Glycoside Hydrolase Family 5 / Subf 56

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (16); Uniprot accession (2);
All (17) Bacteria (17)
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 A2T82_25055   Burkholderia cenocepacia 842 AMU09523.1     56
 A3203_00800   Burkholderia cenocepacia 895 AMU11760.1     56
 BCN122_II0837   Burkholderia cenocepacia GIMC4560:Bcn122 ARF87580.1     56
 I35_4662   Burkholderia cenocepacia H111 CDN62498.1     56
 BCAM0763   Burkholderia cenocepacia J2315 CAR54623.1 B4EM65   56
 TQ36_22820   Burkholderia cenocepacia ST32 ALV59050.1     56
 A8E75_03480   Burkholderia cenocepacia VC12308 AQQ38115.1     56
 A8F32_08455   Burkholderia cenocepacia VC1254 AQQ45904.1     56
 A8D61_32370   Burkholderia cenocepacia VC2307 AQQ22760.1     56
 DM42_4324   Burkholderia cepacia DDS 7H-2 AIO45436.1     56
 P350_20290   Burkholderia cepacia JBK9 ALX13947.1     56
 P350_20290   Burkholderia cepacia JBK9 ALX13947.1     56
 Bcep18194_B2374   Burkholderia lata sp. 383 ABB12485.1 Q392Y1   56
 bAD24_III12350 (SacC)   Burkholderia sp. AD24 ASL48181.1     56
 BBJ41_31450   Burkholderia stabilis ATCC BAA-67 AOR71938.1     56
 OI25_7004   Paraburkholderia fungorum ATCC BAA-463 AJZ63719.1     56
 BJG93_26375   Paraburkholderia sprentiae WSM5005 APA89338.1     56

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