Glycoside Hydrolase Family 58

Activities in Familyendo-N-acetylneuraminidase or endo-sialidase (EC 3.2.1.129)
Mechanism Inverting
3D Structure Status6-fold β-propeller
Catalytic Nucleophile/Basewater activated by carboxylate of substrate
Catalytic Proton DonorGlu
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (207); Uniprot accession (19); PDB accession (7); 3D entries (2); cryst (0)
All (197) Bacteria (157) Viruses (40) Structure (2) Characterized (5)
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ECRS218_0003   Enterobacteria phage CUS-3 ABQ88383.1
CAY90197.1
CAZ00764.1
CAZ00804.1
A5VW57  
 endosialidase (Gp90;End;Endo-N;PK1E) 3.2.1.129 Enterobacteria phage K1 CAA55120.1
CAA85449.2
P49714  
 endosialidase (PK1A) 3.2.1.129 Enterobacteria phage K1A ABP02011.1 A4UUQ0  
 α-2,8-/α-2,9-specific endosialidase (endoN92;PHI92_143) 3.2.1.129 Enterobacteria phage phi92 ATCC 35860-B1 CBY99572.1   4HIZ[A,B,C]
 neuraminidase   Escherichia phage ESCO5 AOT23219.1    
 G_1   Escherichia phage G AB-2017 AQN31758.1    
 endosialidase NF (SiA;EndoNF;PK1F) 3.2.1.129 Escherichia phage K1F CAD44528.2
AAC37340.1
AAZ73001.1
CAJ29390.1
Q04830
Q858B1
1V0E[A,B,C,D,E,F]
1V0F[A,B,C,D,E,F]
3GVJ[A]
3GVK[A,B,C]
3GVL[A]
3JU4[A]
 tailspike 63D sialidase   Escherichia phage K1G ADA82273.1 D2XJ95  
 tailspike 63D sialidase   Escherichia phage K1H ADA82322.1 D2XJE4  
 L_66   Escherichia phage L AB-2017 AQN31891.1    
 ORF   Escherichia phage Mt1B1_P10 QNR52595.1    
 ORF   Escherichia phage Mt1B1_P3 QNJ49132.1    
 neuraminidase   Escherichia phage nepoznato QHR65696.1    
 P_4   Escherichia phage P AB-2017 AQN31942.1    
 phAPEC8_00171   Escherichia phage phAPEC8 AFU62742.1    
 tail fiber protein   Escherichia phage phiv205-1 QGF19902.1    
 tail fiber protein   Escherichia phage PNJ1809-36 QPI13004.1    
 ORF   Escherichia phage vB_EcoM_IME392 AXY86125.1    
 ACG-C91_0053   Escherichia phage vB_EcoP_ACG-C91 vB_EcoP_C91 AFH19879.1    
 B_36   Escherichia phage vB_EcoP_B AQN31620.1    
 C_10   Escherichia phage vB_EcoP_C AQN31649.1    
 D_40   Escherichia phage vB_EcoP_D AQN31738.1    
 F_2   Escherichia phage vB_EcoP_F AQT25396.1    
 K_17   Escherichia phage vB_EcoP_K AQN31909.1    
 KAW1A4500_00056   Escherichia phage vB_EcoP_KAW1A4500 QBQ76762.1    
 neuraminidase   Escherichia phage vB_EcoP_PR_Kaz2018 QFP92956.1    
 R_42   Escherichia phage vB_EcoP_R AQN32042.1    
 KE1_029   Escherichia phage vB_EcoS_fKuEco01 QNO11744.1    
 TE1_028   Escherichia phage vB_EcoS_fTaEco01 QNO11892.1    
 TE3_029   Escherichia phage vB_EcoS_fTaEco03 QNO11966.1    
 GT371_00076   Escherichia phage vB_EcoS_XY1 QIG59267.1    
 endosialidase   Escherichia virus AAPEc6 ANT40789.1    
 K1 endosialidase   Escherichia virus K1-5 AAG59822.1 Q9AZ46  
 Gp47   Escherichia virus K1E CAJ29458.1
AQY55045.1
Q2WC58  
 mutPK1A2_p60   Escherichia virus mutPK1A2 ATS93359.1    
 1127AP1_21   Mannheimia phage vB_MhM_1127AP1 AJA73073.1    
 587AP1_21   Mannheimia phage vB_MhM_587AP1 AJA72945.1    
 endosialidase (endoN63D) 3.2.1.129 Phage #D BAA32990.1 O80102  
 ORF   Phage E CAA03522.1
AAO31362.1
   
 tail fibers protein   Salmonella phage IME207 ANW46772.1    
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