Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (14935); Uniprot accession (1921); PDB accession (224); 3D entries (78); cryst (0)
All (13534) Archaea (95) Bacteria (11085) Eukaryota (2219) Viruses (8) unclassified (127) Structure (78) Characterized (563)
| 1 | ... | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | ... | 111 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 SVEN_6970   Streptomyces venezuelae ATCC 10712 CCA60256.1     2
 SVEN_6902 (fragment)   Streptomyces venezuelae ATCC 10712 CCA60188.1    
 SVEN_6905   Streptomyces venezuelae ATCC 10712 CCA60191.1     8
 BN2537_5981   Streptomyces venezuelae ATCC 15439 CUM38508.1    
 BN2537_1935   Streptomyces venezuelae ATCC 15439 CUM36485.1     2
 BN2537_14531   Streptomyces venezuelae ATCC 15439 CUM42783.1     18
 BN2537_16313   Streptomyces venezuelae ATCC 15439 CUM43674.1     51
 BN2537_1569   Streptomyces venezuelae ATCC 15439 CUM36302.1     51
 BN2537_3229   Streptomyces venezuelae ATCC 15439 CUM37132.1     40
 AQF52_7445   Streptomyces venezuelae ATCC 15439 ALO13031.1     51
 AQF52_5395   Streptomyces venezuelae ATCC 15439 ALO10989.1    
 AQF52_7272   Streptomyces venezuelae ATCC 15439 ALO12858.1     2
 AQF52_6684   Streptomyces venezuelae ATCC 15439 ALO12277.1     40
 AQF52_0493   Streptomyces venezuelae ATCC 15439 ALO06091.1     51
 AQF52_1325   Streptomyces venezuelae ATCC 15439 ALO06921.1     18
 SVTN_01005   Streptomyces vietnamensis GIM4.0001 AJF63299.1     4
 SVTN_25570   Streptomyces vietnamensis GIM4.0001 AJF67246.1    
 SVTN_32840   Streptomyces vietnamensis GIM4.0001 AJF70118.1     40
 B1H20_29330   Streptomyces violaceoruber S21 ARF65053.1     2
 B1H20_24815   Streptomyces violaceoruber S21 ARF64240.1    
 Strvi_3247   Streptomyces violaceusniger Tu 4113 AEM82935.1     19
 Strvi_4282   Streptomyces violaceusniger Tu 4113 AEM83933.1     43
 Strvi_5490   Streptomyces violaceusniger Tu 4113 AEM85012.1     8
 Strvi_8131   Streptomyces violaceusniger Tu 4113 AEM87454.1     40
 Strvi_8930   Streptomyces violaceusniger Tu 4113 AEM88231.1     1
 Strvi_3249   Streptomyces violaceusniger Tu 4113 AEM82937.1     51
 SXIM_41680   Streptomyces xiamenensis 318 AKG45552.1    
 SXIM_49970   Streptomyces xiamenensis 318 AKG46381.1     4
 SXIM_49310   Streptomyces xiamenensis 318 AKG46315.1     8
 SXIM_16110   Streptomyces xiamenensis 318 AKG42995.1     2
 Sros_0934   Streptosporangium roseum DSM 43021 ACZ83938.1 D2B807   8
 Sros_1713   Streptosporangium roseum DSM 43021 ACZ84704.1 D2AS25   28
 Sros_5000   Streptosporangium roseum DSM 43021 ACZ87799.1 D2B8I9   18
 Sros_5302   Streptosporangium roseum DSM 43021 ACZ88069.1 D2BC46   43
 DKM19_18775   Streptosporangium sp. caverna AWS43115.1     22
 DKM19_10005   Streptosporangium sp. caverna AWS41636.1     22
 DKM19_02670   Streptosporangium sp. caverna AWS40401.1     1
 DKM19_02655   Streptosporangium sp. caverna AWS40398.1     8
 BXT84_03210   Sulfobacillus thermotolerans Kr AUW93080.1     19
 SCL_1792   Sulfuricaulis limicola HA5 BAV34090.1     1
 NIES970_21890   Synechococcus sp. NIES-970 BAW97238.1     39
 Syn6312_0711   Synechococcus sp. PCC 6312 AFY59930.1     39
 Sgly_1611   Syntrophobotulus glycolicus DSM 8271 ADY55909.1     25
 Swol_1899   Syntrophomonas wolfei subsp. wolfei str. Goettingen G311 ABI69196.1 Q0AVQ8  
 Slip_0761   Syntrophothermus lipocalidus DSM 12680 ADI01541.1 D7CLF6  
 C1A40_07415   Tamlana sp. UJ94 AUS05313.1     5
 C1A40_02195   Tamlana sp. UJ94 AUS04354.1     4
 BCB71_04995   Tannerella sp. oral taxon HOT-286 str. W11667 AOH40543.1    
 C7123_12510   Tannerella sp. oral taxon HOT-286 W11666 AVV54443.1    
 LMI_2047   Tatlockia micdadei ATCC33218 CEG61331.1    
 B6N58_05815   Tatlockia micdadei NZ2015 ARG97215.1    
 B6V88_08870   Tatlockia micdadei NZ2016 ARH00527.1    
 AUW17_07165   Tenacibaculum dicentrarchi AY7486TD ALU76135.1     42
 TJEJU_2824   Tenacibaculum jejuense KCTC 22618 SNR16498.1     42
 TJEJU_3613   Tenacibaculum jejuense KCTC 22618 SNR17256.1     7
 TJEJU_1866   Tenacibaculum jejuense KCTC 22618 SNR15572.1     10
 TJEJU_1423   Tenacibaculum jejuense KCTC 22618 SNR15156.1     2
 TJEJU_3612   Tenacibaculum jejuense KCTC 22618 SNR17255.1     1
 TJEJU_3611   Tenacibaculum jejuense KCTC 22618 SNR17254.1    
 MARIT_1799   Tenacibaculum maritimum SFZ82884.1     42
 D6200_02495   Tenacibaculum mesophilum DSM 13764 AZJ31499.1     42
 BTO06_08825   Tenacibaculum sp. SZ-18 AUC15234.1     42
 BK010_08440   Tenericutes bacterium MO-XQ AUD63616.1    
 BK010_08950   Tenericutes bacterium MO-XQ AUD63710.1    
 BK011_08735   Tenericutes bacterium MZ-XQ AUD65764.1    
 glycosyl hydrolase family 5_53 domain-containing protein   Teredinibacter sp. Bs02 AIF91557.1     53
 glycosyl hydrolase family 5_8 and glycosyl hydrolase family 6 domain-containing protein   Teredinibacter sp. Bs02 AIF91556.1     8
 bifunctional beta 1,4-endoglucanase/cellobiohydrolase, partial (CelaB) (fragment)   Teredinibacter turnerae PMS-1675L.S.0a.01 ARD05454.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-509L.S.1a.4 AHL25053.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-509L.S.1a.6 AHL25054.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-517Y.S.1a.10 AHL25051.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-535T.S.1b.3 AHL25050.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-539Y.S.1a.1 AHL25035.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-554M.S.1a.4 AHL25043.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-574K.S.1a.1 AHL25044.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-683H.S.1a.9 AHL25049.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae PMS-691W.S.1a.3 AHL25052.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T0609 AHL25040.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T0611 AHL25041.1     2
 TERTU_2895 (CelA)   Teredinibacter turnerae T7901 ACR12145.1 C5BNA9   2
 TERTU_3565   Teredinibacter turnerae T7901 ACR11017.1 C5BRI4   1
 TERTU_4344   Teredinibacter turnerae T7901 ACR11348.1 C5BIG0   8
 TERTU_0183   Teredinibacter turnerae T7901 ACR12128.1 C5BLG4   26
 TERTU_4415   Teredinibacter turnerae T7901 ACR14510.1 C5BJ14   7
 TERTU_3751   Teredinibacter turnerae T7901 ACR11279.1 C5BSD2  
 TERTU_3361   Teredinibacter turnerae T7901 ACR12247.1 C5BQM3   4
 TERTU_0428   Teredinibacter turnerae T7901 ACR12792.1 C5BMU2   53
 TERTU_0427   Teredinibacter turnerae T7901 ACR13327.1 C5BMU1   53
 TERTU_3690   Teredinibacter turnerae T7901 ACR13782.1 C5BS75  
 TERTU_2894   Teredinibacter turnerae T7901 ACR13797.1 C5BNA8   8
 TERTU_4090   Teredinibacter turnerae T7901 ACR14317.1 C5BUE5   41
 TERTU_4085   Teredinibacter turnerae T7901 ACR14401.1 C5BUE0   47
 bifunctional β-1,4-endoglucanase / cellobiohydrolase (CelAB) 3.2.1.4
3.2.1.91
Teredinibacter turnerae T7901 ABS72374.1 A9Q634   2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T7902 AHL25042.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T7903 AHL25048.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8401 AHL25055.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8402 AHL25036.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8412 AHL25046.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8415 AHL25039.1     2
 bifunctional β-1,4-endoglucanase/cellobiohydrolase (CelaB) (fragment)   Teredinibacter turnerae T8503 AHL25045.1     2
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