Glycoside Hydrolase Family 5 / Subf 35

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (12); Uniprot accession (4);
All (12) Bacteria (12)
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 BBD41_26930   Paenibacillus ihbetae IHBB 9852 ANY75917.1     35
 PPE_04163   Paenibacillus polymyxa E681 ADM71943.1 E0RF27   35
 AOU00_09155   Paenibacillus polymyxa J AOK89969.1     35
 PPM_2417 (CelE1)   Paenibacillus polymyxa M1 CCC85354.1     35
 RE92_24165   Paenibacillus polymyxa Sb3-1 AJE53934.1     35
 PPSC2_c2687   Paenibacillus polymyxa SC2 ADO56655.1 E3E4B5   35
 BBD42_28615   Paenibacillus sp. BIHB4019 ANY70024.1     35
 BBD42_24990   Paenibacillus sp. BIHB4019 ANY69377.1     35
 R50912_13105   Paenibacillus sp. FSL R5-0912 AIQ40861.1     35
 Pjdr2_4271   Paenibacillus sp. JDR-2 ACT02895.1 C6D792   35
 ORF1   Paenibacillus sp. W-61 BAF49076.1 A4F258   35
 BS614_18655   Paenibacillus xylanexedens PAMC 22703 APO45845.1     35
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