Glycoside Hydrolase Family 5 / Subf 35

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (15); Uniprot accession (4);
All (15) Bacteria (15)
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 BBD41_26930   Paenibacillus ihbetae IHBB 9852 ANY75917.1     35
 PPE_04163   Paenibacillus polymyxa E681 ADM71943.1 E0RF27   35
 AOU00_09155   Paenibacillus polymyxa J AOK89969.1     35
 PPM_2417 (CelE1)   Paenibacillus polymyxa M1 CCC85354.1     35
 RE92_24165   Paenibacillus polymyxa Sb3-1 AJE53934.1     35
 PPSC2_c2687   Paenibacillus polymyxa SC2 ADO56655.1 E3E4B5   35
 BBD42_28615   Paenibacillus sp. BIHB4019 ANY70024.1     35
 BBD42_24990   Paenibacillus sp. BIHB4019 ANY69377.1     35
 DCC85_10935   Paenibacillus sp. CAA11 AWB46909.1     35
 R50912_13105   Paenibacillus sp. FSL R5-0912 AIQ40861.1     35
 Pjdr2_4271   Paenibacillus sp. JDR-2 ACT02895.1 C6D792   35
 C0638_20495   Paenibacillus sp. lzh-N1 AUO08763.1     35
 EGM68_12965   Paenibacillus sp. M-152 AZH29603.1     35
 ORF1   Paenibacillus sp. W-61 BAF49076.1 A4F258   35
 BS614_18655   Paenibacillus xylanexedens PAMC 22703 APO45845.1     35

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