Glycoside Hydrolase Family 5 / Subf 11

Activities in Familyendo-β-1,4-glucanase / cellulase (EC 3.2.1.4); endo-β-1,4-xylanase (EC 3.2.1.8); β-glucosidase (EC 3.2.1.21); β-mannosidase (EC 3.2.1.25); β-glucosylceramidase (EC 3.2.1.45); glucan β-1,3-glucosidase (EC 3.2.1.58); licheninase (EC 3.2.1.73); exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74); glucan endo-1,6-β-glucosidase (EC 3.2.1.75); mannan endo-β-1,4-mannosidase (EC 3.2.1.78); cellulose β-1,4-cellobiosidase (EC 3.2.1.91); steryl β-glucosidase (EC 3.2.1.104); endoglycoceramidase (EC 3.2.1.123); chitosanase (EC 3.2.1.132); β-primeverosidase (EC 3.2.1.149); xyloglucan-specific endo-β-1,4-glucanase (EC 3.2.1.151); endo-β-1,6-galactanase (EC 3.2.1.164); hesperidin 6-O-α-L-rhamnosyl-β-glucosidase (EC 3.2.1.168); β-1,3-mannanase (EC 3.2.1.-); arabinoxylan-specific endo-β-1,4-xylanase (EC 3.2.1.-); mannan transglycosylase (EC 2.4.1.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteOnce known as cellulase family A; many members have been assigned to subfamilies as described by Aspeborg et al. (2012) BMC Evol Biol. 12(1):186 (PMID: 22992189).
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (118); Uniprot accession (21);
All (42) Eukaryota (42)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 At1g13130   Arabidopsis thaliana AAU05478.1
AAD31066.1
AEE28973.1
CAW49139.1
CAW49147.1
CAW50877.1
CAW50885.1
CBC20353.1
CBC20368.1
NP_172772.1
Q66GP7
Q9SAE6
  11
 At3g26140   Arabidopsis thaliana BAB02434.1
AEE77125.1
ANM63939.1
ANM63940.1
CAW49140.1
CAW50878.1
CBC20355.1
NP_189245.1
Q9LTM8   11
 At3g26130   Arabidopsis thaliana BAB02432.1
AEE77124.1
ANM65424.1
ANM65425.1
CAW49134.1
CAW50872.1
CBC20341.1
CBD33733.1
NP_189244.1
Q9LTN0   11
 At5g17500   Arabidopsis thaliana CAC01894.1
AED92434.1
CAW49142.1
CAW50880.1
CBC20359.1
NP_197252.1
Q9LF52   11
 At5g16700   Arabidopsis thaliana CAC01834.1
AED92327.1
CAW49141.1
CAW50879.1
CBC20356.1
NP_197172.1
Q9LFE7   11
 GmMAN1 (possible fragment)   Glycine max CAW50873.1
CBC20343.1
    11
 unknown (fragment)   Glycine max ACU18247.1 C6T8U5   11
 predicted protein   Hordeum vulgare subsp. vulgare BAK05121.1     11
 predicted protein   Hordeum vulgare subsp. vulgare BAK00694.1     11
 unknown   Lotus japonicus AFK46453.1     11
 unknown (fragment)   Lotus japonicus AFK48266.1     11
 MGG_06402   Magnaporthe oryzae 70-15 XP_003717168.1
XP_369887.1
    11
 MtrDRAFT_AC149642g20v1   Medicago truncatula ABD32354.1 Q2HTU0   11
 MtrDRAFT_AC141435g4v2 + MtrDRAFT_AC141435g5v2 (fragments)   Medicago truncatula ABO80563.1
ABO80564.1
    11
 unnamed protein product   Oryza sativa CAW50874.1
CBC20345.1
    11
 H0510A06.1   Oryza sativa Indica Group CAH67676.1
CAH66881.1
    11
 H0510A06.2   Oryza sativa Indica Group CAH67677.1
CAH66882.1
    11
 OSIGBa0158F13.11   Oryza sativa Indica Group CAH66880.1     11
 Os04g0480900   Oryza sativa Japonica Group BAF15019.1
BAG98948.1
BAS89738.1
CAD41088.2
CAW49144.1
CAW50875.1
CAW50882.1
CBC20347.1
CBC20363.1
A3AUX3
Q7XUQ6
Q7XUQ7
Q7XUQ8
  11
 Os04g0481000   Oryza sativa Japonica Group CBC20365.1
BAF15020.1
BAS89739.1
CAD41089.2
CAW49145.1
CAW50883.1
Q7XUQ5
Q7XUQ6
  11
 Os04g0481200   Oryza sativa Japonica Group CAD41090.2
BAF15021.1
BAS89740.1
CAW49146.1
CAW50884.1
CBC20366.1
Q7XUQ4
Q7XUQ5
Q7XUQ6
  11
 Os02g0596200   Oryza sativa Japonica Group BAD16839.1
BAD21617.1
BAF09234.1
BAS79555.1
CAW49143.1
CAW50881.1
CBC20360.1
Q6ZI46   11
 WS02773_A13   Picea sitchensis ABR17494.1 B8LPB4   11
 2_5099_01 (fragment)   Pinus radiata AEW08277.1     11
 2_5099_01 (fragment)   Pinus taeda AFG69340.1
AFG69337.1
AFG69338.1
AFG69339.1
    11
 2_5099_01 (fragment)   Pinus taeda AFG69336.1     11
 Pa_7_11010   Podospora anserina S mat+ CAP69143.1
CDP32623.1
B2AXL9   11
 MYCTH_94336   Thermothelomyces thermophila ATCC 42464 AEO57401.1     11
 THITE_2120233   Thielavia terrestris NRRL 8126 AEO69593.1     11
 VIGAN_09149100 (Vigan.09g149100)   Vigna angularis var. angularis BAT97907.1     11
 VIGAN_06158400 (Vigan.06g158400)   Vigna angularis var. angularis BAT90354.1     11
 VIGAN_01093100 (Vigan.01g093100)   Vigna angularis var. angularis BAT73448.1     11
 VIGAN_UM166800 (Vigan.umg166800) (fragment)   Vigna angularis var. angularis BAU03734.1     11
 VIGAN_01135500 (Vigan.01g135500) (fragment)   Vigna angularis var. angularis BAT73817.1     11
 VIGAN_01093300 (Vigan.01g093300) (fragment)   Vigna angularis var. angularis BAT73449.1     11
 unknown (fragment)   Zea mays ACG42458.1     11
 unknown (fragment)   Zea mays ACG45164.1     11
 unknown (ZM_BFc0007C01)   Zea mays B73 ACF79301.1 B4FB08   11
 unknown (ZM_BFb0085A03)   Zea mays B73 ACF80825.1
ACN33507.1
B4FFD2   11
 unknown (ZM_BFc0066N17) (fragment)   Zea mays B73 ACF85134.1 B4FSP1   11
 unknown (ZM_BFc0070G19)   Zea mays B73 ACF85192.1
ACG23910.1
ACN27949.1
ACN28477.1
ACN34624.1
ACN34788.1
CAW50876.1
CBC20350.1
B4FSU9   11
 ORF   Zea nicaraguensis AIZ06017.1     11
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