Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (11921); Uniprot accession (1922); PDB accession (209); 3D entries (74); cryst (0)
All (10543) Archaea (67) Bacteria (8307) Eukaryota (2044) Viruses (5) unclassified (120) Structure (74) Characterized (547)
| 1 | ... | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 VIGAN_09149100 (Vigan.09g149100)   Vigna angularis var. angularis BAT97907.1     11
 VIGAN_10160100 (Vigan.10g160100)   Vigna angularis var. angularis BAU00044.1     7
 VIGAN_06132000 (Vigan.06g132000)   Vigna angularis var. angularis BAT90136.1     7
 VIGAN_06158400 (Vigan.06g158400)   Vigna angularis var. angularis BAT90354.1     11
 VIGAN_01093100 (Vigan.01g093100)   Vigna angularis var. angularis BAT73448.1     11
 VIGAN_03283600 (Vigan.03g283600)   Vigna angularis var. angularis BAT82775.1     7
 VIGAN_UM166800 (Vigan.umg166800) (fragment)   Vigna angularis var. angularis BAU03734.1     11
 VIGAN_02034400 (Vigan.02g034400)   Vigna angularis var. angularis BAT77749.1     7
 VIGAN_01135500 (Vigan.01g135500) (fragment)   Vigna angularis var. angularis BAT73817.1     11
 VIGAN_04376600 (Vigan.04g376600)   Vigna angularis var. angularis BAT86142.1     7
 VIGAN_03283800 (Vigan.03g283800) (fragment)   Vigna angularis var. angularis BAT82777.1     7
 VIGAN_03157600 (Vigan.03g157600)   Vigna angularis var. angularis BAT81736.1     14
 VIGAN_04421400 (Vigan.04g421400)   Vigna angularis var. angularis BAT86547.1     14
 VIGAN_01093300 (Vigan.01g093300) (fragment)   Vigna angularis var. angularis BAT73449.1     11
 VIGAN_01084100 (Vigan.01g084100)   Vigna angularis var. angularis BAT73366.1     14
 VIGAN_03157700 (Vigan.03g157700) (fragment)   Vigna angularis var. angularis BAT81737.1     14
 VIGAN_04114500 (Vigan.04g114500)   Vigna angularis var. angularis BAT83903.1     7
 VIGAN_04380200 (Vigan.04g380200)   Vigna angularis var. angularis BAT86176.1     7
 ORF (fragment)   Vitis riparia AAS00040.1 Q6R4Q6  
 VITISV_020441 (short fragment)   Vitis vinifera CAN62216.1 A5C9G4   7
 VITISV_015565 (short fragment)   Vitis vinifera CAN71607.1 A5AS93   7
 VITISV_000586   Vitis vinifera CAN74231.1 A5B782   14
 VITISV_020726 (fragment)   Vitis vinifera CAN70632.1 A5BWB8   7
 VITISV_023481 (short fragment)   Vitis vinifera CAN71993.1 A5AS93   7
 VITISV_023482 (short fragment)   Vitis vinifera CAN71994.1 A5B3T1   7
 VITISV_023484   Vitis vinifera CAN71995.1 A5B3T2   7
 VITISV_016766 + VITISV_016765 (fragments)   Vitis vinifera CAN78585.1
CAN78586.1
    14
 VITISV_033630   Vitis vinifera CAN77937.1 A5AHI3   7
 EgL (fragment)   Volvariella bombycina AEQ58920.1     5
 endoglucanase I (EG1;EGI) 3.2.1.4 Volvariella volvacea V14 AAG59832.1
AEQ58914.1
Q9C3Z8   5
 endoglucanase I (EgI;NCel5A) (Cel5A) 3.2.1.4 Volvariella volvacea WX32 ACE06751.1     5
 exo-β-1,3-glucanase   Wickerhamomyces anomalus ARX76274.1     9
 exo-β-1,3-glucanase (Exg1;PaEXG1;WaEXG1)   Wickerhamomyces anomalus CAA05243.1 H6UWP0
O93939
  9
 exo-1,3-β-glucanase (Exg2;PaEXG2)   Wickerhamomyces anomalus AGC67022.1     9
 exo-β-1,3-glucanase (Exg1)   Wickerhamomyces anomalus AS F17.12 CDF77670.1     9
 exo-β-1,3-glucanase (Exg2)   Wickerhamomyces anomalus AS F17.12 CDF77671.1     9
 exo-β-1,3-glucanase (Exg2)   Wickerhamomyces anomalus AS1 CDH93665.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BCA15 AFK33204.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1) (fragment)   Wickerhamomyces anomalus BCA15 AFK33201.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1)   Wickerhamomyces anomalus BCU24 AFK33202.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BCU24 AFK33205.1     9
 exo-β-1,3-glucanase (Exg1;WaEXG1)   Wickerhamomyces anomalus BS91 AFK33200.1     9
 exo-β-1,3-glucanase (Exg2;WaEXG2)   Wickerhamomyces anomalus BS91 AFK33203.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2) 3.2.1.58 Wickerhamomyces anomalus K / NCYC 432 CAA11018.1 O93983   9
 WAN_9541   Wickerhamomyces anomalus NRRL Y-366 AEZ66638.1     9
 WAN_6658   Wickerhamomyces anomalus NRRL Y-366 AEZ66635.1     9
 WAN_362   Wickerhamomyces anomalus NRRL Y-366 AEZ66636.1     9
 WAN_2708   Wickerhamomyces anomalus NRRL Y-366 AEZ66637.1     9
 WAN_5696   Wickerhamomyces anomalus NRRL Y-366 AEZ66639.1     49
 WAN_7786   Wickerhamomyces anomalus NRRL Y-366 AEZ66642.1     49
 WAN_7517   Wickerhamomyces anomalus NRRL Y-366 AEZ66640.1     12
 WAN_7540   Wickerhamomyces anomalus NRRL Y-366 AEZ66641.1     12
 exo-1,3-β-glucanase (Exg1;PaEXG1)   Wickerhamomyces anomalus WRL-076 AGC67021.1     9
 exo-β-1,3-glucanase (Exg2;PaEXG2;WaEXG2)   Wickerhamomyces anomalus YF07b ABK40520.1 A0MPR7   9
 exo-β-1,3-glucanase (Exg1;WsExg1) 3.2.1.58 Williopsis saturnus WC91-2 ACP74152.2
ACP74152.1
C3VMY4   9
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97258.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CDZ96181.1     50
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CDZ97301.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CED85016.1     12
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ98740.1     50
 endoglucanase family 5 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97041.1     22
 exo-b--glucanase (fragment)   Xanthophyllomyces dendrorhous CDZ97418.1     9
 E   Xanthophyllomyces dendrorhous CED85254.1     9
 YALI0E34155g   Yarrowia lipolytica CLIB122 CAG80367.1 Q6C3K1   49
 YALI0F05390g (Exg1;YlExg1)   Yarrowia lipolytica CLIB122 CAG77837.1
CAA86952.1
Q12725   9
 YALI0E06149g   Yarrowia lipolytica CLIB122 CAG79198.1 Q6C6U5   12
 YALI0B11418g   Yarrowia lipolytica CLIB122 CAG83006.1 Q6CF03   12
 YALI1_E40502g   Yarrowia lipolytica CLIB89(W29) AOW06372.1     49
 YALI1_B15151g   Yarrowia lipolytica CLIB89(W29) AOW01550.1     12
 YALI1_F08075g   Yarrowia lipolytica CLIB89(W29) AOW06699.1     9
 YALI1_E07471g   Yarrowia lipolytica CLIB89(W29) AOW05030.1     12
 unknown   Zea mays ACG40334.1 B6TTA1   14
 unknown   Zea mays ACG41070.1
ACL54560.1
B6TVD7   7
 unknown (fragment)   Zea mays ACG41765.1     7
 unknown (fragment)   Zea mays ACG42458.1     11
 unknown (frameshift)   Zea mays ACG42480.1     7
 unknown (fragment)   Zea mays ACG45164.1     11
 unknown (fragment)   Zea mays B73 ACN33740.1
ACL52784.1
B7ZXY5
C0PEX4
  7
 unknown   Zea mays B73 ACN33727.1 C0PEW1   7
 unknown (ZM_BFb0114N09)   Zea mays B73 ACF78505.1
ACN30643.1
B4F8R2   7
 unknown (ZM_BFc0007C01)   Zea mays B73 ACF79301.1 B4FB08   11
 unknown (ZM_BFb0085A03)   Zea mays B73 ACF80825.1
ACN33507.1
B4FFD2   11
 unknown (ZM_BFc0066N17) (fragment)   Zea mays B73 ACF85134.1 B4FSP1   11
 unknown (ZM_BFc0070G19)   Zea mays B73 ACF85192.1
ACG23910.1
ACN27949.1
ACN28477.1
ACN34624.1
ACN34788.1
CAW50876.1
CBC20350.1
B4FSU9   11
 unknown (ZM_BFb0224N18) (fragment)   Zea mays B73 ACF87421.1 B4FZ78   14
 unknown (ZM_BFc0049D02)   Zea mays B73 ACF87838.1 B4F8R2   7
 ORF   Zea nicaraguensis AIZ06017.1     11
 BN860_03136g   Zygosaccharomyces bailii CLIB 213 CDF88136.1     12
 BN860_03928g   Zygosaccharomyces bailii CLIB 213 CDF88171.1     9
 BN860_06040g   Zygosaccharomyces bailii CLIB 213 CDF88266.1     49
 BN860_10352g   Zygosaccharomyces bailii CLIB 213 CDF89151.1     9
 BZL39_H01260 (Zpar0h01260_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ14753.1     12
 BZL39_E04630 (Zpar0e04630_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13124.1     49
 BZL39_A04270 (Zpar0a04270_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ09492.1     49
 BZL39_E05940 (Zpar0e05940_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13254.1     12
 BZL39_M01490 (Zpar0m01490_N) (fragment)   Zygosaccharomyces parabailii ATCC 60483 AQZ17593.1     9
 BZL39_E05580 (Zpar0e05580_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13219.1     9
 BZL39_A03310 (Zpar0a03310_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ09396.1     9
 BZL39_J01350 (Zpar0j01350_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ15967.1     9
 ZYRO0D15004g   Zygosaccharomyces rouxii CBS 732 CAR28149.1     9
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