Glycoside Hydrolase Family 5 / Subf 20

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (39); Uniprot accession (20);
All (28) Eukaryota (28)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 ALNC14_005500 (Alnc14c3g505)   Albugo laibachii Nc14 CCA14407.1     20
 ALNC14_011460 (Alnc14c7g1004)   Albugo laibachii Nc14 CCA15003.1
CCA25494.1
    20
 ALNC14_057660 (Alnc14c75g5042)   Albugo laibachii Nc14 CCA19623.1
CCA22873.1
    20
 ALNC14_059470 (Alnc14c79g5216)   Albugo laibachii Nc14 CCA19804.1     20
 ALNC14_100670 (Alnc14c213g8963)   Albugo laibachii Nc14 CCA23923.1     20
 ALNC14_127450 (Alnc14c394g11305)   Albugo laibachii Nc14 CCA26601.1     20
 ALNC14_136230 (Alnc14c546g12117)   Albugo laibachii Nc14 CCA27479.1     20
 endo-β-1,4-glucanase (EGL-V.1)   Phytophthora infestans ABG76934.1 Q0PRJ9   20
 endo-β-1,4-glucanase (EGL-V.5)   Phytophthora infestans ABJ55764.1
ABJ55765.1
A0A1I3   20
 endo-β-1,4-glucanase (EGL-V.4)   Phytophthora infestans ABJ97692.1 A0FH79   20
 endo-β-1,4-glucanase (EGL-V.6)   Phytophthora infestans ABL75351.1 A1YT28   20
 endo-β-1,4-glucanase (EGL-V.7)   Phytophthora infestans ABL75352.1 A1YT29   20
 endo-β-1,4-glucanase (EGL-V.2)   Phytophthora ramorum ABG80550.1
ABG80551.1
Q0PN02   20
 endo-β-1,4-glucanase (EGL-V.1)   Phytophthora ramorum ABG80552.1
ABG80553.1
Q0PN00   20
 endo-β-1,4-glucanase (EGL-V.3)   Phytophthora ramorum ABG80554.1
ABG80555.1
Q0PMZ8   20
 endo-β-1,4-glucanase (EGL-V.6)   Phytophthora ramorum ABL75348.1 A1YT25   20
 endo-β-1,4-glucanase (EGL-V.4)   Phytophthora ramorum ABL75349.1 A1YT26   20
 endo-β-1,4-glucanase (EGL-V.5)   Phytophthora ramorum ABL75350.1 A1YT27   20
 endo-β-1,4-glucanase (EGL-V.1)   Phytophthora sojae ABC87086.1 Q2I0L5   20
 endo-β-1,4-glucanase (EGL-V.2)   Phytophthora sojae ABC87087.1
ABK59035.1
Q2I0L4   20
 endo-β-1,4-glucanase (EGL-V.3)   Phytophthora sojae ABC87088.1 Q2I0L3   20
 endo-β-1,4-glucanase (EGL-V.5)   Phytophthora sojae ABC87089.1
ABK59036.1
Q2I0L2   20
 endo-β-1,4-glucanase (EGL-V.7)   Phytophthora sojae ABC87090.1
ABK59037.1
Q2I0L1   20
 endo-β-1,4-glucanase (EGL-V.8) (Cel5A)   Phytophthora sojae ABC87091.1
ABK59038.1
Q2I0L0   20
 endo-β-1,4-glucanase (EGL-V.4)   Phytophthora sojae ABC87092.1 Q2I007   20
 endo-β-1,4-glucanase (EGL-V.6) (fragment)   Phytophthora sojae ABJ97449.1
ABJ97450.1
A0FEW9   20
 endo-β-1,4-glucanase (EGL-V.9)   Phytophthora sojae ABL75347.1 A1YT24   20
 ORF (fragment)   Plasmopara viticola CCD28218.1     20
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