Glycoside Hydrolase Family 5 / Subf 42

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (60); Uniprot accession (4);
All (60) Bacteria (60)
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 APS56_15690   Algibacter alginicilyticus HZ22 ALJ06487.1     42
 Celal_3054   Cellulophaga algicola DSM 14237 ADV50329.1     42
 M666_11930   Cellulophaga baltica 18 AIZ42235.1     42
 M667_11885   Cellulophaga baltica NN016038 AIY13855.1     42
 A5M85_06630   Cellulophaga lytica DAU203 APU09967.1     42
 Celly_1230   Cellulophaga lytica DSM 7489 ADY29058.1     42
 IX49_06035   Cellulophaga lytica HI1 AIM60100.1     42
 SAMN06298216_2174   Cytophagales bacterium TFI 002 SOE21718.1     42
 I597_1863   Dokdonia donghaensis DSW-1 ANH60765.1     42
 Krodi_2393   Dokdonia sp. 4H-3-7-5 AEE20371.1     42
 MED134_06729   Dokdonia sp. MED134 EAQ40429.1     42
 AWN65_00150   Flavobacterium columnare 94-081 AMA47982.1     42
 FCOL_08425   Flavobacterium columnare ATCC 49512 AEW86500.1     42
 UN65_08770   Flavobacterium columnare B185 AMO20418.1     42
 AX766_05310   Flavobacterium columnare C#2 AND63875.1     42
 Pf1_01440   Flavobacterium columnare Pf1 ANO49681.1     42
 BU993_06955   Flavobacterium columnare TC 1691 APT22385.1     42
 IY34_04485   Flavobacterium psychrophilum 3 AKC28454.1     42
 SU65_04775   Flavobacterium psychrophilum 4 AKC16762.1     42
 IY36_04765   Flavobacterium psychrophilum 5 AKC19086.1     42
 IB65_04310   Flavobacterium psychrophilum 950106-1/1 AIT65126.1     42
 FPSM_01338   Flavobacterium psychrophilum CSF259-93 AIJ37833.1     42
 FPG101_06595   Flavobacterium psychrophilum FPG101 AIN71599.1     42
 FPG3_10435   Flavobacterium psychrophilum FPG3 AIN74671.1     42
 FP0938   Flavobacterium psychrophilum JIP02/86 CAL43032.1 A6GY59   42
 IY37_04770   Flavobacterium psychrophilum MH1 AKC21454.1     42
 THC0290_1256   Flavobacterium psychrophilum OSU THCO2-90 SHH95027.1     42
 IY38_04780   Flavobacterium psychrophilum PG2 AKC23826.1     42
 IA01_04415   Flavobacterium psychrophilum V1-20 AIG32030.1     42
 IA02_03820   Flavobacterium psychrophilum V2-20 AIG34185.1     42
 IA03_04400   Flavobacterium psychrophilum V3-5 AIG29753.1     42
 IA04_04315   Flavobacterium psychrophilum V4-24 AIG36548.1     42
 IA05_04400   Flavobacterium psychrophilum V4-28 AIG38813.1     42
 IA06_04350   Flavobacterium psychrophilum V4-33 AIG41079.1     42
 IY39_04485   Flavobacterium psychrophilum VQ50 AKC26140.1     42
 FORMB_08760   Formosa sp. Hel1_33_131 AOR27927.1     42
 SAMN04487764_0677   Gillisia sp. Hel1_33_143 SDR79299.1     42
 GRFL_2276   Gramella flava JLT2011 APU69000.1     42
 Haur_2181   Herpetosiphon aurantiacus DSM 785 ABX04821.1 A9AX13   42
 Lacal_1347   Lacinutrix sp. 5H-3-7-4 AEH01195.1     42
 BWR22_04520   Lacinutrix venerupis DOK2-8 APX99604.1     42
 YQ22_14015   Maribacter sp. 1_2014MBL_MicDiv APA65335.1     42
 FB2170_03475   Maribacter sp. HTCC2170 EAR02312.1 A4AMU0   42
 SAMN05192545_2140   Maribacter sp. MAR_2009_60 SDS82312.1     42
 DDD_2752   Nonlabens dokdonensis DSW-6 AGC77879.1     42
 BST91_11510   Nonlabens sediminis NBRC 100970 ARN72242.1     42
 SAMN05192588_0623   Nonlabens sp. Hel1_33_55 SCX99337.1     42
 AAT17_07300   Nonlabens sp. MIC269 ALM21040.1     42
 BXQ17_03630   Polaribacter sp. BM10 AQS93222.1     42
 MED152_03120   Polaribacter sp. MED152 EAQ41672.3     42
 BTO04_01600   Polaribacter sp. SA4-10 ARV05465.1     42
 BTO07_04235   Polaribacter sp. SA4-12 ARV14404.1     42
 P700755_001511   Psychroflexus torquis ATCC 700755 AFU68400.1     42
 SB49_06355   Sediminicola sp. YIK13 ALM07466.1     42
 AUW17_07165   Tenacibaculum dicentrarchi AY7486TD ALU76135.1     42
 TJEJU_2824   Tenacibaculum jejuense KCTC 22618 SNR16498.1     42
 AXE80_11690   Wenyingzhuangia fucanilytica CZ1127 ANW96905.1     42
 BTO05_11285   Winogradskyella sp. PC-19 ARV10190.1     42
 zobellia_2986   Zobellia galactanivorans DsiJT CAZ97132.1     42
 ZPR_1048   Zunongwangia profunda SM-A87 ADF51393.1 D5BI05   42
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