Glycoside Hydrolase Family 59

Activities in Familyβ-galactosidase (EC 3.2.1.23); galactocerebrosidase (EC 3.2.1.46)
Mechanism Retaining (inferred)
ClanGH-A
3D Structure Status( β / α ) 8 (inferred)
Catalytic Nucleophile/BaseGlu (inferred)
Catalytic Proton DonorGlu (inferred)
External resourcesPRINTS;
Statistics GenBank accession (149); Uniprot accession (33); PDB accession (13); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AFR_29160   Actinoplanes friuliensis DSM 7358 AGZ44093.1    
 L083_3276 (GalC)   Actinoplanes sp. N902-109 AGL16786.1    
 ACPL_6175 (GalC)   Actinoplanes sp. SE50/110 AEV87060.1
SLM02870.1
   
 ACPL_3688   Actinoplanes sp. SE50/110 CAJ81035.1
AEV84583.1
SLM00383.1
Q27GR1  
 B737_3945   Amycolatopsis mediterranei RB AGT84609.1    
 B737_6338   Amycolatopsis mediterranei RB AGT87002.1    
 RAM_20355   Amycolatopsis mediterranei S699 AEK42551.1
AFO77481.1
   
 AMES_6338   Amycolatopsis mediterranei S699 AFO79874.1
AEK45067.1
   
 AMED_3993   Amycolatopsis mediterranei U32 ADJ45770.1 D8HPU8  
 AMED_6431   Amycolatopsis mediterranei U32 ADJ48163.1 D8HYL6  
 SD37_23150   Amycolatopsis orientalis B-37 ANN21966.1    
 Bacsa_1415   Bacteroides salanitronis DSM 18170 ADY35987.1    
 B689b_0529   Bifidobacterium breve 689b AHJ22592.1    
 BIP_14930   Bifidobacterium pseudocatenulatum D2CA CBK72664.1    
 BBSC_2246   Bifidobacterium scardovii JCM 12489 = DSM 13734 BAQ32326.1    
 Caci_3581   Catenulispora acidiphila DSM 44928 ACU72486.1 C7QAI7  
 Caci_4910   Catenulispora acidiphila DSM 44928 ACU73770.1 C7Q334  
 Caci_7107   Catenulispora acidiphila DSM 44928 ACU75937.1 C7Q5G8  
 β-galactosidase (Gal59A;Ccel_1238) (Gal59A) 3.2.1.23 [Clostridium] cellulolyticum H10 ABG76970.1
ACL75594.1
Q0PRN1  
 EUS_13590   [Eubacterium] siraeum 70/3 CBK96504.1 D4JTT5  
 ES1_17580   [Eubacterium] siraeum V10Sc8a CBL34686.1 D4MLQ3  
 YC6258_04161   Gynuella sunshinyii YC6258 AJQ96197.1    
 LBUCD034_0249   Lactobacillus buchneri CD034 AFR99355.1    
 Lbuc_0208   Lactobacillus buchneri NRRL B-30929 AEB72489.1    
 BGL52_00180   Lactobacillus casei LC5 ARY90256.1    
 BGL52_00250   Lactobacillus casei LC5 ARY90269.1    
 PL11_002695   Lactobacillus curieae CCTCC M 2011381 AQW20899.1    
 FAM21731_00775   Lactobacillus parabuchneri FAM21731 APR06982.1    
 CCE29_06885   Lactobacillus rhamnosus 4B15 ART95700.1    
 CCE29_06930   Lactobacillus rhamnosus 4B15 ART95707.1    
 A0F16_12770   Lactobacillus rhamnosus ASCC 290 AMQ04278.1    
 A0F16_12720   Lactobacillus rhamnosus ASCC 290 AMQ04268.1    
 LRHK_57   Lactobacillus rhamnosus ATCC 8530 AER62916.1    
 LRHK_47 (Gal59A)   Lactobacillus rhamnosus ATCC 8530 AER62906.1    
 AWJ15_10640   Lactobacillus rhamnosus BFE5264 AQG73400.1    
 AWJ15_10595   Lactobacillus rhamnosus BFE5264 AQG73392.1    
 N507_1741   Lactobacillus rhamnosus DSM 14870 ASY48915.1    
 N507_1753   Lactobacillus rhamnosus DSM 14870 ASY48927.1    
 LGG_00051 (Gal59A)   Lactobacillus rhamnosus GG CAR85946.1
BAI40578.1
C7T8K3  
 LGG_00061   Lactobacillus rhamnosus GG CAR85956.1
BAI40588.1
C7T8L3  
 LC705_00043   Lactobacillus rhamnosus Lc 705 CAR88882.1 C7TF98  
 LC705_00053   Lactobacillus rhamnosus Lc 705 CAR88892.1 C7TFA8  
 LOCK900_0057   Lactobacillus rhamnosus LOCK900 AGP69917.1    
 LOCK900_0046   Lactobacillus rhamnosus LOCK900 AGP69906.1    
 LOCK908_0046   Lactobacillus rhamnosus LOCK908 AGP72733.1    
 LOCK908_0056   Lactobacillus rhamnosus LOCK908 AGP72743.1    
 BGK71_00255   Lactobacillus rhamnosus LR5 ASX15921.1    
 BGK71_00205   Lactobacillus rhamnosus LR5 ASX15912.1    
 BFC96_12705   Lactobacillus rhamnosus LRB AON64401.1    
 BFC96_12660   Lactobacillus rhamnosus LRB AON64394.1    
 BVH57_00585   Lactobacillus rhamnosus Pen ARD31015.1    
 BVH57_00535   Lactobacillus rhamnosus Pen ARD31006.1    
 B4583_12865   Lactobacillus rhamnosus WQ2 AQY36041.1    
 B4583_12910   Lactobacillus rhamnosus WQ2 AQY36048.1    
 Micau_1959   Micromonospora aurantiaca ATCC 27029 ADL45507.1 D9T230  
 GA0070611_2343   Micromonospora auratinigra DSM 44815 SBT43502.1    
 GA0070623_2455   Micromonospora rifamycinica DSM 44983 SCG56757.1    
 ML5_2065   Micromonospora sp. L5 ADU07591.1 D3C731  
 B0W44_10370 (fragment)   Novibacillus thermophilus SG-1 AQS56112.1    
 B0W44_10375 (fragment)   Novibacillus thermophilus SG-1 AQS56113.1    
 SAMN05444162_1358   Paenibacillaceae bacterium GAS479 SDS38334.1    
 SAMN05444162_4833   Paenibacillaceae bacterium GAS479 SDT53630.1    
 PM3016_3917   Paenibacillus mucilaginosus 3016 AFC30718.1    
 B2K_20410   Paenibacillus mucilaginosus K02 AFH63037.1    
 KNP414_04500   Paenibacillus mucilaginosus KNP414 AEI43030.1    
 Pjdr2_4665   Paenibacillus sp. JDR-2 ACT03279.1 C6D8U9  
 L21SP3_01812   Phycisphaerae bacterium L21-RPul-D3 AQQ09990.1    
 L21SP3_00388   Phycisphaerae bacterium L21-RPul-D3 AQQ08601.1    
 STSP1_02287   Phycisphaerae bacterium ST-PulAB-D4 ARN57861.1    
 STSP1_01101   Phycisphaerae bacterium ST-PulAB-D4 ARN56712.1    
 RBI_I00669   Ruminococcus bicirculans 80/3 CCO04392.1    
 RUM_07020 (probable fragment)   Ruminococcus champanellensis 18P13 = JCM 17042 CBL16905.1 D4LBB0  
 AW14_13450   Siansivirga zeaxanthinifaciens CC-SAMT-1 AJR04973.1    
 Spico_0384   Sphaerochaeta coccoides DSM 17374 AEC01613.1    
 SBI_02313 (fragment)   Streptomyces bingchenggensis BCW-1 ADI05434.1 D7BV55  
 SCAT_5670   Streptomyces cattleya NRRL 8057 = DSM 46488 CCB78358.1    
 SCATT_56700   Streptomyces cattleya NRRL 8057 = DSM 46488 AEW98041.1    
 AVL59_14370   Streptomyces griseochromogenes ATCC 14511 ANP56505.1    
 SHJG_1070   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY86347.1    
 SHJGH_0904   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF60570.1    
 SHL15_8950   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO99876.1    
 SHXM_09505   Streptomyces hygroscopicus XM201 AQW56042.1    
 BFF78_37945   Streptomyces puniciscabiei TW1S1 AOR36068.1    
 BFF78_05120   Streptomyces puniciscabiei TW1S1 AOR30516.1    
 M271_02425   Streptomyces rapamycinicus NRRL 5491 AGP52118.1    
 CGL27_48265   Streptomyces sp. 11-1-2 ASQ99756.1    
 SAMN05444521_7953   Streptomyces sp. 3124.6 SHI58305.1    
 AS200_04755   Streptomyces sp. CdTB01 ALV31442.1    
 A4E84_21535   Streptomyces sp. S10(2016) AMW11854.1    
 SVTN_36325   Streptomyces vietnamensis GIM4.0001 AJF68970.1    
 SAMN05444156_3017   Verrucomicrobiaceae bacterium GAS474 SDU27775.1    
 AXE80_06115   Wenyingzhuangia fucanilytica CZ1127 ANW95879.1    
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