Glycoside Hydrolase Family 5 / Subf 37

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (37); Uniprot accession (15); PDB accession (3); 3D entries (1); cryst (0)
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 endoglucanase (umCel5N) uncultured microorganism ACH67609.1 B5LZ80   37
 cellulase   uncultured microorganism AOA60286.1     37
 cellulase   uncultured microorganism AOA60285.1     37
 cellulase (DM1-1) 3.2.1.- uncultured microorganism ACA61162.1 B1PLK5   37
 β-glucanase (M8-2) 3.2.1.- uncultured microorganism ACA61165.1 B1PLK8   37
 β-glucanase 3.2.1.- uncultured organism ADD61786.1 D9ZEN2   37
 SARM_0068 / 3004993_158220 / TW-3 uncultured organism ADX05739.1     37

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