Glycoside Hydrolase Family 5 / Subf 12

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Activities in Sub Family
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (241); Uniprot accession (33);
All (231) Bacteria (40) Eukaryota (191) Characterized (5)
| 1 | 2 |
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 H813_YJM1402I00183   Saccharomyces cerevisiae YJM1402 AJR49622.1     12
 H814_YJM1415I00180   Saccharomyces cerevisiae YJM1415 AJR49816.1     12
 H815_YJM1417I00184   Saccharomyces cerevisiae YJM1417 AJR50005.1     12
 H816_YJM1418I00182   Saccharomyces cerevisiae YJM1418 AJR50193.1     12
 H817_YJM1419I00185   Saccharomyces cerevisiae YJM1419 AJR50384.1     12
 H818_YJM1433I00187   Saccharomyces cerevisiae YJM1433 AJR50578.1     12
 H819_YJM1434I00181   Saccharomyces cerevisiae YJM1434 AJR50770.1     12
 H820_YJM1439I00179   Saccharomyces cerevisiae YJM1439 AJR50963.1     12
 H821_YJM1443I00181   Saccharomyces cerevisiae YJM1443 AJR51151.1     12
 H822_YJM1444I00184   Saccharomyces cerevisiae YJM1444 AJR51342.1     12
 H823_YJM1447I00178   Saccharomyces cerevisiae YJM1447 AJR51519.1     12
 H824_YJM1450I00182   Saccharomyces cerevisiae YJM1450 AJR51714.1     12
 H825_YJM1460I00172   Saccharomyces cerevisiae YJM1460 AJR51899.1     12
 H826_YJM1463I00183   Saccharomyces cerevisiae YJM1463 AJR52092.1
AJR52092.1
    12
 H827_YJM1477I00180   Saccharomyces cerevisiae YJM1477 AJR52285.1     12
 H828_YJM1478I00182   Saccharomyces cerevisiae YJM1478 AJR52473.1     12
 H829_YJM1479I00183   Saccharomyces cerevisiae YJM1479 AJR52665.1     12
 H830_YJM1526I00109   Saccharomyces cerevisiae YJM1526 AJR52782.1     12
 H831_YJM1527I00186   Saccharomyces cerevisiae YJM1527 AJR52976.1     12
 H832_YJM1549I00186   Saccharomyces cerevisiae YJM1549 AJR53172.1     12
 H833_YJM1573I00184   Saccharomyces cerevisiae YJM1573 AJR53358.1     12
 H834_YJM1574I00184   Saccharomyces cerevisiae YJM1574 AJR53552.1     12
 H835_YJM1592I00180   Saccharomyces cerevisiae YJM1592 AJR53745.1     12
 H836_YJM1615I00179   Saccharomyces cerevisiae YJM1615 AJR45111.1     12
 H747_YJM189I00187   Saccharomyces cerevisiae YJM189 AJR36765.1     12
 H748_YJM193I00186   Saccharomyces cerevisiae YJM193 AJR36959.1     12
 H750_YJM244I00187   Saccharomyces cerevisiae YJM244 AJR37299.1     12
 H751_YJM248I00182   Saccharomyces cerevisiae YJM248 AJR37491.1     12
 H752_YJM270I00183   Saccharomyces cerevisiae YJM270 AJR37685.1     12
 H753_YJM271I00183   Saccharomyces cerevisiae YJM271 AJR37881.1     12
 H754_YJM320I00171   Saccharomyces cerevisiae YJM320 AJR38062.1     12
 H755_YJM326I00181   Saccharomyces cerevisiae YJM326 AJR38253.1     12
 H756_YJM428I00180   Saccharomyces cerevisiae YJM428 AJR38446.1     12
 H757_YJM450I00181   Saccharomyces cerevisiae YJM450 AJR38639.1     12
 H758_YJM451I00183   Saccharomyces cerevisiae YJM451 AJR38829.1     12
 H759_YJM453I00180   Saccharomyces cerevisiae YJM453 AJR39024.1
AJR39024.1
    12
 H760_YJM456I00183   Saccharomyces cerevisiae YJM456 AJR39216.1     12
 H761_YJM470I00177   Saccharomyces cerevisiae YJM470 AJR39401.1     12
 H762_YJM541I00176   Saccharomyces cerevisiae YJM541 AJR39583.1     12
 H763_YJM554I00176   Saccharomyces cerevisiae YJM554 AJR39762.1     12
 H764_YJM555I00181   Saccharomyces cerevisiae YJM555 AJR39953.1     12
 H765_YJM627I00182   Saccharomyces cerevisiae YJM627 AJR40146.1     12
 H766_YJM681I00177   Saccharomyces cerevisiae YJM681 AJR40334.1     12
 H767_YJM682I00186   Saccharomyces cerevisiae YJM682 AJR40526.1     12
 H768_YJM683I00182   Saccharomyces cerevisiae YJM683 AJR40720.1     12
 H769_YJM689I00175   Saccharomyces cerevisiae YJM689 AJR40900.1
AJR40900.1
    12
 H770_YJM693I00165   Saccharomyces cerevisiae YJM693 AJR41072.1     12
 H771_YJM969I00179   Saccharomyces cerevisiae YJM969 AJR41266.1     12
 H772_YJM972I00187   Saccharomyces cerevisiae YJM972 AJR41460.1     12
 H773_YJM975I00180   Saccharomyces cerevisiae YJM975 AJR41653.1     12
 H774_YJM978I00184   Saccharomyces cerevisiae YJM978 AJR41847.1     12
 H775_YJM981I00179   Saccharomyces cerevisiae YJM981 AJR42040.1     12
 H776_YJM984I00183   Saccharomyces cerevisiae YJM984 AJR42230.1     12
 H777_YJM987I00180   Saccharomyces cerevisiae YJM987 AJR42424.1     12
 H778_YJM990I00179   Saccharomyces cerevisiae YJM990 AJR42618.1     12
 H779_YJM993I00180   Saccharomyces cerevisiae YJM993 AHY76004.1
AHY76004.1
    12
 H780_YJM996I00185   Saccharomyces cerevisiae YJM996 AJR42812.1     12
 AACERI_AaceriAAR017W   Saccharomycetaceae sp. Ashbya aceri AGO10007.1     12
 PICST_55209   Scheffersomyces stipitis CBS 6054 ABN65235.1
ABN65235.2
    12
 sscle_12g090890   Sclerotinia sclerotiorum 1980 UF-70 APA14319.1     12
 PIIN_08376   Serendipita indica DSM 11827 CCA74424.1     12
 PIIN_09732   Serendipita indica DSM 11827 CCA75742.1     12
 sr11602   Sporisorium reilianum SRZ2 CBQ67652.1     12
 sr14731   Sporisorium reilianum SRZ2 CBQ68442.1     12
 SPSC_02487   Sporisorium scitamineum SscI8 CDU23858.1     12
 SPSC_05191   Sporisorium scitamineum SscI8 CDU25357.1     12
 AWJ20_2609   Sugiyamaella lignohabitans CBS 10342 ANB14990.1     12
 AWJ20_757   Sugiyamaella lignohabitans CBS 10342 ANB12501.1     12
 TBLA_0A00910 (Tbla0a00910)   Tetrapisispora blattae CBS 6284 type strain:CBS 6284 CCH57891.1     12
 TPHA_0C01590 (Tpha0c01590)   Tetrapisispora phaffii CBS 4417 CCE62315.1     12
 MYCTH_55232   Thermothelomyces thermophila ATCC 42464 AEO60005.1     12
 THITE_2117189   Thielavia terrestris NRRL 8126 AEO67967.1     12
 TDEL_0H02850 (Tdel0h02850)   Torulaspora delbrueckii type strain:CBS 1146 CCE94144.1     12
 UBRO_00392   Ustilago bromivora UB2112 SAM71140.1     12
 UBRO_05824   Ustilago bromivora UB2112 SAM84544.1     12
 ORF 1 (fragment)   Verticillium dahliae 76 AAX73408.1 Q56NK6   12
 WAN_7517   Wickerhamomyces anomalus NRRL Y-366 AEZ66640.1     12
 WAN_7540   Wickerhamomyces anomalus NRRL Y-366 AEZ66641.1     12
 glycoside hydrolase   Xanthophyllomyces dendrorhous CDZ97258.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CDZ97301.1     12
 Glycoside hydrolase, superfamily   Xanthophyllomyces dendrorhous CED85016.1     12
 YALI0E06149g   Yarrowia lipolytica CLIB122 CAG79198.1 Q6C6U5   12
 YALI0B11418g   Yarrowia lipolytica CLIB122 CAG83006.1 Q6CF03   12
 YALI1_B15151g   Yarrowia lipolytica CLIB89(W29) AOW01550.1     12
 YALI1_E07471g   Yarrowia lipolytica CLIB89(W29) AOW05030.1     12
 BN860_03136g   Zygosaccharomyces bailii CLIB 213 CDF88136.1     12
 BZL39_H01260 (Zpar0h01260_B)   Zygosaccharomyces parabailii ATCC 60483 AQZ14753.1     12
 BZL39_E05940 (Zpar0e05940_A)   Zygosaccharomyces parabailii ATCC 60483 AQZ13254.1     12
 ZYRO0D15092g   Zygosaccharomyces rouxii CBS 732 CAR28152.1     12
 ZT1A5_G10266   Zymoseptoria tritici ST99CH_1A5 SMY28820.1     12
 ZT3D7_G10310   Zymoseptoria tritici ST99CH_3D7 SMQ55155.1     12
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