Activities in Sub Family	Endoglycosylceramidase (EC 3.2.1.123);
Mechanism	Retaining e
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resources	CAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (4); Uniprot accession (2); PDB accession (6); 3D entries (1); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
endoglycoceramidase II (EGCase II; M777_EGCase II)	3.2.1.123	Rhodococcus sp. (in: high G+C Gram-positive bacteria) M-777	AAB67050.1	O33853	2OSW[A,B] 1.60 2OSX[A] α-D-Neup5Ac-(2-3)-β-D-Galp-(1-4)-β-D-Glcp-(1-1)-<non_carb> 1.10 2OSY[A,B] β-D-Galp-(1-4)-α-D-Glcp-(1-4)-GLU 2.10 2OYK[A,B] β-D-Glcp-(1-1)-<non_carb> 1.50 2OYL[A,B] β-D-Glcp-(1-1)-<non_carb> 1.80 2OYM[A,B] <carb_like_MNI> 1.86	28
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