Glycoside Hydrolase Family 5 / Subf 33

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (35); Uniprot accession (7);
All (35) Eukaryota (35)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ALNC14_088050 (Alnc14c163g7812) (possible fragment)   Albugo laibachii Nc14 CCA22662.1     33
 ALNC14_127210   Albugo laibachii Nc14 CCA26577.1     33
 ALNC14_139410 (Alnc14c693g12405)   Albugo laibachii Nc14 CCA27797.1     33
 Esi_0054_0103   Ectocarpus siliculosus Ec 32 CBJ27054.1     33
 exo-β-1,3-glucanase 1 (Exo1;PiExo1)   Phytophthora infestans AAM18483.1 Q8S315   33
 exo-β-1,3-glucanase 2 (Exo2;PiExo2) (fragment)   Phytophthora infestans AAM18485.1 Q8S313   33
 PITG_10218   Phytophthora infestans T30-4 EEY56664.1     33
 PITG_09799   Phytophthora infestans T30-4 EEY55816.1     33
 PHYSODRAFT_562400   Phytophthora sojae P6497 EGZ13975.1     33
 PHYSODRAFT_547331   Phytophthora sojae P6497 EGZ13976.1     33
 PHYSODRAFT_535774   Phytophthora sojae P6497 EGZ04731.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75368.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75360.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75351.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75358.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75364.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75356.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75353.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75361.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75359.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75367.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75366.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75365.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75357.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75354.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75355.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum AMT75352.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum ATCC 58637 AMT75369.1     33
 exo-1,3-beta glucanase, partial (Exo1) (fragment)   Pythium insidiosum CBS 119452 AMT75370.1     33
 ORF (fragment)   Pythium insidiosum P01 ADI86640.1 D9DBT4   33
 ORF (fragment)   Pythium insidiosum P07 ADI86644.1 D9DBT8   33
 ORF (fragment)   Pythium insidiosum P17 ADI86650.1 D9DBU4   33
 ORF (fragment)   Pythium insidiosum P22 ADI86653.1 D9DBU7   33
 ORF (fragment)   Pythium insidiosum P24 ADI86654.1 D9DBU8   33
 exo-1,3-beta glucanase, partial (Pinsexo1)   Pythium insidiosum Pi24 BAS04784.1     33
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