Glycoside Hydrolase Family 5 / Subf 38

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (28); Uniprot accession (8);
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 cellodextrinase (UmCel5Q) (UmCel5Q)   uncultured microorganism ADB80112.1 D3JVU3   38
 cellodextrinase (UmCel5O) (Cel5O)   uncultured microorganism ADB80113.1 D3JVU4   38
 β-glucanase (M40-2) 3.2.1.- uncultured microorganism ACA61171.1 B1PLL4   38
 SARM_0054 / 1557092_108510 / MH-18 uncultured organism ADX05725.1     38
 SARM_0046 / 1029836_111030 / MH-2 uncultured organism ADX05717.1     38
 SARM_0004 / 3671981_90060 / MH-13 (fragment)   uncultured organism ADX05675.1     38
 exo-cellulase (CelEx-BR12) 3.2.1.- uncultured organism AGK74985.1     38

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