Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (14323); Uniprot accession (1922); PDB accession (218); 3D entries (77); cryst (0)
All (12930) Archaea (94) Bacteria (10492) Eukaryota (2215) Viruses (8) unclassified (121) Structure (77) Characterized (551)
| 1 | ... | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | ... | 105 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 ORF (fragment)   uncultured bacterium AGO64720.1     4
 ORF (fragment)   uncultured bacterium AGO64721.1     4
 ORF (fragment)   uncultured bacterium AGO64733.1     4
 ORF (fragment)   uncultured bacterium AGW24153.1
ANN23772.1
ANN23773.1
ANN23774.1
ANN23775.1
    4
 ORF (fragment)   uncultured bacterium AGW24154.1     4
 ORF (fragment)   uncultured bacterium AGW24155.1     4
 ORF (fragment)   uncultured bacterium AGW24156.1     4
 endo-β-1,4-glucanase (Endos11)   uncultured bacterium AGW99967.1     2
 endo-β-1,4-glucanase (Endos9)   uncultured bacterium AGW99965.1     2
 endo-β-1,4-glucanase (Endos3)   uncultured bacterium AGW99959.1     2
 endo-β-1,4-glucanase (Endos15)   uncultured bacterium AGW99971.1     2
 endo-β-1,4-glucanase (Endos1)   uncultured bacterium AGW99957.1     2
 endo-β-1,4-glucanase (Endos19)   uncultured bacterium AGW99975.1     2
 endo-β-1,4-glucanase (Endos13)   uncultured bacterium AGW99969.1     2
 endo-β-1,4-glucanase (Endos7)   uncultured bacterium AGW99963.1     2
 endo-β-1,4-glucanase (Endos4)   uncultured bacterium AGW99960.1     2
 endo-β-1,4-glucanase (Endos10)   uncultured bacterium AGW99966.1     2
 endo-β-1,4-glucanase (Endos18)   uncultured bacterium AGW99974.1     2
 endo-β-1,4-glucanase (Endos2)   uncultured bacterium AGW99958.1     2
 endo-β-1,4-glucanase (Endos20)   uncultured bacterium AGW99976.1     2
 endo-β-1,4-glucanase (Endos8)   uncultured bacterium AGW99964.1     2
 endo-β-1,4-glucanase (Endos16)   uncultured bacterium AGW99972.1     2
 endo-β-1,4-glucanase (Endos6)   uncultured bacterium AGW99962.1     2
 endo-β-1,4-glucanase (Endos12)   uncultured bacterium AGW99968.1     2
 endo-β-1,4-glucanase (Endos5)   uncultured bacterium AGW99961.1     2
 endo-β-1,4-glucanase (Endos14)   uncultured bacterium AGW99970.1     2
 endo-β-1,4-glucanase (Endos17)   uncultured bacterium AGW99973.1     2
 cellulase (CelE1) 3.2.1.4 uncultured bacterium AHA42547.2
AHA42547.1
  4M1R[A,B] 2
 endo-β-1,4-mannosidase (ManEM1) 3.2.1.- uncultured bacterium AHC00282.1     7
 mannosidase (fragment)   uncultured bacterium AGG23326.1     7
 cellulase   uncultured bacterium BAO65790.1     2
 endoglucanase   uncultured bacterium BAO65795.1     2
 cellulase   uncultured bacterium BAO65801.1     2
 endoglucanase   uncultured bacterium BAO65799.1     5
 ORF   uncultured bacterium BAO65808.1     25
 ORF (fragment)   uncultured bacterium ABS59464.1
ABS59408.1
ABS59409.1
ABS59410.1
ABS59412.1
ABS59421.1
ABS59422.1
ABS59425.1
ABS59427.1
ABS59428.1
ABS59432.1
ABS59434.1
ABS59436.1
ABS59438.1
ABS59439.1
ABS59441.1
ABS59444.1
ABS59445.1
ABS59446.1
ABS59447.1
ABS59448.1
ABS59452.1
ABS59453.1
ABS59455.1
ABS59457.1
ABS59460.1
ABS59461.1
ABS59465.1
ABS59467.1
ABS59468.1
ABS59469.1
ABS59470.1
ABS59471.1
ABS59472.1
ABS59473.1
ABS59474.1
ABS59475.1
ABS59476.1
ABS59477.1
ABS59478.1
ABS59480.1
ABS59482.1
ABS59486.1
ABS59488.1
ABS59489.1
ABS59491.1
ABS59501.1
ABS59502.1
ABS59503.1
ABS59504.1
ABS59505.1
ABS59511.1
ABS59513.1
ABS59519.1
ABS59528.1
ABS59529.1
ABS59530.1
ABS59533.1
ABS59536.1
ABS59537.1
ABS59538.1
ABS59539.1
ABS59540.1
ABS59542.1
ABS59544.1
ABS59546.1
ABS59548.1
ABS59552.1
ABS59554.1
ABS59555.1
ABS59558.1
ABS59561.1
ABS59563.1
ABS59567.1
ABS59571.1
ABS59572.1
ABS59573.1
ABS59574.1
ABS59575.1
ABS59576.1
ABS59577.1
ABS59581.1
ABS59583.1
ABS59584.1
ABS59585.1
ABS59588.1
ABS59591.1
ABS59592.1
ABS59593.1
ABS59598.1
ABS59599.1
ABS59600.1
ABS59602.1
ABS59604.1
ABS59609.1
ABS59610.1
ABS59611.1
ABS59612.1
ABS59613.1
ABS59614.1
ABS59615.1
ABS59617.1
ABS59618.1
ABS59619.1
ABS59623.1
ABS59624.1
ABS59625.1
ABS59626.1
ABS59627.1
ABS59628.1
ABS59629.1
ABS59630.1
ABS59631.1
ABS59634.1
ABS59635.1
ABS59638.1
ABS59640.1
ABS59641.1
ABS59642.1
ABS59644.1
ABS59645.1
ABS59646.1
ABS59648.1
ABS59649.1
ABS59651.1
A7L6E6
A7L6K2
 
 ORF (fragment)   uncultured bacterium ABS59411.1
ABS59414.1
ABS59459.1
ABS59499.1
ABS59500.1
ABS59507.1
ABS59516.1
ABS59517.1
ABS59520.1
ABS59525.1
ABS59541.1
ABS59543.1
ABS59545.1
ABS59549.1
ABS59559.1
ABS59568.1
ABS59569.1
ABS59616.1
A7L6E9  
 ORF (fragment)   uncultured bacterium ABS59413.1
ABS59418.1
ABS59435.1
ABS59442.1
ABS59456.1
ABS59458.1
ABS59463.1
ABS59578.1
ABS59636.1
A7L6F1  
 ORF (fragment)   uncultured bacterium ABS59415.1
ABS59417.1
ABS59426.1
ABS59437.1
ABS59454.1
A7L6F3  
 ORF (fragment)   uncultured bacterium ABS59416.1
ABS59419.1
ABS59420.1
ABS59423.1
ABS59424.1
ABS59429.1
ABS59431.1
ABS59433.1
ABS59440.1
ABS59443.1
ABS59449.1
ABS59450.1
ABS59451.1
ABS59462.1
ABS59466.1
ABS59479.1
ABS59481.1
ABS59484.1
ABS59485.1
ABS59487.1
ABS59495.1
ABS59551.1
ABS59579.1
ABS59580.1
ABS59586.1
ABS59587.1
ABS59589.1
ABS59590.1
ABS59594.1
ABS59596.1
ABS59597.1
ABS59603.1
ABS59605.1
ABS59606.1
ABS59620.1
ABS59621.1
ABS59622.1
ABS59632.1
ABS59633.1
ABS59637.1
ABS59639.1
ABS59643.1
ABS59647.1
ABS59650.1
ABS59652.1
A7L6F4  
 ORF (fragment)   uncultured bacterium ABS59430.1
ABS59483.1
ABS59490.1
ABS59492.1
ABS59493.1
ABS59494.1
ABS59497.1
ABS59506.1
ABS59508.1
ABS59510.1
ABS59512.1
ABS59515.1
ABS59518.1
ABS59523.1
ABS59524.1
ABS59526.1
ABS59527.1
ABS59531.1
ABS59532.1
ABS59534.1
ABS59535.1
ABS59547.1
ABS59556.1
ABS59557.1
ABS59562.1
ABS59565.1
ABS59570.1
ABS59582.1
ABS59601.1
ABS59607.1
ABS59608.1
A7L6G8  
 ORF (fragment)   uncultured bacterium ABS59496.1
ABS59550.1
A7L6N4  
 ORF (fragment)   uncultured bacterium ABS59498.1
ABS59521.1
ABS59522.1
A7L6N6  
 ORF (fragment)   uncultured bacterium ABS59509.1
ABS59514.1
ABS59553.1
A7L6P7  
 ORF (fragment)   uncultured bacterium ABS59560.1 A7L6U8  
 ORF (fragment)   uncultured bacterium ABS59564.1 A7L6V2  
 ORF (fragment)   uncultured bacterium ABS59566.1 A7L6V4  
 ORF (fragment)   uncultured bacterium ABS59595.1 A7L6Y3  
 endoglucanase (CellMM5.1;Cell5.1_3) 3.2.1.4 uncultured bacterium AID57617.1     25
 4348GL1_005 (fragment)   uncultured bacterium ABW39332.1 A9LDS6   52
 4348GL13_002 / 4348GL9_002   uncultured bacterium ABW39333.1
ABW39340.1
A9LDS7   4
 4348GL14_002   uncultured bacterium ABW39334.1 A9LDS8   4
 4348GL2_002   uncultured bacterium ABW39335.1 A9LDS9   4
 4348GL29_002   uncultured bacterium ABW39336.1 A9LDT0   2
 4348GL29_006   uncultured bacterium ABW39337.1 A9LDT1   2
 4348GL5_001   uncultured bacterium ABW39338.1 A9LDT2   4
 4348GL6_003   uncultured bacterium ABW39339.1 A9LDT3   4
 4348JG16_002 (fragment)   uncultured bacterium ABW39341.1 A9LDT5  
 4348JG21_002   uncultured bacterium ABW39342.1 A9LDT6   2
 4348JG23_005 (fragment)   uncultured bacterium ABW39343.1 A9LDT7   4
 4348JG24_006   uncultured bacterium ABW39344.1 A9LDT8   4
 4348JG28_001 3.2.1.- uncultured bacterium ABW39345.1 A9LDT9   52
 4348JG30_004   uncultured bacterium ABW39346.1 A9LDU0  
 4348JG36_001   uncultured bacterium ABW39347.1 A9LDU1   4
 4348JG38_003   uncultured bacterium ABW39348.1 A9LDU2   4
 4348JG39_003   uncultured bacterium ABW39349.1 A9LDU3   4
 4348JG42_001   uncultured bacterium ABW39350.1 A9LDU4   2
 4348JG48_005 3.2.1.- uncultured bacterium ABW39351.1 A9LDU5   52
 4399GL12_002   uncultured bacterium ABW39352.1 A9LDU6  
 4399GL12_004   uncultured bacterium ABW39353.1 A9LDU7  
 4399GL19_002   uncultured bacterium ABW39354.1 A9LDU8  
 4399GL23_006   uncultured bacterium ABW39355.1 A9LDU9   2
 4399GL43_001   uncultured bacterium ABW39356.1 A9LDV0   2
 4399GL44_001   uncultured bacterium ABW39357.1 A9LDV1   2
 4399GL47_001   uncultured bacterium ABW39358.1 A9LDV2   2
 4399GL7_002 (fragment)   uncultured bacterium ABW39359.1 A9LDV3  
 4399GL7_004   uncultured bacterium ABW39360.1 A9LDV4  
 399GL9_003   uncultured bacterium ABW39361.1 A9LDV5  
 ORF   uncultured bacterium A2_10 AEW47942.1     25
 ORF (fragment)   uncultured bacterium Ad_010_C07 AIF25909.1     4
 ORF (fragment)   uncultured bacterium Ad_010_C07 AIF25910.1     4
 ORF   uncultured bacterium Ad_087_C16_contig1 AIF25923.1     4
 ORF   uncultured bacterium Ad_087_C16_contig1 AIF25922.1     4
 ORF (fragment)   uncultured bacterium Ad_091_F22_contig1 AIF25943.1     46
 ORF   uncultured bacterium Ad_091_F22_contig1 AIF25951.1     4
 ORF (fragment)   uncultured bacterium Ad_095_K16_contig2 AIF25975.1     4
 ORF (fragment)   uncultured bacterium Ad_095_K16_contig2 AIF25967.1     46
 ORF   uncultured bacterium Ad_113_F04_contig2 AIF25991.1     2
 ORF   uncultured bacterium Ad_113_I18_contig2 AIF26005.1     4
 ORF   uncultured bacterium Ad_125_D08 AIF26053.1     2
 ORF   uncultured bacterium Ad_136_J17_contig1 AIF26090.1     4
 ORF   uncultured bacterium Ad_143_A19 AIF26140.1     2
 ORF   uncultured bacterium Ad_143_D13_contig1 AIF26172.1     2
 ORF   uncultured bacterium Ad_144_C12_contig2 AIF26213.1     2
 ORF (fragment)   uncultured bacterium Ad_150_H18 AIF26216.1     2
 B1_GH5   uncultured bacterium B1_8 AEW47944.1     25
 B2_GH5   uncultured bacterium B2_18 AEW47949.1     25
 ORF   uncultured bacterium contig00103(2014) AIA99600.1     46
 ORF   uncultured bacterium contig00110(2014) AIA99611.1     46
 ORF   uncultured bacterium Contig1468_n_1482_cl AHF26427.1     37
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