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Glycoside Hydrolase Family 5 / Subf 7

Activities in Sub Familyβ-mannosidase (EC 3.2.1.25);
Endo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (1545); Uniprot accession (72); PDB accession (28); 3D entries (10); cryst (0)
Summary
Download GH5_7 (2992) Taxonomic display Structure (10) Characterized (65)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 23 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 β-mannanase (Man5P1;NFIA_113780) 3.2.1.78 Aspergillus fischeri NRRL 181 NRRL 181 / P1 XP_001262744.1 A1D8Y6   7
 G4B11_009786   Aspergillus flavus AF13 QMW46331.1     7
 G4B11_012225   Aspergillus flavus AF13 QMW48707.1     7
 AFCA_010467   Aspergillus flavus CA14 UDD63194.1     7
 AFCA_013128   Aspergillus flavus CA14 UDD65966.1     7
 F9C07_8411   Aspergillus flavus NRRL 3357 QRD93959.1     7
 F9C07_12267   Aspergillus flavus NRRL 3357 QRD92290.1     7
 G4B84_012180   Aspergillus flavus NRRL3357 QMW36651.1     7
 G4B84_009744   Aspergillus flavus NRRL3357 QMW34278.1     7
 31921   Aspergillus flavus NRRL3357 (Aspfl1)       7
 26030   Aspergillus flavus NRRL3357 (Aspfl1)       7
 8411   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)       7
 12267   Aspergillus flavus NRRL3357 v1.0 (Aspfl2_3)       7
 endo-β-1,4-mannosidase (ManAF)   Aspergillus flavus UKM-1 ADZ75457.1     7
 107014   Aspergillus fumigatus A1163 (Aspfu_A1163_1)       7
 107666   Aspergillus fumigatus A1163 (Aspfu_A1163_1)       7
 endo-β-1,4-mannanase (Man I;Man II;AFUA_8G07030;Afu8g07030) 3.2.1.78 Aspergillus fumigatus Af293 EAL85463.1 Q4WBS1   7
 9741   Aspergillus fumigatus Af293 (Aspfu1)       7
 8613   Aspergillus fumigatus Af293 (Aspfu1)       7
 endo-β-1,4-mannanase (ManF;Man I;Man II) (partial) 3.2.1.78 Aspergillus fumigatus IMI 385708 ACH58410.1
ACH58411.1		 B5LZ77
B5LZ78
Q4WBS1		   7
 18712   Aspergillus kawachii IFO 4308 (Aspka1_1)       7
 198947   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)       7
 162651   Aspergillus leporis CBS 151.66 v1.0 (Asplep1)       7
 380894   Aspergillus acidus v1 (Aspfo1)       7
 AKAW2_81270A   Aspergillus luchuensis IFO 4308 BCS05469.1     7
 endo-β-1,4-mannanase (ManAK; AKAW_07239 3.2.1.78 Aspergillus luchuensis IFO 4308 GAA89125.1     7
 ALUC_81230A   Aspergillus luchuensis RIB2601 BCS17023.1     7
 226292   Aspergillus minisclerotigenes v1.0 (Aspmin1)       7
 234146   Aspergillus minisclerotigenes v1.0 (Aspmin1)       7
 5119   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 9468   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 3486   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 8741   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 3799   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 8805   Aspergillus nidulans FGSC A4 (Aspnid1)       7
 AN2709.2 (frameshift)   Aspergillus nidulans FGSC A4 EAA63111.1     7
 AN7639.2   Aspergillus nidulans FGSC A4 EAA61825.1     7
 AN9276.2   Aspergillus nidulans FGSC A4 EAA66343.1     7
 endo-β-1,4-mannanase (ManA;AnMan5A;AN3358) (Man5A) 3.2.1.78 Aspergillus nidulans FGSC A4 ABF50863.1
EAA63326.1		 Q5B7X2   7
 endo-β-1,4-mannanase (ManB;AnMan5B;AN3297) (Man5B) 3.2.1.78 Aspergillus nidulans FGSC A4 ABF50861.1
EAA63265.1		 Q5B833   7
 endo-β-1,4-mannanase (ManC;AnMan5C;AN6427;ANID_06427) (Man5C) 3.2.1.78 Aspergillus nidulans FGSC A4 EAA58449.1
ABF50878.1		 Q5AZ53   7
 β-mannanase (Man5;Man5XZ3) 3.2.1.78 Aspergillus nidulans XZ3 AGG69666.1 S4TZC3   7
 β-mannanase, partial   Aspergillus niger AKC57288.1     7
 215623   Aspergillus phoenicis (Corda) Thom ATCC 13157 v1.0 (Aspph1)       7
 endo-β-1,4-mannanase   Aspergillus niger 128 ADK88903.1     7
 1142884   Aspergillus niger ATCC 1015 v4 (Aspni7)       7
 β-mannanase   Aspergillus niger BCC4525 AJZ68815.1     7
 β-mannanase   Aspergillus niger BCC4525 AJZ68815.2     7
 endo-β-1,4-mannanase (ManBK) (partial) 3.2.1.78 Aspergillus niger BK 01 ACJ06979.1 B6V876 3WH9[A,B] 7
 β-mannanase (An05g01320) (Man5A) 3.2.1.78 Aspergillus niger CBS 513.88 CAK96471.1 A2QKT4   7
 159852   Aspergillus niger CBS 513.88 (Aspni_DSM_1)       7
 β-mannanase   Aspergillus niger GIM3.452 AKC98250.1     7
 endo-β-1,4-mannanase (AnMan5A) (acidic) (Man5A) 3.2.1.78 Aspergillus niger LW-1 / E-30 AEY76082.1
AEP84473.1		 G5CJA5
H2E6Y8		   7
 8912   Aspergillus niger NRRL3 (Aspni_NRRL3_1)       7
 244861   Aspergillus niger van Tieghem ATCC 13496 v1.0 (Aspni_bvT_1)       7
 156896   Aspergillus nomius v1.0 (Aspnom1)       7
 136558   Aspergillus nomius v1.0 (Aspnom1)       7
 142797   Aspergillus nomius v1.0 (Aspnom1)       7
 5458   Aspergillus nomius NRRL 13137 (Aspnom13137_1)       7
 5874   Aspergillus nomius NRRL 13137 (Aspnom13137_1)       7
 515520   Aspergillus novofumigatus IBT 16806 v1 (Aspnov1)       7
 229589   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)       7
 3981   Aspergillus novoparasiticus CBS 126849 v1.0 (Aspnovo1)       7
 492671   Aspergillus ochraceoroseus IBT 24754 v1.0 (Aspoch1)       7
 AO090038000444 (ManD)   Aspergillus oryzae RIB40 BAE64232.1     7
 AO090010000122 (ManG)   Aspergillus oryzae RIB40 BAE66031.1     7
 11911   Aspergillus oryzae RIB40 (Aspor1)       7
 9461   Aspergillus oryzae RIB40 (Aspor1)       7
 186738   Aspergillus parasiticus CBS 117618 v1.0 (Asppar1)       7
 234132   Aspergillus parasiticus CBS 117618 v1.0 (Asppar1)       7
 132601   Aspergillus parvisclerotigenus CBS 121.62 v1.0 (Asppari1)       7
 383333   Aspergillus parvisclerotigenus CBS 121.62 v1.0 (Asppari1)       7
 213282   Aspergillus pseudocaelatus CBS 117616 v1.0 (Asppsec1)       7
 301358   Aspergillus pseudocaelatus CBS 117616 v1.0 (Asppsec1)       7
 272572   Aspergillus pseudonomius CBS 119388 v1.0 (Asppsen1)       7
 68155   Aspergillus pseudonomius CBS 119388 v1.0 (Asppsen1)       7
 269762   Aspergillus pseudonomius CBS 119388 v1.0 (Asppsen1)       7
 279020   Aspergillus pseudotamarii CBS 117625 v1.0 (Asppset1)       7
 272817   Aspergillus pseudotamarii CBS 117625 v1.0 (Asppset1)       7
 APUU_41330S   Aspergillus puulaauensis MK2 BCS24886.1     7
 APUU_21961S   Aspergillus puulaauensis MK2 BCS21529.1     7
 APUU_31404S (Mana1)   Aspergillus puulaauensis MK2 BCS23179.1     7
 APUU_51452A   Aspergillus puulaauensis MK2 BCS26741.1     7
 216768   Aspergillus sergii CBS 130017 v1.0 (Aspser1)       7
 216940   Aspergillus sergii CBS 130017 v1.0 (Aspser1)       7
 endo-β-1,4-mannanase 3.2.1.78 Aspergillus sp. T16 AHA38074.1 A0A0B4KYG3   7
 348376   Aspergillus steynii IBT 23096 v1 (Aspste1)       7
 511963   Aspergillus steynii IBT 23096 v1 (Aspste1)       7
 β-mannanase (MANN) 3.2.1.78 Aspergillus sulphureus ABC59553.1 Q2LE69   7
 β-mannanase 3.2.1.78 Aspergillus sulphureus 138284 ABE73149.1     7
 58369   Aspergillus sydowii v1 (Aspsy1)       7
 43475   Aspergillus sydowii v1 (Aspsy1)       7
 208061   Aspergillus sydowii v1 (Aspsy1)       7
 91697   Aspergillus sydowii v1 (Aspsy1)       7
 160296   Aspergillus taichungensis IBT 19404 v1.0 (Asptaic1)       7
 182946   Aspergillus taichungensis IBT 19404 v1.0 (Asptaic1)       7
 284776   Aspergillus tamarii CBS 117626 v1.0 (Asptam1)       7
 308437   Aspergillus tamarii CBS 117626 v1.0 (Asptam1)       7
 6232   Aspergillus terreus NIH 2624 (Aspte1)       7
 2792   Aspergillus terreus NIH 2624 (Aspte1)       7
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