Glycoside Hydrolase Family 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (11393); Uniprot accession (1922); PDB accession (208); 3D entries (73); cryst (0)
All (10017) Archaea (67) Bacteria (7846) Eukaryota (1982) Viruses (5) unclassified (117) Structure (73) Characterized (547)
| 1 | ... | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AW19_2483   Yersinia frederiksenii Y225 AJI87395.1     13
 CH53_3461   Yersinia intermedia Y228 AJJ21305.1     13
 DJ57_73   Yersinia kristensenii ATCC 33639 AIN17485.1     13
 CH54_3304   Yersinia kristensenii Y231 AJJ35271.1     13
 M486_2154   Yersinia pestis 1045 AKT02463.1     13
 M478_2212   Yersinia pestis 2944 AKS63812.1     13
 M477_3237   Yersinia pestis 790 AKS84007.1     13
 A1122_01260   Yersinia pestis A1122 AEL70935.1
AJJ73576.1
    13
 YPA_3393   Yersinia pestis Antiqua ABG15355.1
AJJ79602.1
Q1C2G7   13
 YPC_0794   Yersinia pestis biovar Medievalis str. Harbin 35 ADV97486.1     13
 YP3444   Yersinia pestis biovar Microtus str. 91001 AAS63604.1
NP_994727.1
    13
 BAY22_02465   Yersinia pestis Cadman ANW12914.1     13
 AK38_1817   Yersinia pestis CO92 AJJ90027.1     13
 YPD4_0658   Yersinia pestis D106004 ACY57567.1 D0JFL3   13
 YPD8_0658 (fragment)   Yersinia pestis D182038 ACY61348.1 D0JQ35   13
 CH61_3449   Yersinia pestis Dodson AJJ32882.1     13
 CH46_162   Yersinia pestis El Dorado AJJ16012.1     13
 CH55_3543   Yersinia pestis Harbin35 AJK07828.1     13
 CH62_3904   Yersinia pestis Java9 AJJ39389.1     13
 Y3438 (probable fragment)   Yersinia pestis KIM10+ AAM86987.1
NP_670736.1
    13
 CH44_2037   Yersinia pestis KIM5 AKB89791.1     13
 CH45_128   Yersinia pestis Nairobi AJK20368.1     13
 YPN_3196   Yersinia pestis Nepal516 ABG19523.1 Q1CEQ7   13
 CH63_1298   Yersinia pestis Nicholisk 41 AJJ45062.1     13
 CH59_1109   Yersinia pestis PBM19 AJI90819.1     13
 BZ15_2819   Yersinia pestis Shasta AJJ50222.1     13
 CH60_3341   Yersinia pestis str. Pestoides B AJK12567.1     13
 BZ23_2830   Yersinia pseudotuberculosis 1 AJJ71713.1     13
 DJ40_3168   Yersinia pseudotuberculosis ATCC 6904 AIN15627.1     13
 BZ20_2845   Yersinia pseudotuberculosis EP2/+ AJJ08646.1     13
 YpsIP31758_0708   Yersinia pseudotuberculosis IP 31758 ABS49253.1 A7FEL9   13
 YPTB3269   Yersinia pseudotuberculosis IP 32953 CAH22507.1     13
 BZ17_3341   Yersinia pseudotuberculosis IP 32953 AJJ55811.1     13
 BZ21_2549   Yersinia pseudotuberculosis MD67 AJJ02299.1     13
 YPTS_3405   Yersinia pseudotuberculosis PB1/+ ACC90360.1
AJJ66627.1
B2K1I7   13
 BZ19_2675   Yersinia pseudotuberculosis str. PA3606 AJK15186.1     13
 YPK_0780   Yersinia pseudotuberculosis YPIII ACA67081.1
AJJ57863.1
B1JMZ8   13
 CH64_1914   Yersinia rohdei YRA AJJ09410.1     13
 BF17_03365   Yersinia similis CCUG 52882 AHK18490.1     13
 AZF00_16475   Zhongshania aliphaticivorans SM2 AMO69798.1    
 zobellia_208 (EngA)   Zobellia galactanivorans DsiJT CAZ94281.1     4
 zobellia_2986   Zobellia galactanivorans DsiJT CAZ97132.1     42
 zobellia_3703 (BglC)   Zobellia galactanivorans DsiJT CAZ97841.1     2
 ZPR_1048   Zunongwangia profunda SM-A87 ADF51393.1 D5BI05   42
 ZPR_3478   Zunongwangia profunda SM-A87 ADF53794.1 D5BJU6  
 ZPR_4337   Zunongwangia profunda SM-A87 ADF54639.1 D5BB99   13
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