Glycoside Hydrolase Family 56

Activities in Familyhyaluronidase (EC 3.2.1.35); chondroitin hydrolase (EC 3.2.1.-)
Mechanism Retaining
3D Structure Status( β / α ) 7 barrel
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (442); Uniprot accession (63); PDB accession (6); 3D entries (3); cryst (0)
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 hyaluronidase (HYA;Api m 2;Apim2;LOC406146) 3.2.1.35 doi
Apis mellifera AAA27730.1
AAB45920.1
AAR78242.1
ABH87698.1
NP_001011619.1
Q08169 1FCQ[A]
1FCU[A]
1FCV[A]
2J88[A]
 hyaluronidase (Spam1;PH-20;p80;bovHyal) 3.2.1.35 pubmed
Bos taurus AAI10184.1
AAP55713.1
AAV41022.1
Q2YDK3
Q5U7L5
Q7YS45
 
 hyaluronidase (Hyal;BvHyal) (partial) 3.2.1.35 pubmed
Brachypelma vagans AFS33217.1 J9XYC6  
 hyaluronidase / chondroitinase (Hyα-1;T22C8.2) 3.2.1.-
3.2.1.35
pubmed
pubmed
Caenorhabditis elegans Bristol N2 CAA88874.1
BAG48551.1
NP_495830.1
G5ECE8
Q22675
 
 hyaluronidase (Conohyal-Cn1) 3.2.1.35 pubmed
Conus consors IV AFH78528.1 I0CME7  
 hyaluronidase (Hya1;CdtHya1) (fragment) (fragment) 3.2.1.35 pubmed
Crotalus durissus terrificus B3EWP2.1    
 hyaluronidase / endo-β-N-acetyl-hexosaminidase (CsHyal) 3.2.1.35 pubmed
Cupiennius salei CUH74573.1 A0A0S4JYH2  
 hyaluronidase (Dol m 2) 3.2.1.35 pubmed
Dolichovespula maculata AAA68279.1
AAR78243.1
ABH87699.1
CAJ98548.1
P49371  
 hyaluronidase (SPAM1) (sperm) 3.2.1.35 pubmed
Homo sapiens AAH26163.1
AAC16482.1
AAC60607.2
AAQ96882.1
AAX13985.1
AAX13986.1
AAX13987.1
AAX13988.1
AAY03322.1
ABJ38775.1
ACJ13740.1
ACM84481.1
BAF84918.1
CAA59086.1
NP_003108.2
NP_694859.1
P38567
Q5D1J4
Q8TC30
 
 chondroitin sulfate hydrolase / hyaluronidase 3 (HYAL3;LUCA-3;LUCA14.2) 3.2.1.-
3.2.1.35
pubmed
pubmed
Homo sapiens AAC70915.1
AAC02729.1
AAD04257.1
AAH05896.1
AAH12892.1
AAM60775.1
AAM60776.1
AAM60777.1
AAM60778.1
ABA67787.1
BAG36242.1
NP_003540.2
B2R8P5
O43820
O60540
Q8NFK2
Q8NFK3
Q8NFK4
Q96E56
Q9BRW9
 
 chondroitin sulfate hydrolase / hyaluronidase 1 (HYAL1;Hyal-1;LUCA1;LUCA-1) 3.2.1.-
3.2.1.35
pubmed
pubmed
Homo sapiens AAD09137.2
AAB67046.1
AAC02730.1
AAD04190.1
AAD53277.1
AAE60457.1
AAE60459.1
AAH25774.1
AAH35695.1
AAM60770.1
AAM60771.1
AAM60772.1
AAM60773.1
AAM60774.1
ABJ38770.1
ABJ38772.1
ACK03148.1
ALQ33600.1
ALQ33601.1
BAF83505.1
BAG53447.1
CAC60225.1
CAG46731.1
NP_009296.1
NP_149349.2
NP_695013.1
NP_695014.1
NP_695015.1
NP_695016.1
NP_695017.1
NP_695018.1
A0A024R2X3
A0A0S2Z3Q0
A8K451
B3KUI5
Q12794
Q6FH23
2PE4[A]
 chondroitin sulfate hydrolase / hyaluronidase 2 (Hyal2;LUCA2;LUCA-2) 3.2.1.-
3.2.1.35
pubmed
pubmed
Homo sapiens AAH00692.1
AAB67045.1
AAC28656.1
AAC62823.1
ABA82488.1
ACK03149.1
BAG52554.1
BAG54602.1
CAA03924.1
NP_003764.3
NP_149348.2
B3KRZ2
Q12891
 
 chondroitin sulfate hydrolase / hyaluronoglucosaminidase 4 / hyaluronidase 4 (Hyal4;HYAL4;HYAL-4) 3.2.1.- pubmed
Homo sapiens AAC98883.1
AAD43186.1
AAI04789.1
AAI04791.1
ACM81328.1
ACM82678.1
ACV97636.1
BAI49593.1
NP_036401.1
QIJ31491.1
QIJ31492.1
A0A6G7MAH8
A0A6G7MAX3
D0VXG1
Q2M3T9
Q9UL99
 
 hyaluronidase 3.2.1.35 pubmed
Loxosceles intermedia AGH25912.1 R4J7Z9  
 hyaluronidase (Hya1;BmHYA1) (partial) 3.2.1.35 pubmed
Mesobuthus martensii ACY69673.1
AHA36327.1
D1MBU1
P86100
 
 hyaluronidase (Spam1;PH-20;Spam) 3.2.1.35 pubmed
Mus musculus AAA76603.1
AAP49832.1
AAX13989.1
AAX13990.1
BAB24161.1
BAC55070.1
NP_033267.1
P48794
Q5D1J0
 
 hyaluronoglucosaminidase 1 (Hyal1;Hyal-1) 3.2.1.35 pubmed
Mus musculus AAC15949.1
AAH21636.1
AAL17822.1
BAC26206.1
CAP19319.1
CAP19320.1
CAP19321.1
CAP19322.1
NP_032343.2
O70229
Q8CE62
Q8VDK0
Q91ZJ9
 
 hyaluronidase 2 (Hyal2;Hyal-2) 3.2.1.35 pubmed
Mus musculus AAK28482.1
AAH60047.1
AAK28481.1
AAL17823.1
AAO49503.1
BAC39851.1
BAC40583.1
BAE21913.1
CAA03888.1
CAA03889.1
NP_034619.1
O35632
Q3UZE4
Q542F2
Q8C309
 
 chondroitin sulfate hydrolase (Hyal4;mHYAL4) 3.2.1.- pubmed
Mus musculus C57BL/6J BAB29454.1
AAI25403.1
AAI32097.1
BAM45641.1
L0MX76
Q05A56
Q9D660
 
 hyaluronidase 3.2.1.35 pubmed
Pterois antennata BAM66299.1 K7ZPU7  
 hyaluronidase 3.2.1.35 pubmed
Pterois volitans BAM66300.1 K7ZMF5  
 hyaluronidase 2 (Hyal2) 3.2.1.35 pubmed
Rattus norvegicus AAD01980.1
AAH62410.1
AAO49504.1
NP_742037.1
Q80ZC7
Q9Z2Q3
 
 hyaluronidase (HYA1;SfHya1) 3.2.1.35 pubmed
Synanceia horrida AAO74499.1 Q801Z8  
 hyaluronidase 2 (Hyal-2;TsHyal-2) 3.2.1.35 pubmed
Tityus serrulatus AHF72516.1 W0HFN9  
 hyaluronidase 1 (Hya;Hyal-1;TsHyal-1) 3.2.1.35 pubmed
Tityus serrulatus AHF72517.1 P85841  
 hyaluronidase (Vesp ma 2) 3.2.1.35 pubmed
Vespa magnifica CBY83816.1 P86875  
 hyaluronidase (Ves v 2 allergen) 3.2.1.35 pubmed
Vespula vulgaris AAB48073.1
AAR78244.1
ABH87700.1
P49370 2ATM[A]
 hyaluronidase XKH1 3.2.1.35 pubmed
Xenopus laevis AAL67683.1
AAI69767.1
AAI69795.1
B7ZQD4
Q8UVT7
 
 lysosomal hyaluronidase (Hyal2) 3.2.1.35 pubmed
Xenopus laevis AAL55823.1 Q8UVY6  
 hyaluronidase (embryonic) XEH1 3.2.1.35 pubmed
Xenopus laevis AAD28281.1 Q9W6K5  
Top


Last update: 2022-01-05 © Copyright 1998-2022
AFMB - CNRS - Université d'Aix-Marseille