K55_008696   Cordyceps militaris ATCC 34164 ATY62578.1     15
 A9K55_000635   Cordyceps militaris ATCC 34164 ATY67020.1     27
 A9K55_009287   Cordyceps militaris ATCC 34164 ATY62125.1     5
 A9K55_003598   Cordyceps militaris ATCC 34164 ATY58494.1     24
 A9K55_000717   Cordyceps militaris ATCC 34164 ATY66476.1     9
 A9K55_005048   Cordyceps militaris ATCC 34164 ATY64700.1     12
 A9K55_008189   Cordyceps militaris ATCC 34164 ATY62039.1     11
 CGB_E4160W   Cryptococcus gattii WM276 ADV22545.1     9
 CGB_A6500C   Cryptococcus gattii WM276 ADV19799.1     12
 CGB_L3610C   Cryptococcus gattii WM276 ADV25348.1     50
 CGB_B3770C   Cryptococcus gattii WM276 ADV20345.1     9
 CGB_D2240C   Cryptococcus gattii WM276 ADV21668.1     9
 CGB_F4310C   Cryptococcus gattii WM276 ADV23065.1     9
 CGB_J1490W   Cryptococcus gattii WM276 ADV24619.1     9
 CGB_L3160C   Cryptococcus gattii WM276 ADV25373.1     12
 CGB_A9170W   Cryptococcus gattii WM276 ADV19959.1    
 CGB_F3670W   Cryptococcus gattii WM276 ADV22976.1     22
 β-glucocerebrosidase (EGCrP1;CNAG_00623) 3.2.1.45 Cryptococcus neoformans var. grubii H99 BAL46040.1
AFR92751.1
AFR92751.2
    12
 CNAG_02225   Cryptococcus neoformans var. grubii H99 AFR95595.1     9
 CNAG_05652   Cryptococcus neoformans var. grubii H99 AFR99083.1     50
 CNAG_00373   Cryptococcus neoformans var. grubii H99 AFR92508.1     9
 CNAG_05138   Cryptococcus neoformans var. grubii H99 AFR94403.1
AFR94403.2
    9
 CNAG_00939 (fragment)   Cryptococcus neoformans var. grubii H99 AFR95190.1     9
 CNAG_05766   Cryptococcus neoformans var. grubii H99 AFR96086.2
AFR96086.1
    22
 CNAG_05803   Cryptococcus neoformans var. grubii H99 AFR96122.1     9
 steryl β-glucosidase (EGCrP2;CNAG_05607) (vacuolar) 3.2.1.104 Cryptococcus neoformans var. grubii H99 AFR99035.1     12
 CNAG_00799   Cryptococcus neoformans var. grubii H99 AFR92930.1    
 CKF44_000834 (fragment)   Cryptococcus neoformans var. grubii KN99 AUB24953.1     9
 CKF44_000537   Cryptococcus neoformans var. grubii KN99 AUB22216.1     12
 CKF44_005183   Cryptococcus neoformans var. grubii KN99 AUB25961.1     22
 CKF44_005217   Cryptococcus neoformans var. grubii KN99 AUB26004.1     9
 CKF44_004606   Cryptococcus neoformans var. grubii KN99 AUB24055.1     9
 CKF44_000313   Cryptococcus neoformans var. grubii KN99 AUB21944.1     9
 CKF44_005075   Cryptococcus neoformans var. grubii KN99 AUB29314.1     50
 CKF44_000704   Cryptococcus neoformans var. grubii KN99 AUB22412.1    
 CKF44_005031   Cryptococcus neoformans var. grubii KN99 AUB29264.1     12
 CKF44_002007   Cryptococcus neoformans var. grubii KN99 AUB25420.1     9
 exo-β-1,3-glucanase (fragment)   Cryptococcus neoformans var. neoformans AAM26269.1 Q8NKG2   9
 cellulase (CelC)   Cryptococcus neoformans var. neoformans 309 CAP67 CAD31110.1 Q8NIP0   9
 CNF01760   Cryptococcus neoformans var. neoformans JEC21 AAW44208.1
AAW44208.2
Q5KFH2   9
 CNF02120   Cryptococcus neoformans var. neoformans JEC21 AAW44253.1
AAW44253.2
Q5KFD5   22
 CND00790   Cryptococcus neoformans var. neoformans JEC21 AAW43031.1
AAW43031.2
Q5KJ34   9
 CNE03150   Cryptococcus neoformans var. neoformans JEC21 AAW43562.1 Q5KGL9   9
 CNA07770   Cryptococcus neoformans var. neoformans JEC21 AAW41305.1 Q5KN45  
 CNL04840   Cryptococcus neoformans var. neoformans JEC21 AAW46509.1
AAW46508.1
Q5K8Q6   9
 CNA06030   Cryptococcus neoformans var. neoformans JEC21 AAW41138.1 Q5KNL9   12
 CNH02900   Cryptococcus neoformans var. neoformans JEC21 AAW45154.1 Q5KD09   50
 CNA03300   Cryptococcus neoformans var. neoformans JEC21 AAW40834.1 Q5KPC6   9
 CNH02490   Cryptococcus neoformans var. neoformans JEC21 AAW45118.1
AAW45117.1
Q5KCW8
Q5KCW9
  12
 carboxymethylcellulase (CsCMCase) 3.2.1.4 Cryptococcus sp. S-2 ABP02069.1 A4UU22   5
 ORF   Cryptomeria japonica var. sinensis BBE74942.1     11
 endo-β-1,4-mannanase (Man;CaMan) 3.2.1.78 Cryptopygus antarcticus ABV68808.1 B4XC07 4OOU[A,B]
4OOZ[A,B]
10
 endo-β-mannanase (Man;CmMAN)   Cucumis melo subsp. melo ADN34185.1 E5GCI6   7
 endoglycoceramidase (EGCase) 3.2.1.123 Cyanea nozakii BAB16369.1
BAB16370.1
Q9GV15
Q9GV16
  27
 CYFA0S_02e07932g   Cyberlindnera fabianii YJS4271 CDR38887.1     49
 CYFA0S_03e01992g   Cyberlindnera fabianii YJS4271 CDR39305.1     12
 CYFA0S_06e03532g   Cyberlindnera fabianii YJS4271 CDR41190.1     9
 CYFA0S_09e02652g   Cyberlindnera fabianii YJS4271 CDR42395.1     9
 CYFA0S_38e00672g   Cyberlindnera fabianii YJS4271 CDR47857.1     22
 ORF (fragment)   Cylindrocarpon sp. 0629-017 3 A WA/MF06-299 CDL74333.1     5
 glycoside hydrolase family 5 endoglucanase, partial (fragment)   Cystoderma carcharias FB-CC-22 CDL74334.1    
 endo-β-mannanase (Man;DfMAN) (fragment)   Datura ferox AAO06964.1 Q8GTA2   7
 endo-β-mannanase (DcMan1) 3.2.1.78 Daucus carota AAN34823.1 Q8H6B4   7
 DEHA0F26378g   Debaryomyces hansenii CBS767 CAG89835.1 Q6BK51   49
 DEHA0D09196g   Debaryomyces hansenii CBS767 CAG86973.1 Q6BSJ3   9
 DEHA0F01716g   Debaryomyces hansenii CBS767 CAG88733.1 Q6BMZ4   9
 DEHA0G07095g   Debaryomyces hansenii CBS767 CAG90288.1 Q6BIZ4   22
Top


Last update: 2018-11-20 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille