Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (11393); Uniprot accession (1922); PDB accession (208); 3D entries (73); cryst (0)
All (10017) Archaea (67) Bacteria (7846) Eukaryota (1982) Viruses (5) unclassified (117) Structure (73) Characterized (547)
| 1 | ... | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 exo-β-1,3-glucanase (Exg1;WaEXG1)   Wickerhamomyces anomalus BS91 AFK33200.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BS91 AFK33203.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2) 3.2.1.58 Wickerhamomyces anomalus K / NCYC 432 CAA11018.1 O93983   9
 WAN_9541   Wickerhamomyces anomalus NRRL Y-366 AEZ66638.1     9
 WAN_6658   Wickerhamomyces anomalus NRRL Y-366 AEZ66635.1     9
 WAN_362   Wickerhamomyces anomalus NRRL Y-366 AEZ66636.1     9
 WAN_2708   Wickerhamomyces anomalus NRRL Y-366 AEZ66637.1     9
 WAN_5696   Wickerhamomyces anomalus NRRL Y-366 AEZ66639.1     49
 WAN_7786   Wickerhamomyces anomalus NRRL Y-366 AEZ66642.1     49
 WAN_7517   Wickerhamomyces anomalus NRRL Y-366 AEZ66640.1     12
 WAN_7540   Wickerhamomyces anomalus NRRL Y-366 AEZ66641.1     12
 exo-1,3-β-glucanase (Exg1;PaEXG1)   Wickerhamomyces anomalus WRL-076 AGC67021.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2)   Wickerhamomyces anomalus YF07b ABK40520.1 A0MPR7   9
 exo-β-1,3-glucanase (Exg1;WsExg1) 3.2.1.58 Williopsis saturnus WC91-2 ACP74152.2
ACP74152.1
C3VMY4   9
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97258.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CDZ96181.1     50
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CDZ97301.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CED85016.1     12
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ98740.1     50
 endoglucanase family 5 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97041.1     22
 exo-b--glucanase (fragment)   Xanthophyllomyces dendrorhous CDZ97418.1     9
 E   Xanthophyllomyces dendrorhous CED85254.1     9
 YALI0E34155g   Yarrowia lipolytica CLIB122 CAG80367.1 Q6C3K1   49
 YALI0F05390g (Exg1;YlExg1)   Yarrowia lipolytica CLIB122 CAG77837.1
CAA86952.1
Q12725   9
 YALI0E06149g   Yarrowia lipolytica CLIB122 CAG79198.1 Q6C6U5   12
 YALI0B11418g   Yarrowia lipolytica CLIB122 CAG83006.1 Q6CF03   12
 YALI1_E40502g   Yarrowia lipolytica CLIB89(W29) AOW06372.1     49
 YALI1_B15151g   Yarrowia lipolytica CLIB89(W29) AOW01550.1     12
 YALI1_F08075g   Yarrowia lipolytica CLIB89(W29) AOW06699.1     9
 YALI1_E07471g   Yarrowia lipolytica CLIB89(W29) AOW05030.1     12
 unknown   Zea mays ACG40334.1 B6TTA1   14
 unknown   Zea mays ACG41070.1
ACL54560.1
B6TVD7   7
 unknown (fragment)   Zea mays ACG41765.1     7
 unknown (fragment)   Zea mays ACG42458.1     11
 unknown (frameshift)   Zea mays ACG42480.1     7
 unknown (fragment)   Zea mays ACG45164.1     11
 unknown (fragment)   Zea mays B73 ACN33740.1
ACL52784.1
B7ZXY5
C0PEX4
  7
 unknown   Zea mays B73 ACN33727.1 C0PEW1   7
 unknown (ZM_BFb0114N09)   Zea mays B73 ACF78505.1
ACN30643.1
B4F8R2   7
 unknown (ZM_BFc0007C01)   Zea mays B73 ACF79301.1 B4FB08   11
 unknown (ZM_BFb0085A03)   Zea mays B73 ACF80825.1
ACN33507.1
B4FFD2   11
 unknown (ZM_BFc0066N17) (fragment)   Zea mays B73 ACF85134.1 B4FSP1   11
 unknown (ZM_BFc0070G19)   Zea mays B73 ACF85192.1
ACG23910.1
ACN27949.1
ACN28477.1
ACN34624.1
ACN34788.1
CAW50876.1
CBC20350.1
B4FSU9   11
 unknown (ZM_BFb0224N18) (fragment)   Zea mays B73 ACF87421.1 B4FZ78   14
 unknown (ZM_BFc0049D02)   Zea mays B73 ACF87838.1 B4F8R2   7
 ORF   Zea nicaraguensis AIZ06017.1     11
 BN860_03136g   Zygosaccharomyces bailii CLIB 213 CDF88136.1     12
 BN860_03928g   Zygosaccharomyces bailii CLIB 213 CDF88171.1     9
 BN860_06040g   Zygosaccharomyces bailii CLIB 213 CDF88266.1     49
 BN860_10352g   Zygosaccharomyces bailii CLIB 213 CDF89151.1     9
 BZL39_H01260 (Zpar0h01260_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ14753.1     12
 BZL39_E04630 (Zpar0e04630_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13124.1     49
 BZL39_A04270 (Zpar0a04270_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ09492.1     49
 BZL39_E05940 (Zpar0e05940_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13254.1     12
 BZL39_M01490 (Zpar0m01490_N) (fragment)   Zygosaccharomyces parabailii ATCC 60483 AQZ17593.1     9
 BZL39_E05580 (Zpar0e05580_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13219.1     9
 BZL39_A03310 (Zpar0a03310_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ09396.1     9
 BZL39_J01350 (Zpar0j01350_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ15967.1     9
 ZYRO0D15004g   Zygosaccharomyces rouxii CBS 732 CAR28149.1     9
 ZYRO0D15092g   Zygosaccharomyces rouxii CBS 732 CAR28152.1     12
 ZYRO0F01364g   Zygosaccharomyces rouxii CBS 732 CAR28323.1     49
 ZYRO0G15884g   Zygosaccharomyces rouxii CBS 732 CAR29738.1     9
 ZT1A5_G384   Zymoseptoria tritici ST99CH_1A5 SMY18949.1     9
 ZT1A5_G1136   Zymoseptoria tritici ST99CH_1A5 SMY19701.1     9
 ZT1A5_G4460   Zymoseptoria tritici ST99CH_1A5 SMY23020.1    
 ZT1A5_G137   Zymoseptoria tritici ST99CH_1A5 SMY18702.1     9
 ZT1A5_G5526 (fragment)   Zymoseptoria tritici ST99CH_1A5 SMY24085.1     22
 ZT1A5_G7597   Zymoseptoria tritici ST99CH_1A5 SMY26155.1     16
 ZT1A5_G5878   Zymoseptoria tritici ST99CH_1A5 SMY24437.1     49
 ZT1A5_G5542   Zymoseptoria tritici ST99CH_1A5 SMY24101.1     16
 ZT1A5_G10266   Zymoseptoria tritici ST99CH_1A5 SMY28820.1     12
 ZT1A5_G3200 (fragment)   Zymoseptoria tritici ST99CH_1A5 SMY21762.1     24
 ZT3D7_G145   Zymoseptoria tritici ST99CH_3D7 SMQ45001.1     9
 ZT3D7_G5593   Zymoseptoria tritici ST99CH_3D7 SMQ50440.1     16
 ZT3D7_G4474   Zymoseptoria tritici ST99CH_3D7 SMQ49323.1    
 ZT3D7_G7672   Zymoseptoria tritici ST99CH_3D7 SMQ52519.1     16
 ZT3D7_G5575 (fragment)   Zymoseptoria tritici ST99CH_3D7 SMQ50422.1     22
 ZT3D7_G1168   Zymoseptoria tritici ST99CH_3D7 SMQ46023.1     9
 ZT3D7_G377   Zymoseptoria tritici ST99CH_3D7 SMQ45233.1     9
 ZT3D7_G3218 (fragment)   Zymoseptoria tritici ST99CH_3D7 SMQ48069.1     24
 ZT3D7_G10310   Zymoseptoria tritici ST99CH_3D7 SMQ55155.1     12
 ZT3D7_G5923   Zymoseptoria tritici ST99CH_3D7 SMQ50770.1     49
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