Glycoside Hydrolase Family 5 / Subf 8

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (355); Uniprot accession (76); PDB accession (10); 3D entries (6); cryst (0)
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 AHOG_12310 (Mana1)   Actinoalloteichus hoggarensis DSM 45943 ASO20105.1     8
 TL08_12195   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63253.1     8
 UA74_13020   Actinoalloteichus sp. ADI127-7 APU14662.1     8
 UA75_13100   Actinoalloteichus sp. GBA129-24 APU20630.1     8
 SAMN04489716_4311   Actinoplanes derwentensis DSM 43941 SDT52805.1     8
 SAMN04489716_3740   Actinoplanes derwentensis DSM 43941 SDT42643.1     8
 AFR_18915   Actinoplanes friuliensis DSM 7358 AGZ42057.1     8
 AMIS_23050   Actinoplanes missouriensis 431 BAL87525.1     8
 AMIS_40420   Actinoplanes missouriensis 431 BAL89262.1     8
 L083_5388   Actinoplanes sp. N902-109 AGL18898.1     8
 Amir_1830   Actinosynnema mirum DSM 43827 ACU35778.1 C6WE35   8
 Amir_4152   Actinosynnema mirum DSM 43827 ACU38007.1 C6WH88   8
 CNX65_20775   Actinosynnema pretiosum X47 ATE55417.1     8
 CNX65_09135   Actinosynnema pretiosum X47 ATE53439.1     8
 β-1,4-mannanase   Alicyclobacillus acidocaldarius AAT47714.1     8
 glycosyl hydrolase family 5_8 and glycosyl hydrolase family 6 domain-containing protein   Alteromonadaceae bacterium Bs02 AIF91556.1     8
 glycosyl hydrolase family 5_8 domain-containing protein, partial   Alteromonadaceae bacterium Bs08 AIF91546.1     8
 glycosyl hydrolase family 5_8 domain-containing protein   Alteromonadaceae bacterium Bs12 AIF91534.1     8
 AXY_08250   Amphibacillus xylanus NBRC 15112 BAM46957.1     8
 B737_7302   Amycolatopsis mediterranei RB AGT87963.1     8
 RAM_38105   Amycolatopsis mediterranei S699 AEK46088.1
AFO80835.1
    8
 AMED_7413   Amycolatopsis mediterranei U32 ADJ49127.1 D8I9G0   8
 SD37_16955   Amycolatopsis orientalis B-37 ANN17163.1     8
 β-mannanase   Bacillus circulans AAS48170.1 Q6QHT4   8
 β-mannanase (TM1) 3.2.1.78 Bacillus circulans AAT39478.1 Q6IUP2   8
 β-mannanase (Man1;ManB48) 3.2.1.78 Bacillus circulans CGMCC 1416 AAX87002.1 Q49HI4   8
 β-mannanase (Man5A) 3.2.1.78 Bacillus circulans CGMCC1554 AAX87003.1 Q0IJR6   8
 β-mannanase (G) 3.2.1.78 Bacillus circulans K-1 BAA25878.1 O66185   8
 BC8716_04830   Bacillus clausii DSM 8716 AST98531.1     8
 DB29_01746   Bacillus clausii ENTPro ALA52574.1     8
 ABC0320   Bacillus clausii KSM-K16 BAD62862.1 Q5WL93   8
 β-mannanase (MANPN11) (fragment) 3.2.1.78 Bacillus nealsonii PN-11 AGU71466.2
AGU71466.1
AGU71466.3
    8
 Sequence 16 from patent US 6566114   Bacillus sp. AAQ31841.1     8
 β-mannanase   Bacillus sp. AAQ31834.1     8
 Sequence 22 from patent US 6566114   Bacillus sp. AAQ31844.1     8
 Sequence 12 from patent US 6566114   Bacillus sp. AAI12 AAQ31839.1     8
 Sequence 20 from patent US 7183093 (fragment)   Bacillus sp. AAI12 ABP12275.1     8
 β-mannanase (Amn5) (Man5A) 3.2.1.78 Bacillus sp. JAMB-602 BAD99527.1 Q4W8M3 1WKY[A] 8
 β-mannanase (ManA;MAN330) (Man5A) 3.2.1.78 Bacillus sp. N16-5 AAT06599.1
AML27065.1
Q5YEX6 3JUG[A] 8
 BAA6_1442   Bifidobacterium animalis A6 AJD34555.1     8
 BGL50_07200   Bifidobacterium animalis BL3 ASL78238.1     8
 EN10_07335   Bifidobacterium animalis RH AIA33432.1     8
 BLA_0648   Bifidobacterium animalis subsp. lactis AD011 ACL28941.1 B8DWU0   8
 BLAC_07295   Bifidobacterium animalis subsp. lactis ATCC 27673 AGW85630.1     8
 W7Y_1448   Bifidobacterium animalis subsp. lactis B420 AFJ17159.1     8
 BIF_00941   Bifidobacterium animalis subsp. lactis BB-12 ADC84837.1 D3R6V5   8
 GU89_07345   Bifidobacterium animalis subsp. lactis BF052 AJD89158.1     8
 W91_1479   Bifidobacterium animalis subsp. lactis Bi-07 AFJ18748.1     8
 ManN   Bifidobacterium animalis subsp. lactis BI07 BAH23806.1 B9X294   8
 Balac_1450 3.2.1.78 Bifidobacterium animalis subsp. lactis Bl-04 ACS46797.1 C6A9J9   8
 Bl12_1362   Bifidobacterium animalis subsp. lactis Bl12 AGO52880.1     8
 BLC1_1405   Bifidobacterium animalis subsp. lactis BLC1 AEN77175.1     8
 BALAC2494_01288   Bifidobacterium animalis subsp. lactis CNCM I-2494 AEK30917.1     8
 Balat_1450   Bifidobacterium animalis subsp. lactis DSM 10140 ACS48364.1 C6AFP1   8
 U723_07350   Bifidobacterium animalis subsp. lactis KLDS2.0603 AJC77114.1     8
 BalV_1405   Bifidobacterium animalis subsp. lactis V9 ADG33993.1 D5TIR7   8
 β-1,4-mannanase (ManA) 3.2.1.78 Caldibacillus cellulovorans AAF22274.1 Q9RFX5   8
 bifunctional mannanase / endoglucanase (CbMan5A/Cel44A;Athe_1859;Cbes_1859;ORF1946) (Man5A-Cel44A) 3.2.1.4
3.2.1.78
Caldicellulosiruptor bescii DSM 6725 ACM60947.1 B9MKT9   8
 bifunctional cellulase / β-mannanase (CelC-ManB;CbCel9B/Man5A;Athe_1865;Cbes_1865;Orf1952) (Cel9B-Man5A) 3.2.1.4
3.2.1.78
Caldicellulosiruptor bescii DSM 6725 ACM60953.1 B9MKU5   8
 Athe_1866 (CelB;CbMan5C/Cel5A) (Man5C-Cel5A) 3.2.1.4 Caldicellulosiruptor bescii DSM 6725 ACM60954.1 B9MKU6   8
 Calkro_0851   Caldicellulosiruptor kronotskyensis 2002 ADQ45728.1 E4SDB9   8
 Calkro_0854   Caldicellulosiruptor kronotskyensis 2002 ADQ45730.1 E4SDC1   8
 Calkro_0856 (fragment)   Caldicellulosiruptor kronotskyensis 2002 ADQ45732.1 E4SDC3   8
 COB47_1669   Caldicellulosiruptor obsidiansis OB47 ADL42950.1 D9TFI0   8
 bifunctional β-mannanase / endo-β-1,4-glucanase (ManA) 3.2.1.4
3.2.1.78
Caldicellulosiruptor saccharolyticus AAA71887.1
AAA72861.1
P22533   8
 Csac_1077 (ManA)   Caldicellulosiruptor saccharolyticus DSM 8903 ABP66691.1 A4XIF6   8
 Csac_1080 (ManB) (fragment)   Caldicellulosiruptor saccharolyticus DSM 8903 ABP66694.1 A4XIF9   8
 CA608_04095   Caulobacter vibrioides CB2 ATC23771.1     8
 Cfla_2811   Cellulomonas flavigena DSM 20109 ADG75696.1 D5UJQ8   8
 Celgi_2637   Cellulomonas gilvus ATCC 13127 AEI13136.1     8
 CBP52_10310   Cellulomonas sp. PSBB021 ASR55418.1     8
 CBR64_11685   Cellulosimicrobium cellulans PSBB019 ARU52036.1     8
 CBR64_01715   Cellulosimicrobium cellulans PSBB019 ARU50408.1     8
 CBR64_01710   Cellulosimicrobium cellulans PSBB019 ARU50407.1     8
 endo-β-1,4-mannanase (ManB)   Cellulosimicrobium cellulans YB-43 AQQ16388.1     8
 β-1,4-mannanase (ManH) 3.2.1.78 Cellulosimicrobium sp. HY-13 AEE43708.1     8
 endo-β-1,4-mannanase 5A (CjMan5A;CJA_3338) (Man5A) 3.2.1.78 Cellvibrio japonicus Ueda107 ACE84673.1
AAO31759.1
B3PF24
Q840C2
  8
 endo-β-1,4-mannanase 5B (CJA_2475) (Man5B) 3.2.1.78 Cellvibrio japonicus Ueda107 AAO31760.1
ACE84941.1
B3PKK7
Q840C1
  8
 CBR65_07645   Cellvibrio sp. PSBB006 ARU29988.1     8
 CM240_1811   Clostridium bornimense M2/40 CDM68969.1     8
 NPD4_1214   Clostridium butyricum CDC_51208 APF25044.1     8
 ATD26_04905   Clostridium butyricum JKY6D1 ALS16221.1     8
 ATN24_06355   Clostridium butyricum KNU-L09 ALP89769.1     8
 BBB49_04985   Clostridium butyricum TK520 AOR93452.1     8
 AZ909_04800   Clostridium butyricum TOA ANF13383.1     8
 CSACC_27090 (Mana_2)   Clostridium saccharobutylicum BAS/B3/SW/136 AQS00885.1     8
 CLSA_c27120   Clostridium saccharobutylicum DSM 13864 AGX43683.1     8
 CLOSACC_27090 (Mana_2)   Clostridium saccharobutylicum NCP 195 AQS14868.1     8
 CLOSC_27020 (Mana_2)   Clostridium saccharobutylicum NCP 200 AQR90981.1     8
 CLOBY_27680 (Mana_2)   Clostridium saccharobutylicum NCP 258 AQS10623.1     8
 CYFUS_003189   Cystobacter fuscus DSM 52655 ATB37764.1     8
 EUS_11000   [Eubacterium] siraeum 70/3 CBK96294.1 D4JT75   8
 ES1_20220   [Eubacterium] siraeum V10Sc8a CBL34898.1 D4MMB5   8
 MY04_5412   Flammeovirga sp. MY04 ANQ52744.1     8
 β-mannanase   Flammeovirga yaeyamensis MY04 / CGMCC2777 ACY02072.1 D0PR29   8
 YC6258_04979 (fragment)   Gynuella sunshinyii YC6258 AJQ97011.1     8
 YC6258_03986   Gynuella sunshinyii YC6258 AJQ96022.1     8
 HCH_00087   Hahella chejuensis KCTC 2396 ABC27008.1 Q2SQR6   8
 I598_1980 (Mana_1)   Isoptericola dokdonensis DS-3 ANC31527.1     8
 Jden_2229   Jonesia denitrificans DSM 20603 ACV09866.1 C7R1N1   8
 Jden_2228   Jonesia denitrificans DSM 20603 ACV09865.1 C7R1N0   8
 CEP80_07175   Jonesia denitrificans FDAARGOS_301 ASE08942.1     8
 CEP80_07170   Jonesia denitrificans FDAARGOS_301 ASE08941.1     8
 BBK82_37940   Lentzea guizhouensis DHS C013 ANZ43360.1     8
 BBK82_42255   Lentzea guizhouensis DHS C013 ANZ41596.1     8
 BBK82_33585   Lentzea guizhouensis DHS C013 ANZ40233.1     8
 Mahau_1112   Mahella australiensis 50-1 BON AEE96309.1     8
 A3224_13320   Microbulbifer thermotolerans DAU221 AMX03424.1     8
 Micau_1708   Micromonospora aurantiaca ATCC 27029 ADL45263.1 D9SZY1   8
 GA0070611_0099   Micromonospora auratinigra DSM 44815 SBT37134.1     8
 GA0070612_5795   Micromonospora chokoriensis DSM 45160 SCF27982.1     8
 GA0070607_0868   Micromonospora coriariae DSM 44875 SCE72877.1     8
 GA0070614_4950   Micromonospora coxensis DSM 45161 SCG72161.1     8
 GA0070609_4089   Micromonospora echinaurantiaca DSM 43904 SCG65882.1     8
 GA0070610_3872   Micromonospora echinofusca DSM 43913 SCG17558.1     8
 GA0070618_0252   Micromonospora echinospora DSM 43816 SCE69983.1     8
 GA0070618_4986   Micromonospora echinospora DSM 43816 SCF29942.1     8
 GA0070621_0505   Micromonospora narathiwatensis DSM 45248 SBT38821.1     8
 GA0070621_1600   Micromonospora narathiwatensis DSM 45248 SBT42754.1     8
 GA0074696_4903   Micromonospora purpureochromogenes DSM 43821 SCF36577.1     8
 GA0070623_1979   Micromonospora rifamycinica DSM 44983 SCG51897.1     8
 GA0074704_2434   Micromonospora siamensis DSM 45097 SCG50027.1     8
 ML5_1968   Micromonospora sp. L5 ADU07496.1 D3CFW4   8
 GA0070619_0948   Micromonospora zamorensis DSM 45600 SCG40320.1     8
 Mycsm_06519   Mycobacterium sp. JS623 AGB26659.1     8
 Mycsm_06521   Mycobacterium sp. JS623 AGB26661.1     8
 B005_5164 (fragment)   Nocardiopsis alba ATCC BAA-2165 AFR10886.1     8
 CGQ36_15825   Nocardiopsis dassonvillei HZNU_N_1 ASU58942.1     8
 A9R04_15630   Nocardiopsis dassonvillei NOCA502F APC36031.1     8
 BN4615_P10778   Nonomuraea gerenzanensis ATCC 39727 SBP01262.1     8
 BKM31_49460   Nonomuraea sp. ATCC 55076 AQZ68439.1     8
 AR543_12180   Paenibacillus bovis BD3526 ANF96694.1     8
 PGRAT_09255   Paenibacillus graminis DSM 15220 AIQ67798.1     8
 BBD41_27510   Paenibacillus ihbetae IHBB 9852 ANY76761.1     8
 B4V02_01115   Paenibacillus kribbensis AM49 ASR45403.1     8
 PM3016_3709   Paenibacillus mucilaginosus 3016 AFC30528.1     8
 B2K_19295   Paenibacillus mucilaginosus K02 AFH62834.1     8
 KNP414_04275   Paenibacillus mucilaginosus KNP414 AEI42807.1     8
 PODO_19980   Paenibacillus odorifer DSM 15391 AIQ75360.1     8
 ABE82_20505   Paenibacillus peoriae HS311 ALA44923.1     8
 ABE82_03090   Paenibacillus peoriae HS311 ALA40572.1     8
 VK72_21225   Paenibacillus polymyxa ATCC 15970 APQ62216.1     8
 VK72_03240   Paenibacillus polymyxa ATCC 15970 APQ57839.1     8
 LK13_00505   Paenibacillus polymyxa CF05 AIY07141.1     8
 LK13_16140   Paenibacillus polymyxa CF05 AIY09978.1     8
 X809_02830   Paenibacillus polymyxa CR1 AHC18250.1     8
 X809_21705   Paenibacillus polymyxa CR1 AHC21581.1     8
 PPE_00597   Paenibacillus polymyxa E681 ADM68451.1 E0RFB6   8
 AOU00_15710   Paenibacillus polymyxa J AOK91139.1     8
 PPM_2466 (CelN)   Paenibacillus polymyxa M1 CCC85403.1     8
 PPM_0613 (Mana3)   Paenibacillus polymyxa M1 CCC83550.1     8
 RE92_08635   Paenibacillus polymyxa Sb3-1 AJE51127.1     8
 RE92_23915   Paenibacillus polymyxa Sb3-1 AJE53897.1     8
 PPSC2_c2748   Paenibacillus polymyxa SC2 ADO56715.1 E3E630   8
 PPSC2_c0660   Paenibacillus polymyxa SC2 ADO54643.1 E3EGK4   8
 PPSQR21_006420   Paenibacillus polymyxa SQR-21 SQR21 AHM64305.1     8
 PPSQR21_025410   Paenibacillus polymyxa SQR-21 SQR21 AHM66183.1     8
 PPYC1_21305   Paenibacillus polymyxa YC0136 APB72758.1     8
 PPYC2_23520   Paenibacillus polymyxa YC0573 APB77737.1     8
 PRIO_1944   Paenibacillus riograndensis SBR5 CQR54354.1     8
 β-mannanase   Paenibacillus sp. A1 ACU30843.1 C7FFF2   8
 β-1,4-mannanase (ManB)   Paenibacillus sp. CH-3 AEX60762.1     8
 H70357_25710   Paenibacillus sp. FSL H7-0357 AIQ19732.1     8
 P40081_26410   Paenibacillus sp. FSL P4-0081 AIQ31305.1     8
 ASL14_08775 (fragment)   Paenibacillus sp. IHB B 3084 ALP36244.1     8
 endoglucanase (EG5A)   Paenibacillus sp. IHB B 3084 AHA61670.1
ALP37050.1
    8
 CIC07_01570   Paenibacillus sp. RUD330 ASS64945.1     8
 PSTEL_01805   Paenibacillus stellifer DSM 14472 AIQ62043.1     8
 HPL003_05715   Paenibacillus terrae HPL-003 AET57908.1     8
 BS614_17280   Paenibacillus xylanexedens PAMC 22703 APO45595.1     8
 CIK06_09835   Plantactinospora sp. KBS50 ASW54425.1     8
 β-1,4-mannanase (AmnA)   Pseudomonas sp. ND137 BAB79290.2 Q8RR71   8
 Rumal_1363   Ruminococcus albus 7 = DSM 20455 ADU21877.1 E0L9P6   8
 Rumal_2599   Ruminococcus albus 7 = DSM 20455 ADU23074.1 E0L8X6   8
 RBI_I00637 (ManA)   Ruminococcus bicirculans 80/3 CCO04360.1     8
 β-mannanase (GH5C;RUM_21650) (Man5A) 3.2.1.78 Ruminococcus champanellensis 18P13 = JCM 17042 CBL18180.1 D4LEY5   8
 RfGH5-1/2   Ruminococcus flavefaciens WP_009984467.1     8
 Sde_0064 (Man5N)   Saccharophagus degradans 2-40 ABD79328.1 Q21PQ1   8
 Sde_0656 (Man5O)   Saccharophagus degradans 2-40 ABD79918.1 Q21N11   8
 β-mannanase (Man5A) 3.2.1.78 Salipaludibacillus agaradhaerens AAN27517.1
AAN27518.1
AAQ31837.1
AAQ79152.1
AAQ79153.1
ABC13790.1
ABC13791.1
  2WHJ[A]
2WHL[A]
8
 STHERM_c12480   Spirochaeta thermophila DSM 6192 ADN02189.1 E0RTF8   8
 Spith_1286   Spirochaeta thermophila DSM 6578 AEJ61551.1     8
 SGGB_0206 (GmuG)   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143 BAK27103.1     8
 SGGBAA2069_c01800   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069 CBZ47352.1     8
 BTR42_00825   Streptococcus gallolyticus subsp. gallolyticus DSM 16831 AQP41170.1     8
 GALLO_0162   Streptococcus gallolyticus UCN34 CBI12654.1 D3HC62   8
 AU079_01000 (fragment)   Streptococcus infantarius ICDDRB-NRC-S5 ALT81993.1     8
 SAM23877_4871 (ManA)   Streptomyces ambofaciens ATCC 23877 AKZ57916.1     8
 SAM23877_6969   Streptomyces ambofaciens ATCC 23877 AKZ60014.1     8
 SAMR0614   Streptomyces ambofaciens ATCC 23877 CAJ88324.1 A0ACW9   8
 SAM40697_4389   Streptomyces ambofaciens DSM 40697 ANB08347.1     8
 SAM40697_6286   Streptomyces ambofaciens DSM 40697 ANB10239.1     8
 BV401_06615   Streptomyces autolyticus CGMCC0516 AQA16021.1     8
 SBI_09150   Streptomyces bingchenggensis BCW-1 ADI12268.1 D7C3Q2   8
 SCO6234 (ManA2;SC2H4.16)   Streptomyces coelicolor A3(2) CAA20610.1
NP_630335.1
O86599   8
 SCO0554 (ManA;SCF11.34c)   Streptomyces coelicolor A3(2) CAD55266.1
CAB57406.1
CAB59611.1
NP_733506.1
Q8CK53   8
 TU94_04450   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP00836.1     8
 BN159_5046   Streptomyces davawensis JCM 4913 CCK29425.1     8
 β-1,4-mannase   Streptomyces fradiae k11 ADK91084.1     8
 SGLAU_25530   Streptomyces glaucescens GLA.O AIS01044.1     8
 SGLAU_28405   Streptomyces glaucescens GLA.O AIS01618.1     8
 SHXM_01100   Streptomyces hygroscopicus XM201 AQW47637.1     8
 SIRAN8881   Streptomyces iranensis CDR16057.1     8
 Sle_14000   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR60862.1     8
 Sle_59560   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR65412.1     8
 SLINC_1228   Streptomyces lincolnensis NRRL 2936 ANS63452.1     8
 β-mannanase (ManA;SlMan) 3.2.1.78 Streptomyces lividans 1326 AAA26710.2 P51529   8
 SLIV_35170   Streptomyces lividans TK24 AIJ17911.1     8
 SLIV_06970 (CelA)   Streptomyces lividans TK24 AIJ12409.1     8
 SMALA_0561   Streptomyces malaysiensis DSM 4137 ATL80796.1     8
 B1H29_02170   Streptomyces pactum ACT12 AQS65900.1     8
 Sfla_4025   Streptomyces pratensis ATCC 33331 ADW05439.1 C9NFU2   8
 SPRI_0552   Streptomyces pristinaespiralis HCCB 10218 ALC18858.1     8
 SPRI_0824   Streptomyces pristinaespiralis HCCB 10218 ALC19130.1     8
 M271_44965   Streptomyces rapamycinicus NRRL 5491 AGP60361.1     8
 TUE45_06438 (Mana_2)   Streptomyces reticuli CUW31689.1     8
 A4G23_00338 (Mana_3)   Streptomyces rubrolavendulae MJM4426 AOT57549.1     8
 SCAB_78881   Streptomyces scabiei 87.22 CBG74852.1 C9ZCR3   8
 SCAB_82021   Streptomyces scabiei 87.22 CBG75158.1 C9YU29   8
 A7J05_02570   Streptomyces silaceus ACCC40021 APY84783.1     8
 CGL27_05725   Streptomyces sp. 11-1-2 ASQ92711.1     8
 SAMN05428941_6359   Streptomyces sp. 2114.2 SDT78278.1     8
 SAMN05428941_0608   Streptomyces sp. 2114.2 SDS50526.1     8
 SAMN05444521_8314   Streptomyces sp. 3124.6 SHI71357.1     8
 NI25_01330   Streptomyces sp. CCM_MD2014 AIV32327.1     8
 AS200_38935   Streptomyces sp. CdTB01 ALV37404.1     8
 AA958_33630   Streptomyces sp. CNQ-509 AKH86353.1     8
 F750_2698   Streptomyces sp. PAMC 26508 AGJ55179.1     8
 QR97_21190   Streptomyces sp. PBH53 AKN71965.1     8
 A4E84_04775   Streptomyces sp. S10(2016) AMW08869.1     8
 β-1,4-mannanase (Man5S27) 3.2.1.78 Streptomyces sp. S27 ADK91085.1 E2F4D4   8
 β-1,4-mannanase   Streptomyces sp. s6-204 ABY90130.1 B0ZSE6   8
 CAG99_02395   Streptomyces sp. SCSIO 03032 ARQ67834.1     8
 β-mannanase (SACTE_2347) 3.2.1.78 Streptomyces sp. SirexAA-E AEN10237.1   4FK9[A] 8
 β-mannanase (Man;StMan) 3.2.1.78 Streptomyces thermolilacinus NBRC14274 BAK26781.1   3WSU[A,B]
4Y7E[A,B]
8
 β-mannanase (ManII;StManII) 3.2.1.78 Streptomyces thermoluteus NBRC 14269 BAM62868.1     8
 SVEN_6894   Streptomyces venezuelae ATCC 10712 CCA60180.1     8
 SVEN_6905   Streptomyces venezuelae ATCC 10712 CCA60191.1     8
 Strvi_5490   Streptomyces violaceusniger Tu 4113 AEM85012.1     8
 SXIM_49310   Streptomyces xiamenensis 318 AKG46315.1     8
 Sros_0934   Streptosporangium roseum DSM 43021 ACZ83938.1 D2B807   8
 TERTU_4344   Teredinibacter turnerae T7901 ACR11348.1 C5BIG0   8
 TERTU_2894   Teredinibacter turnerae T7901 ACR13797.1 C5BNA8   8
 mannan endo-1,4-beta mannosidase   Thermobifida alba AHK119 BBA57841.1     8
 endomannanase (Man5A) 3.2.1.78 Thermobifida cellulosilytica TB100 AHB89703.1     8
 exo-β-D-mannanase   Thermobifida fusca BCRC1914 AID15578.1     8
 endomannanase, partial (fragment)   Thermobifida fusca CECT 3323 AKJ70979.1     8
 β-mannanase (Man) (partial) 3.2.1.78 Thermobifida fusca KW3 CAA06924.1 Q9ZF13 2MAN[A]
3MAN[A]
1BQC[A]
8
 endomannanase (TM51_04883) (Man5A) 3.2.1.78 Thermobifida fusca TM51 AHB89702.1     8
 β-mannanase (Man;TfMan;Tfu-man;Tfu_0900) 3.2.1.78 Thermobifida fusca YX AAZ54938.1 Q47RH9   8
 endomannanase (Man5A)   Thermobifida halotolerans YIM90462 AHB89704.1     8
 Tbis_0925   Thermobispora bispora DSM 43833 ADG87649.1 D6Y754   8
 VAB18032_13185   Verrucosispora maris AB-18-032 AEB43751.1     8
 AL536_06080   Vibrio fluvialis ATCC 33809 AMF93023.1     8
 vfu_B00526   Vibrio furnissii NCTC 11218 ADT88758.1     8
 BSQ33_10390   Vibrio gazogenes ATCC 43942 ASA57159.1     8
 β-mannanase (ManA) 3.2.1.78 Vibrio sp. MA-138 BAA25188.1 O69347   8
 AKJ12_09710   Xanthomonas arboricola pv. juglandis Xaj 417 AKU50026.1     8
 XAC1796   Xanthomonas axonopodis pv. citri str. 306 AAM36659.1
NP_642123.1
Q8PLK1   8
 XACM_1819   Xanthomonas axonopodis pv. citrumelo F1 AEO42095.1     8
 XAC29_09020   Xanthomonas axonopodis Xac29-1 AGH77288.1     8
 XB05_04035   Xanthomonas campestris 17 AKC78007.1     8
 AAW18_08870   Xanthomonas campestris pv. campestris 17 ALE68568.1     8
 AEA01_11715   Xanthomonas campestris pv. campestris 4013 AKS20523.1     8
 AEA00_11550   Xanthomonas campestris pv. campestris ICMP 21080 AKS16497.1     8
 endo-β-1,4-mannanase (ManA;XC_2458)   Xanthomonas campestris pv. campestris str. 8004 AAY49508.1 Q4UTW5   8
 endo-β-1,4-mannosidase (ManA;XCC1778) 3.2.1.78 Xanthomonas campestris pv. campestris str. ATCC 33913 AAM41068.1
NP_637144.1
Q8P9S0   8
 xcc-b100_2486 (ManA)   Xanthomonas campestris pv. campestris str. B100 CAP51846.1 Q8P9S0   8
 XCR_2021   Xanthomonas campestris pv. raphani 756C AEL06909.1     8
 XCV1826   Xanthomonas campestris pv. vesicatoria str. 85-10 AOY65436.1
CAJ23503.1
Q3BUK6   8
 AB890_09100   Xanthomonas citri pv. citri jx-6 AKM24907.1     8
 BJD09_07000   Xanthomonas citri pv. citri LH201 APR24002.1     8
 BI316_10975   Xanthomonas citri pv. citri LH276 APR19979.1     8
 BI315_22910   Xanthomonas citri pv. citri LJ207-7 APR17238.1     8
 BI314_15315   Xanthomonas citri pv. citri LL074-4 APR11329.1     8
 A9D66_09630   Xanthomonas citri pv. glycines str. 12-2 ARV22849.1     8
 BHE84_14980   Xanthomonas citri pv. glycines str. 8ra AOY63331.1     8
 BGK55_12365   Xanthomonas citri pv. malvacearum MSCT AOL21669.1     8
 XcvCFBP7111P_14665   Xanthomonas citri pv. vignicola CFBP7111 ASK92568.1     8
 XcvCFBP7113P_13085   Xanthomonas citri pv. vignicola CFBP7113 ASL01161.1     8
 J152_01948   Xanthomonas citri subsp. citri 5208 AJZ39612.1     8
 J151_01952   Xanthomonas citri subsp. citri A306 AJD68390.1     8
 XCAW_02609   Xanthomonas citri subsp. citri Aw12879 AGI08391.1     8
 J165_02617   Xanthomonas citri subsp. citri AW13 AJZ44727.1     8
 J166_02619   Xanthomonas citri subsp. citri AW14 AJZ49344.1     8
 J167_02618   Xanthomonas citri subsp. citri AW15 AJZ53963.1     8
 J168_02618   Xanthomonas citri subsp. citri AW16 AJZ66758.1     8
 J170_01943   Xanthomonas citri subsp. citri BL18 AJZ35142.1     8
 J171_01945   Xanthomonas citri subsp. citri FB19 AJZ30679.1     8
 J154_01942   Xanthomonas citri subsp. citri gd2 AJZ26252.1     8
 J155_01942   Xanthomonas citri subsp. citri gd3 AJZ21826.1     8
 J156_01942   Xanthomonas citri subsp. citri jx4 AJZ17402.1     8
 J157_01942   Xanthomonas citri subsp. citri jx5 AJZ12973.1     8
 J172_01943   Xanthomonas citri subsp. citri mf20 AJZ08511.1     8
 J162_01940   Xanthomonas citri subsp. citri MN10 AJZ04080.1     8
 J163_01940   Xanthomonas citri subsp. citri MN11 AJY99656.1     8
 J164_01940   Xanthomonas citri subsp. citri MN12 AJY95232.1     8
 J169_01949   Xanthomonas citri subsp. citri NT17 AJY90770.1     8
 B7L65_14570   Xanthomonas citri subsp. citri TX160042 ARR17990.1     8
 B7L66_12885   Xanthomonas citri subsp. citri TX160149 ARR13012.1     8
 B7L67_22060   Xanthomonas citri subsp. citri TX160197 ARR23898.1     8
 J158_01940   Xanthomonas citri subsp. citri UI6 AJY86337.1     8
 CIW71_14050   Xanthomonas citri subsp. malvacearum AR81009 ASY84934.1     8
 CIW72_13035   Xanthomonas citri subsp. malvacearum MS14003 ASY89146.1     8
 APY29_13015   Xanthomonas citri subsp. malvacearum XcmH1005 ASN01697.1     8
 APY30_08965   Xanthomonas citri subsp. malvacearum XcmN1003 ASN09173.1     8
 BJD11_13375   Xanthomonas euvesicatoria LMG930 APO90896.1     8
 AC028_16915   Xanthomonas fuscans subsp. aurantifolii 1566 AMV08302.1     8
 TP37_09655   Xanthomonas fuscans subsp. aurantifolii FDC 1559 AMU98328.1     8
 TP50_13060   Xanthomonas fuscans subsp. aurantifolii FDC 1609 AMV03262.1     8
 CKU38_01961   Xanthomonas fuscans subsp. fuscans FX01 ATB58413.1     8
 XFF4834R_chr19250   Xanthomonas fuscans subsp. fuscans str. 4834-R CDF61485.1     8
 BI317_14090   Xanthomonas gardneri ICMP 7383 APP85122.1     8
 BJD10_16065   Xanthomonas gardneri JS749-3 APP81017.1     8
 XJ27_02385   Xanthomonas hortorum B07-007 ASW44949.1     8
 AXO1947_11665   Xanthomonas oryzae pv. oryzae AXO1947 ALS95081.1     8
 ACU13_11350   Xanthomonas oryzae pv. oryzicola B8-12 AKN93543.1     8
 XOC_2180   Xanthomonas oryzae pv. oryzicola BLS256 AEQ96320.1     8
 ACU10_11295   Xanthomonas oryzae pv. oryzicola BLS279 AKN97274.1     8
 ACU15_11085   Xanthomonas oryzae pv. oryzicola BXOR1 AKO00963.1     8
 ACU11_09770   Xanthomonas oryzae pv. oryzicola CFBP2286 AKO19701.1     8
 ACU16_12055   Xanthomonas oryzae pv. oryzicola CFBP7331 AKO04761.1     8
 ACU17_11865   Xanthomonas oryzae pv. oryzicola CFBP7341 AKO08642.1     8
 BE73_10360   Xanthomonas oryzae pv. oryzicola CFBP7342 AJQ87442.1     8
 ACU14_11295   Xanthomonas oryzae pv. oryzicola L8 AKO12488.1     8
 ACU12_11335   Xanthomonas oryzae pv. oryzicola RS105 AKO16234.1     8
 FE36_08755   Xanthomonas oryzae pv. oryzicola YM15 AKK63920.1     8
 XPE_03335   Xanthomonas perforans 91-118 AQS75467.1     8
 BJD13_07590   Xanthomonas perforans LH3 APO98954.1     8
 BJD12_00055   Xanthomonas vesicatoria ATCC 35937 LMG 911 APP73913.1     8
 Xcel_0504   Xylanimonas cellulosilytica DSM 15894 ACZ29543.1 D1BW40   8
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 β-mannanase (Man1;HhMAN1) 3.2.1.78 Hypothenemus hampei ACU52526.1
ACU52527.1
C8CAP6   8
unclassified
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 SARM_0038 / 798985_48230 / TW-11   uncultured organism ADX05709.1     8
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