Glycoside Hydrolase Family 56

Activities in Familyhyaluronidase (EC 3.2.1.35); chondroitin hydrolase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 7
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
External resourcesPRINTS;
Statistics GenBank accession (379); Uniprot accession (143); PDB accession (6); 3D entries (3); cryst (0)
All (218) Eukaryota (216) Viruses (2) Structure (3) Characterized (34)
| 1 | 2 | 3 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 hyaluronidase 1 (Hya;Hyal-1;TsHyal-1) (partial) 3.2.1.35 Tityus serrulatus AHF72517.1 P85841  
 Hyal1 (fragment)   Tursiops aduncus ADZ57821.1    
 Hyal1 (fragment)   Tursiops truncatus AEB78444.1    
 PH-20 (fragment)   Varecia variegata ABD94484.1 A4K504  
 hyaluronidase (Vesp ma 2) 3.2.1.35 Vespa magnifica CBY83816.1 P86875  
 hyaluronidase (Ves g 2a)   Vespula germanica CAL59818.1 Q05FZ2  
 Ves g 2b (fragment)   Vespula germanica CAL59819.1 Q05FZ1  
 hyaluronidase b (Hya_B;Ves v 2b)   Vespula vulgaris AAX14718.1
CAI77218.1
Q5D7H4  
 hyaluronidase (Ves v 2 allergen) 3.2.1.35 Vespula vulgaris AAB48073.1
AAR78244.1
ABH87700.1
P49370 2ATM[A]
 fPH-20 protein   Vulpes vulpes AAB86588.1 Q29152  
 hyaluronidase XKH1 3.2.1.35 Xenopus laevis AAL67683.1
AAI69767.1
AAI69795.1
Q8UVT7  
 lysosomal hyaluronidase (Hyal2) 3.2.1.35 Xenopus laevis AAL55823.1 Q8UVY6  
 ORF   Xenopus laevis AAH47252.1 Q801T1  
 hyaluronidase (embryonic) XEH1 3.2.1.35 Xenopus laevis AAD28281.1 Q9W6K5  
 Unknown (protein for MGC:121214)   Xenopus tropicalis AAI35205.1 A4IGQ6  
 Unknown (protein for MGC:184955)   Xenopus tropicalis AAI58240.1 B0BM11  
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