Glycoside Hydrolase Family 5 / Subf 47

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (15); Uniprot accession (6);
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 CCB80_07970   Armatimonadetes bacterium Uphvl-Ar1 ARU41080.1     47
 CJA_3305 (Glu5A)   Cellvibrio japonicus Ueda107 ACE82980.1 B3PEK3   47
 CBR65_12675   Cellvibrio sp. PSBB006 ARU30072.1     47
 CBR65_12685   Cellvibrio sp. PSBB006 ARU28213.1     47
 B0D95_12545   Cellvibrio sp. PSBB023 AQT62434.1     47
 OP10G_2899   Fimbriimonas ginsengisoli Gsoil 348 AIE86267.1     47
 Hoch_4284   Haliangium ochraceum DSM 14365 ACY16781.1 D0LM75   47
 BN2497_2063   Janthinobacterium sp. CG23_2 CUI19256.1     47
 CR152_20210   Massilia sp. B2 ATQ79009.1     47
 AAW51_0645   [Polyangium] brachysporum DSM 7029 AKJ27336.1     47
 Rfer_1104   Rhodoferax ferrireducens T118 DSM 15236 ABD68845.1 Q21ZF8   47
 Sde_2996 (Gly5L)   Saccharophagus degradans 2-40 ABD82253.1 Q21GC6   47
 β-1,3-1,6-endoglucanase (Sde_3023) (Gly5M) 3.2.1.39
3.2.1.75
Saccharophagus degradans 2-40 ABD82280.1 Q21G99   47
 M5M_06655   Simiduia agarivorans SA1 = DSM 21679 AFU98526.1     47
 TERTU_4085   Teredinibacter turnerae T7901 ACR14401.1 C5BUE0   47
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