Glycoside Hydrolase Family 5 / Subf 37

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (37); Uniprot accession (15); PDB accession (3); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 endoglucanase (Glu1E)   Alicyclobacillus tengchongensis CGMCC 1504 AJD08472.1     37
 ANT_03660   Anaerolinea thermophila UNI-1 BAJ62400.1     37
 endo-β-1,4-glucanase C307 (CelC307) 3.2.1.4 Clostridium sp. F1 BAA00793.1 P23340   37
 CCU_08490   Coprococcus sp. ART55/1 CBK82603.1 D5HIJ8   37
 EUS_04280   [Eubacterium] siraeum 70/3 CBK95738.1 D4JRL9   37
 ES1_10060   [Eubacterium] siraeum V10Sc8a CBL34054.1 D4MJX1   37
 SD1D_1744 (Celc307)   Herbinix luporum SD1D CUH93289.1     37
 R50912_24910   Paenibacillus sp. FSL R5-0912 AIQ42917.1     37
 PSTEL_08595 (fragment)   Paenibacillus stellifer DSM 14472 AIQ63143.1     37
 AD2_00399   Ruminiclostridium thermocellum AD2 ALX07407.1     37
 Cthe_2807 (CelC)   Ruminiclostridium thermocellum ATCC 27405 ABN54006.1 A3DJ77   37
 Clo1313_0395   Ruminiclostridium thermocellum DSM 1313 ADU73485.1     37
 LQRI_0399   Ruminiclostridium thermocellum DSM 2360 LQRI ANV75146.1     37
 endo-β-1,4-glucanase C (CelC) 3.2.1.4 Ruminiclostridium thermocellum F7 CAC27410.1 Q9AL36   37
 endo-β-1,4-glucanase C (LC2;CelC;EgC) (Cel5B) 3.2.1.4 Ruminiclostridium thermocellum NCIB 10682EL AAA23220.1 P07985
P0C2S3
1CEC[A]
1CEN[A]
1CEO[A]
37
 Rumal_1792   Ruminococcus albus 7 = DSM 20455 ADU22290.1 E0L4H4   37
 lichenase (Ra0453;CUS_6741) (β-1,3-specific;cellobiose releasing) 3.2.1.73 Ruminococcus albus 8 ZP_08159266.1
EGC02962.1
    37
 RBI_II00453   Ruminococcus bicirculans 80/3 CCO06210.1     37
 cellodextrinase (CelA) 3.2.1.74 Ruminococcus flavefaciens FD-1 CAA36207.1 P16169   37
 Tresu_2549   Treponema succinifaciens DSM 2489 AEB15411.1     37
 endo-β-1,4-glucanase / acidic cellulase (En1;CMC01D10-ORF18) 3.2.1.4 uncultured bacterium AEV59734.1     37
 Scaffold00024.3 (En4) 3.2.1.- uncultured bacterium AEV59731.1     37
 Exo_contig136_11 (En6) 3.2.1.- uncultured bacterium AEV59739.1     37
 ORF   uncultured bacterium Contig1468_n_1482_cl AHF26427.1     37
 endoglucanase 3.2.1.4 uncultured bacterium Contig15 AHF23845.1     37
 ORF   uncultured bacterium Contig27 AHF24623.1     37
 ORF   uncultured bacterium Contig52 AHF25090.1     37
 ORF   uncultured bacterium Contigcl_1149 AHF25829.1     37
 endo-β-1,4-glucanase (CelA;Cel) 3.2.1.4 unidentified bacterium AAA91966.1 Q60054   37
Top




Last update: 2017-10-09 © Copyright 1998-2017
AFMB - CNRS - Université d'Aix-Marseille