| Activities in Sub Family | Endo-β-1,4-glucanase (EC 3.2.1.4); Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73); Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
| External resources | CAZypedia; HOMSTRAD; PROSITE; |
| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
| Statistics | GenBank accession (60); Uniprot accession (36); PDB accession (16); 3D entries (4); cryst (0) |
| Archaea | ||||||||
| Protein Name | EC# | Organism | GenBank | Uniprot | PDB/3D | Subf | ||
| Igag_0570 | Ignisphaera aggregans DSM 17230 | ADM27405.1 | 1 | |||||
| Igag_0224 | Ignisphaera aggregans DSM 17230 | ADM27073.1 | 1 | |||||
| IG193_01325 | Infirmifilum lucidum 3507LT | QOJ79134.1 | 1 | |||||
| MOV14_09510 | Infirmifilum sp. NZ | UNQ73334.1 | 1 | |||||
| endo-β-1,4-glucanase (EglB;TCel4;PAB0632) | 3.2.1.4 | Pyrococcus abyssi GE5 | CAB49854.1 AEG76944.1 NP_126623.1 |
Q9V052 | 1 | |||
| endo-β-1,4-glucanase (EGPh;EglB;TCel3;PH1171) | 3.2.1.4 | Pyrococcus horikoshii OT3 | AAQ31833.1 AAQ31832.1 BAA30271.1 NP_143072.1 |
O58925 | 2ZUM[A] 2ZUN[A,B,C] 3AXX[A,B,C] 3QHM[A,B,C] 3QHN[A,B,C] 3QHO[A,B,C] 3VVG[A,B,C] 3W6L[A,B,C] 3W6M[A,B,C] 4DM1[A,B,C] 4DM2[A,B,C] |
1 | ||
| Py04_1787 | Pyrococcus sp. ST04 | AFK23355.1 | 1 | |||||
| Shell_0798 | Staphylothermus hellenicus DSM 12710 | ADI31911.1 | 1 | |||||
| CHITON_2145 | Thermococcus chitonophagus DSM 10152 | CUX78924.1 | 1 | |||||
| A3L04_02950 | Thermococcus chitonophagus GC74 | ASJ17552.1 | 1 | |||||
| ADU37_CDS22600 | Thermococcus sp. 2319x1 | ALV63957.1 | 1 | |||||
| endo-β-1,4-glucanase (Cel5A; Vul_Cel5A) | 3.2.1.4 | uncultured archaeon | AZP54316.1 | A0A3Q9CZQ1 | 1 | |||
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