Glycoside Hydrolase Family 5 / Subf 5

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (3516); Uniprot accession (276); PDB accession (20); 3D entries (9); cryst (0)
All (3119) Bacteria (2943) Eukaryota (174) unclassified (2) Structure (9) Characterized (60)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 30 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 EgL (fragment)   Ralstonia solanacearum CIP120 ACY07778.1 D0UVE5   5
 Egl (fragment)   Ralstonia solanacearum CIP214 ABR53899.1 B6C855   5
 Egl (fragment)   Ralstonia solanacearum CIP224 ABR53896.1 B6C852   5
 Egl (fragment)   Ralstonia solanacearum CIP238 ABR53891.1
ABR53892.1
ABR53893.1
B6C847   5
 EgL (fragment)   Ralstonia solanacearum CIP240 ABR53897.1 B6C853   5
 Egl (fragment)   Ralstonia solanacearum CIP301 ADD24683.1 D3XC71   5
 EgL (fragment)   Ralstonia solanacearum CIP301 AEV52809.1     5
 Egl (fragment)   Ralstonia solanacearum CIP312 ABR53898.1 B6C854   5
 endo-1,4-β-glucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP358 AMW89513.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_10 ATB17175.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_102 ATB17176.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_116 ATB17177.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_12 ATB17179.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_120 ATB17180.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_128 ATB17181.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_129 ATB17182.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_13 ATB17183.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_137 ATB17185.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_14 ATB17186.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_142 ATB17188.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_147 ATB17189.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_15 ATB17190.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_16 ATB17191.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_161 ATB17192.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_162 ATB17193.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_17 ATB17194.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_172 ATB17195.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_173 ATB17196.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_174 ATB17197.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_177 ATB17198.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_18 ATB17200.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_183 ATB17201.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_184 ATB17202.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_185 ATB17203.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_187 ATB17204.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_190 ATB17205.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_198 ATB17206.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_199 ATB17207.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_200 ATB17208.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_201 ATB17209.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_202 ATB17210.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_203 ATB17211.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_204 ATB17212.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_206 ATB17213.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_207 ATB17214.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_208 ATB17215.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_245 ATB17217.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_246 ATB17218.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_252 ATB17219.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_253 ATB17220.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_254 ATB17221.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_255 ATB17222.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_256 ATB17223.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_262 ATB17224.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_269 ATB17227.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_270 ATB17228.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_272 ATB17229.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_275 ATB17230.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_3 ATB17231.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_300 ATB17232.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_301 ATB17233.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_302 ATB17234.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_303 ATB17235.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_304 ATB17236.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_305 ATB17237.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_306 ATB17238.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_307 ATB17239.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_308 ATB17240.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_311 ATB17241.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_312 ATB17242.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_313 ATB17243.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_314 ATB17244.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_373 ATB17245.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_383 ATB17246.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_384 ATB17247.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_385 ATB17248.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_386 ATB17249.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_387 ATB17250.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_388 ATB17251.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_4 ATB17252.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_42 ATB17253.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_426 ATB17254.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_430 ATB17255.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_431 ATB17256.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_432 ATB17257.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_433 ATB17258.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_435 ATB17259.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_437 ATB17260.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_451 ATB17261.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_452 ATB17262.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_453 ATB17263.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_454 ATB17264.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_467 ATB17265.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_468 ATB17266.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_469 ATB17267.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_470 ATB17268.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_471 ATB17269.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_473 ATB17270.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_476 ATB17271.1     5
 endoglucanase, partial (EgL) (fragment)   Ralstonia solanacearum CIP_477 ATB17272.1     5
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