| Activities in Sub Family | Steryl β-glucosidase (EC 3.2.1.104); β-glucosidase (EC 3.2.1.21); β-glucosylceramidase (EC 3.2.1.45); |
|---|---|
| Mechanism | Retaining e |
| Clan | GH-A |
| 3D Structure Status | ( β / α ) 8 barrel |
| Catalytic Nucleophile/Base | Glu (experimental) |
| Catalytic Proton Donor | Glu (experimental) |
| Note | Once known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189). |
| External resources | CAZypedia; HOMSTRAD; PROSITE; |
| Commercial Enzyme Provider(s) | MEGAZYME; NZYTech; PROZOMIX; |
| Statistics | GenBank accession (1588); Uniprot accession (5); PDB accession (4); 3D entries (2); cryst (0) |
| Eukaryota | ||||||||
| Protein Name | EC# | Reference | Organism | GenBank | Uniprot | PDB/3D | Subf | |
| glucosylceramidase / EGCase related protein 1 (EGCrP1) | 3.2.1.45 | pubmed |
Aspergillus fumigatus | BAL46041.1 | H1AE13 | 8EXD[A,B,C,D] | 12 | |
| β-glucocerebrosidase (EGCrP1;CNAG_00623) | 3.2.1.45 | pubmed |
Cryptococcus neoformans var. grubii H99 | BAL46040.1 AFR92751.1 AFR92751.2 |
H1AE12 | 12 | ||
| steryl β-glucosidase (EGCrP2;CNAG_05607) (vacuolar) | 3.2.1.104 | pubmed |
Cryptococcus neoformans var. grubii H99 | AFR99035.1 | J9W473 | 7LPO[A,B,C,D] 7LPP[A,B,C,D] 7LPQ[A,B,C,D] |
12 | |
| β-glucosylceramidase (EGCrP1;RO3G_04172) | 3.2.1.45 | pubmed |
Rhizopus delemar RA 99-880 | EIE79467.1 | I1BTD7 | 12 | ||
| β-glucosidase (YIR007W;YIB7W) | 3.2.1.21 | pubmed |
Saccharomyces cerevisiae S288c | NP_012272.1 CAA86077.1 CAA86209.1 |
P40566 | 12 | ||
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