Glycoside Hydrolase Family 5 / Subf 29

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (20); Uniprot accession (3);
Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ATC03_16595   Agromyces aureus AR33 ANJ28089.1     29
 SAMN04489834_1755   Microterricola viridarii DSM 21772 SDS58964.1     29
 AWU67_04485   Microterricola viridarii ERGS5:02 AMB58227.1     29
 NS506_00675   Nocardia seriolae EM150506 APA94754.1     29
 NSERUTF1_0046   Nocardia seriolae UTF1 BAW03318.1     29
 XU06_12465   Rhodococcus erythropolis BG43 AKD97460.1     29
 O5Y_12270   Rhodococcus erythropolis CCM2595 AGT92316.1     29
 RER_26700   Rhodococcus erythropolis PR4 BAH33378.1 C0ZYE3   29
 H351_20065   Rhodococcus erythropolis R138 ALU71366.1     29
 RHOER0001_5859   Rhodococcus erythropolis SK121 EEN88042.1     29
 REQ_10740   Rhodococcus hoagii 103S CBH47174.1 E4WE20   29
 HMPREF0724_4416   Rhodococcus hoagii ATCC 33707 EFG59858.1     29
 oligogalactosyl-N-acylsphingosine 1,1-β-galactohydrolase / endogalactosylceramidase / endoglycoceramidase III (EGalC;EGCase III) 3.2.1.123 Rhodococcus hoagii M-750 BAF56440.1 A4PCI3   29
 AOT96_23705   Rhodococcus sp. 008 ANQ73510.1     29
 A0W34_12605   Rhodococcus sp. BH4 ARE34060.1     29
 CPI83_16535   Rhodococcus sp. H-CA8f ATI33475.1     29
 BTZ20_3595   Rhodococcus sp. MTM3W5.2 AQA21940.1     29
 BTZ20_3739 (fragment)   Rhodococcus sp. MTM3W5.2 AQA22793.1     29
 BTZ20_4493   Rhodococcus sp. MTM3W5.2 AQA25521.1     29
 BTZ20_1119 (fragment)   Rhodococcus sp. MTM3W5.2 AQA20950.1     29
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