Glycoside Hydrolase Family 5 / Subf 44

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (150); Uniprot accession (16);
All (148) Bacteria (148) Characterized (1)
| 1 | 2 |
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 C8077_07350   Bifidobacterium adolescentis 1-11 AVT45730.1     44
 BADO_1350   Bifidobacterium adolescentis 22L AII76760.1     44
 BADO_1348   Bifidobacterium adolescentis 22L AII76759.1     44
 BAD_1202   Bifidobacterium adolescentis ATCC 15703 BAF39983.1 A1A2Q0   44
 BAD_1204   Bifidobacterium adolescentis ATCC 15703 BAF39985.1 A1A2Q2   44
 BBMN23_1378   Bifidobacterium adolescentis BBMN23 AJE06350.1     44
 BBMN23_1380   Bifidobacterium adolescentis BBMN23 AJE06352.1     44
 BB017W439_1522   Bifidobacterium breve 017W439 AUD95818.1     44
 BB082W48_1492   Bifidobacterium breve 082W48 AUD97712.1     44
 B12L_1363   Bifidobacterium breve 12L AHJ16099.1     44
 BB139W423_1576   Bifidobacterium breve 139W423 AUD99682.1     44
 BB180W83_1480   Bifidobacterium breve 180W83 AUE01600.1     44
 BB215W447A_1763   Bifidobacterium breve 215W447a AUE03767.1     44
 B689b_1459   Bifidobacterium breve 689b AHJ23454.1     44
 HMPREF9228_1484   Bifidobacterium breve ACS-071-V-Sch8b AEF27080.1     44
 RY69_391   Bifidobacterium breve BR3 ALE12653.1     44
 CNCMI4321_1579   Bifidobacterium breve CNCM I-4321 AUE05786.1     44
 DRBB26_1559   Bifidobacterium breve DRBB26 AUD89679.1     44
 DRBB27_1622   Bifidobacterium breve DRBB27 AUD91727.1     44
 DRBB28_1676   Bifidobacterium breve DRBB28 AUD93855.1     44
 DRBB29_1623   Bifidobacterium breve DRBB29 AUE19159.1     44
 DRBB30_1577   Bifidobacterium breve DRBB30 AUE21209.1     44
 BBBR_1476   Bifidobacterium breve DSM 20213 = JCM 1192 BAR00515.1     44
 B7017_1627   Bifidobacterium breve JCM 7017 AHJ17874.1     44
 B7019_1610   Bifidobacterium breve JCM 7019 AHJ19787.1     44
 BBL520_07960   Bifidobacterium breve LMC520 AQM43480.1     44
 B2258_1417   Bifidobacterium breve NCFB 2258 AHJ21603.1     44
 NRBB01_1492   Bifidobacterium breve NRBB01 AUD67695.1     44
 NRBB02_1449   Bifidobacterium breve NRBB02 AUD69543.1     44
 NRBB04_1425   Bifidobacterium breve NRBB04 AUD71384.1     44
 NRBB08_1451   Bifidobacterium breve NRBB08 AUE07754.1     44
 NRBB09_1451   Bifidobacterium breve NRBB09 AUD73289.1     44
 NRBB11_1445   Bifidobacterium breve NRBB11 AUD75167.1     44
 NRBB18_1452   Bifidobacterium breve NRBB18 AUE09628.1     44
 NRBB19_1453   Bifidobacterium breve NRBB19 AUE11505.1     44
 NRBB20_1459   Bifidobacterium breve NRBB20 AUE13380.1     44
 NRBB27_1450   Bifidobacterium breve NRBB27 AUE15252.1     44
 NRBB49_1451   Bifidobacterium breve NRBB49 AUE17120.1     44
 NRBB50_1619   Bifidobacterium breve NRBB50 AUD77235.1     44
 NRBB51_1525   Bifidobacterium breve NRBB51 AUD81609.1     44
 NRBB52_1506   Bifidobacterium breve NRBB52 AUD83557.1     44
 NRBB56_1514   Bifidobacterium breve NRBB56 AUD85540.1     44
 NRBB57_1717   Bifidobacterium breve NRBB57 AUD87708.1     44
 BS27_1462   Bifidobacterium breve S27 AHJ25238.1     44
 Bbr_1438   Bifidobacterium breve UCC2003 ABE96110.1     44
 BBCT_1303   Bifidobacterium catenulatum DSM 16992 = JCM 1194 = LMG 11043 BAR02271.1     44
 BBCT_1301   Bifidobacterium catenulatum DSM 16992 = JCM 1194 = LMG 11043 BAR02269.1     44
 BDP_1678   Bifidobacterium dentium Bd1 ADB10270.1 D2Q5Q5   44
 BDP_1679   Bifidobacterium dentium Bd1 ADB10271.1 D2Q5Q6   44
 BBDE_1592   Bifidobacterium dentium JCM 1195 = DSM 20436 BAQ27586.1     44
 BBDE_1593   Bifidobacterium dentium JCM 1195 = DSM 20436 BAQ27587.1     44
 BBKW_1501   Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 BAQ29636.1     44
 AH68_07950   Bifidobacterium kashiwanohense PV20-2 AIZ14998.1     44
 AH68_07940   Bifidobacterium kashiwanohense PV20-2 AIZ14996.1     44
 BL105A_1466   Bifidobacterium longum 105-A BAP84090.1     44
 B624_1382   Bifidobacterium longum 35624 AOL10833.1     44
 BBG7_1592   Bifidobacterium longum BG7 ALE36779.1     44
 GS08_07990   Bifidobacterium longum BXY01 AIF91045.1     44
 BLD_1938 (BglC)   Bifidobacterium longum DJO10A ACD99383.1     44
 BL1761   Bifidobacterium longum NCC2705 AAN25544.1
NP_696908.1
Q8G3J8   44
 SAMN04489749_0603   Bifidobacterium longum Su859 SDO39948.1     44
 BLIF_1557   Bifidobacterium longum subsp. infantis 157F BAJ71695.1     44
 Blon_0621   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 ACJ51728.1 B7GPJ8   44
 BLIJ_0626   Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088 BAJ68219.1     44
 RY67_1342   Bifidobacterium longum subsp. infantis BT1 ALE09362.1     44
 BL1206_1618   Bifidobacterium longum subsp. longum AH1206 AOP01655.1     44
 BBMN68_1793   Bifidobacterium longum subsp. longum BBMN68 ADQ02850.1 E4R3Z1   44
 BBL306_1734   Bifidobacterium longum subsp. longum CCUG30698 ALO75263.1     44
 BIL_02210   Bifidobacterium longum subsp. longum F8 CBK69899.1 D6DBM8   44
 BLGT_08000   Bifidobacterium longum subsp. longum GT15 AIW44128.1     44
 BLLJ_1498 (possible fragment)   Bifidobacterium longum subsp. longum JCM 1217 BAJ67165.1     44
 BLJ_1536   Bifidobacterium longum subsp. longum JDM301 ADH00979.1 D6ZVS3   44
 BLNIAS_00618   Bifidobacterium longum subsp. longum KACC 91563 AEI96988.1     44
 B8809_1374   Bifidobacterium longum subsp. longum NCIMB8809 ALO73045.1     44
 BIP_14810   Bifidobacterium pseudocatenulatum D2CA CBK72652.1     44
 BBPC_1381   Bifidobacterium pseudocatenulatum DSM 20438 = JCM 1200 = LMG 10505 BAR04059.1     44
 BBPC_1383   Bifidobacterium pseudocatenulatum DSM 20438 = JCM 1200 = LMG 10505 BAR04061.1     44
 BBSC_1966   Bifidobacterium scardovii JCM 12489 = DSM 13734 BAQ32046.1     44
 D805_0070 (fragment)   Bifidobacterium thermophilum RBL67 AGH40337.1     44
 ADH70_005020   Blautia coccoides YL58 ASU28285.1     44
 A4V09_06660   Blautia sp. YL58 ANU75476.1     44
 C3348_00450   Clostridioides difficile 08-00495 AVB48152.1     44
 TW87_02815   Clostridioides difficile 08ACD0030 AMM55516.1     44
 C3353_00450   Clostridioides difficile 09-00072 AVB59085.1     44
 C3349_00450   Clostridioides difficile 10-00071 AVB55458.1     44
 C3351_00450   Clostridioides difficile 10-00078 AVB62714.1     44
 C3352_00455   Clostridioides difficile 10-00253 AVB66249.1     44
 C3347_00450   Clostridioides difficile 12-00008 AVB32210.1     44
 C3350_00450   Clostridioides difficile 12-00011 AVB51834.1     44
 CD0032   Clostridioides difficile 630 CAJ66846.1
AJP09721.1
Q18CC0   44
 CDIF630erm_00094 (ExgA)   Clostridioides difficile 630 delta erm ARE60931.1     44
 CD630DERM_00320   Clostridioides difficile 630Derm CEJ96534.1     44
 C4J70_18570   Clostridioides difficile AK AVI14157.1     44
 CDIF1296T_00094   Clostridioides difficile ATCC 9689 = DSM 1296 AKP41043.1     44
 BZ168_18160   Clostridioides difficile BR81 AQU11467.1     44
 C3W74_00450   Clostridioides difficile CD-10-00484 AVB39551.1     44
 DDG63_00450   Clostridioides difficile CD161 AWH79575.1     44
 CD196_0033   Clostridioides difficile CD196 CBA60100.1 C9XIE4   44
 DDG61_00450   Clostridioides difficile CDT4 AWH75764.1     44
 CGC51_00450   Clostridioides difficile DH/NAP11/106/ST-42 ASN87869.1     44
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