Glycoside Hydrolase Family 5 / Subf 30

Activities in Familyendo-β-1,4-glucanase / cellulase (EC; endo-β-1,4-xylanase (EC; β-glucosidase (EC; β-mannosidase (EC; β-glucosylceramidase (EC; glucan β-1,3-glucosidase (EC; licheninase (EC; exo-β-1,4-glucanase / cellodextrinase (EC; glucan endo-1,6-β-glucosidase (EC; mannan endo-β-1,4-mannosidase (EC; cellulose β-1,4-cellobiosidase (EC; steryl β-glucosidase (EC; endoglycoceramidase (EC; chitosanase (EC; β-primeverosidase (EC; xyloglucan-specific endo-β-1,4-glucanase (EC; endo-β-1,6-galactanase (EC; hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC; β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (7); Uniprot accession (0);
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 CC1G_04257   Coprinopsis cinerea okayama7#130 EAU88551.2     30
 CC1G_02860   Coprinopsis cinerea okayama7#130 EAU93630.1     30
 LACBIDRAFT_292256   Laccaria bicolor S238N-H82 EDR14294.1     30
 LACBIDRAFT_294893 (fragment)   Laccaria bicolor S238N-H82 EDR05274.1     30
 PIIN_01733   Serendipita indica DSM 11827 CCA78057.1     30
 SERLA73DRAFT_191077   Serpula lacrymans var. lacrymans S7.3 EGN92442.1     30
 SERLADRAFT_480672   Serpula lacrymans var. lacrymans S7.9 EGO18569.1     30

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