Glycoside Hydrolase Family 50

Known Activities	β-agarase (EC 3.2.1.81).
Mechanism	probably retaining
Clan	GH-A
Catalytic Nucleophile/Base	Glu (inferred)
Catalytic Proton Donor	Glu (inferred)
External resources	CAZypedia;
Statistics	GenBank accession (91); Uniprot accession (55);

Summary

All (83) Archaea (2) Bacteria (81) Characterized (14)

Archaea
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
TSIB_0325		Thermococcus sibiricus MM 739	ACS89391.1	C6A196
Tagg_1112		Thermosphaera aggregans DSM 11486	ADG91381.1	D5U2N1
Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
β-agarase (AgaA34) (peptide fragment)	3.2.1.81	Agarivorans albus YKW-34	P85974.1
agarase		Agarivorans sp. AG17	ACU52709.1	D3GCV0
agarase (Hz1;HZ-a;HZ-b;HZ-c)	3.2.1.81	Agarivorans sp. HZ105	ADY17918.1
neoagarotetraose-producing agarase (Hz2)	3.2.1.81	Agarivorans sp. HZ105	ADY17919.1
β-agarase	3.2.1.81	Agarivorans sp. JA-1	ABK97391.1	A1E2A6
β-agarase (AgaA11)	3.2.1.81	Agarivorans sp. JAMB-A11	BAD99519.1	Q4W8F0
β-agarase (AgaD01)		Agarivorans sp. QM38	ABK51379.1	A0MWB7
β-agarase (AgaD02)	3.2.1.81	Agarivorans sp. QM38	ABM90422.1	A2TGZ5
β-agarase	3.2.1.81	Alteromonas sp. E-1	BAE97587.1	Q14UU1
Avin_19460 (AgaA)		Azotobacter vinelandii DJ ATCC BAA-1303	ACO78156.1	C1DEH1
BXY_48270 (fragment)		Bacteriodes xylanisolvens XB1A	CBK69674.1	D6D6H1
BXY_10640		Bacteriodes xylanisolvens XB1A	CBK66218.1	D6D873
BXY_10650		Bacteriodes xylanisolvens XB1A	CBK66219.1	D6D874
BLJ_1916		Bifidobacterium longum subsp. longum JDM301	ADH01339.1	D6ZWT3
bll4656		Bradyrhizobium japonicum USDA 110	BAC49921.1 NP_771296.1	Q89L92
Caka_0369		Coraliomargarita akajimensis DSM 45221	ADE53394.1	D5EMI8
cce_2986		Cyanothece sp. ATCC 51142	ACB52334.1	B1WW01
DMR_13050		Desulfovibrio magneticus RS-1	BAH74796.1	C4XMK5
Fjoh_2081		Flavobacterium johnsoniae UW101	ABQ05111.1	A5FI56
Glaag_1632		Glaciecola agarilytica 4H-3-7+YE-5	AEE22588.1
Glaag_1634		Glaciecola agarilytica 4H-3-7+YE-5	AEE22590.1
Glaag_2339		Glaciecola agarilytica 4H-3-7+YE-5	AEE23284.1
Glaag_2954		Glaciecola agarilytica 4H-3-7+YE-5	AEE23891.1
Lbys_0351		Leadbetterella byssophila DSM 17132	ADQ16129.1	E4RVE3
Lbys_2130		Leadbetterella byssophila DSM 17132	ADQ17826.1	E4RUD5
Mahau_1328		Mahella australiensis 50-1 BON	AEE96522.1
KNP414_00310		Paenibacillus mucilaginosus KNP414	AEI38935.1
KNP414_02334		Paenibacillus mucilaginosus KNP414	AEI40895.1
KNP414_06971		Paenibacillus mucilaginosus KNP414	AEI45483.1
KNP414_06972		Paenibacillus mucilaginosus KNP414	AEI45484.1
KNP414_00305		Paenibacillus mucilaginosus KNP414	AEI38930.1
KNP414_02457		Paenibacillus mucilaginosus KNP414	AEI41018.1
Patl_1971		Pseudoalteromonas atlantica T6c	ABG40489.1	Q15UE9
Patl_2640		Pseudoalteromonas atlantica T6c	ABG41153.1	Q15SI5
Patl_2642		Pseudoalteromonas atlantica T6c	ABG41155.1	Q15SI3
PLES_42771		Pseudomonas aeruginosa LESB58	CAW29032.1	B7UXE5
PAM18_3999		Pseudomonas aeruginosa M18	AEO76480.1
NCGM2_1907		Pseudomonas aeruginosa NCGM2.S1	BAK88766.1
PA1046		Pseudomonas aeruginosa PAO1	AAG04435.1 NP_249737.1	Q9I4S8
PA14_50830		Pseudomonas aeruginosa UCBPP-PA14	ABJ10210.1	Q02IL2
PSEEN1274		Pseudomonas entomophila L48	CAK14167.1	Q1IDU2
PFL_1280		Pseudomonas fluorescens Pf-5	AAY90565.1	Q4KH74
Pfl_1226		Pseudomonas fluorescens Pf0-1	ABA72969.1	Q3KGY7
PFLU1325		Pseudomonas fluorescens SBW25	CAY47580.1	C3K7J9
Psefu_3340		Pseudomonas fulva 12-X	AEF23302.1
PPUBIRD1_1172		Pseudomonas putida BIRD-1	ADR58854.1	E4R769
Pput_1162		Pseudomonas putida F1	ABQ77323.1	A5VZL3
PputGB1_4289		Pseudomonas putida GB-1	ABZ00178.1	B0KUB2
PP1126		Pseudomonas putida KT2440	AAN66751.1 NP_743287.1	Q88NS8
PPS_4135		Pseudomonas putida S16	AEJ14674.1
PputW619_1147		Pseudomonas putida W619	ACA71652.1	B1J1C1
Psed_5958		Pseudonocardia dioxanivorans CB1190	AEA28080.1
RPE_4620		Rhodopseudomonas palustris BisA53	ABJ08540.1	Q07HP4
RPC_4624		Rhodopseudomonas palustris BisB18	ABD90146.1	Q20XJ0
RPD_2419 (possible fragment)		Rhodopseudomonas palustris BisB5	ABE39649.1	Q137U0
RPA2424		Rhodopseudomonas palustris CGA009	CAE27865.1 NP_947766.1
Rpdx1_3083 (fragment)		Rhodopseudomonas palustris DX-1	ADU44664.1	D2MAK6
RPB_3029 (possible fragment)		Rhodopseudomonas palustris HaA2	ABD07731.1	Q2IVM9
Rpal_2702		Rhodopseudomonas palustris TIE-1	ACF01211.1	B3QH22
exo-β-agarase A (AgaA;Sde_1176) (Aga50A)	3.2.1.81	Saccharophagus degradans 2-40	ABD80438.1	Q21LJ1
exo-β-agarase D (AgaD;Sde_2644) (Aga50D)	3.2.1.81	Saccharophagus degradans 2-40	ABD81904.1	Q21HC5
Acid_0712		Solibacter usitatus Ellin6076	ABJ81713.1	Q02B53
SpiGrapes_1591		Spirochaeta sp. Grapes	AEV29398.1
β-agarase (Sco3487;SCE65.23) (neoagarobiose-producing)	3.2.1.81	Streptomyces coelicolor A3(2)	CAB61811.1 NP_627690.1	Q9RKF0
Sfum_3553		Syntrophobacter fumaroxidans MPOB	ABK19223.1	A0LP71
β-agarase (AguL) (fragment)		uncultured bacterium	AAP70366.1	Q6XE78
β-agarase (AguC;AguI) (fragment)		uncultured bacterium	AAP49314.1 AAP70389.1	Q6XE55 Q6XE55
β-agarase B (AguA;AguE)		uncultured bacterium	AAP49317.1 AAP49347.1	Q6XR79 Q6XR79
β-agarase (AguJ)		uncultured bacterium	AAP70364.1	Q6XR79
β-agarase (AguG) (fragment)		uncultured bacterium	AAP70388.1	Q6XE58
β-agarase (Aga41A)	3.2.1.81	Vibrio sp. CN41	ADM25828.1
VEJY3_09145		Vibrio sp. EJY3	AEX22315.1
VEJY3_09155		Vibrio sp. EJY3	AEX22317.1
VEJY3_09425		Vibrio sp. EJY3	AEX22367.1
VEJY3_09150		Vibrio sp. EJY3	AEX22316.1
β-agarase A (AgaA;0107)	3.2.1.81	Vibrio sp. JT0107	BAA03541.1	P48839
exo-β-agarase B (AgaB)	3.2.1.81	Vibrio sp. JT0107	BAA04744.1	P48840
AgaA		Vibrio sp. LA1	AEB71854.1
β-agarase E (AgaE)		Vibrio sp. PO-303	BAG71428.1	B5MEJ0
β-agarase B (AgaB)	3.2.1.81	Vibrio sp. PO-303	BAG71427.1	B5MEI9
VVA1175		Vibrio vulnificus YJ016	BAC97201.1 NP_937231.1	Q7MD61