Glycoside Hydrolase Family 5 / Subf 7

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (504); Uniprot accession (158); PDB accession (26); 3D entries (10); cryst (0)
| 1 | 2 | 3 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 VITISV_020726 (fragment)   Vitis vinifera CAN70632.1 A5BWB8   7
 VITISV_023481 (short fragment)   Vitis vinifera CAN71993.1 A5AS93   7
 VITISV_023482 (short fragment)   Vitis vinifera CAN71994.1 A5B3T1   7
 VITISV_023484   Vitis vinifera CAN71995.1 A5B3T2   7
 VITISV_033630   Vitis vinifera CAN77937.1 A5AHI3   7
 unknown   Zea mays ACG41070.1
ACL54560.1
B6TVD7   7
 unknown (fragment)   Zea mays ACG41765.1     7
 unknown (frameshift)   Zea mays ACG42480.1     7
 unknown (fragment)   Zea mays B73 ACN33740.1
ACL52784.1
B7ZXY5
C0PEX4
  7
 unknown   Zea mays B73 ACN33727.1 C0PEW1   7
 unknown (ZM_BFb0114N09)   Zea mays B73 ACF78505.1
ACN30643.1
B4F8R2   7
 unknown (ZM_BFc0049D02)   Zea mays B73 ACF87838.1 B4F8R2   7
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