Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7868); Uniprot accession (703); PDB accession (11); 3D entries (7); cryst (0)
All (7634) Archaea (38) Bacteria (7595) unclassified (1) Structure (7) Characterized (27)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 76 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 A8O17_18955   Bacillus subtilis subsp. subtilis delta6 ANJ32620.1    
 A8O17_14525   Bacillus subtilis subsp. subtilis delta6 ANJ31800.1    
 A8O17_03790   Bacillus subtilis subsp. subtilis delta6 ANJ29764.1    
 A8O17_04325   Bacillus subtilis subsp. subtilis delta6 ANJ29869.1    
 BEN36_14440   Bacillus subtilis subsp. subtilis IIG-Bs27-47-24 ANY33678.1    
 BEN36_11230   Bacillus subtilis subsp. subtilis IIG-Bs27-47-24 ANY33097.1    
 AS891_20160   Bacillus subtilis subsp. subtilis KCTC 3135 ANX09437.1    
 AS891_03395   Bacillus subtilis subsp. subtilis KCTC 3135 ANX06271.1    
 AS891_07825   Bacillus subtilis subsp. subtilis KCTC 3135 ANX07091.1    
 AS891_19625   Bacillus subtilis subsp. subtilis KCTC 3135 ANX09333.1    
 BEP06_10910   Bacillus subtilis subsp. subtilis PG10 ANY35937.1    
 BEP07_10740   Bacillus subtilis subsp. subtilis PS38 ANY38658.1    
 BHY07_04070   Bacillus subtilis subsp. subtilis QB5412 AOT46984.1    
 BHY07_16405   Bacillus subtilis subsp. subtilis QB5412 AOT49331.1    
 BHY07_04605   Bacillus subtilis subsp. subtilis QB5412 AOT47089.1    
 BHY07_20830   Bacillus subtilis subsp. subtilis QB5412 AOT50149.1    
 BH660_04085   Bacillus subtilis subsp. subtilis QB5413 AOT51231.1    
 BH660_10825   Bacillus subtilis subsp. subtilis QB5413 AOT52417.1    
 BH660_15260   Bacillus subtilis subsp. subtilis QB5413 AOT53186.1    
 BH660_04620   Bacillus subtilis subsp. subtilis QB5413 AOT51324.1    
 S100333_03182   Bacillus subtilis subsp. subtilis SRCM100333 ASB71071.1    
 S100333_04144 (CelF)   Bacillus subtilis subsp. subtilis SRCM100333 ASB72007.1    
 S100333_00808 (MelA)   Bacillus subtilis subsp. subtilis SRCM100333 ASB68722.1    
 S100333_00912 (GlvA)   Bacillus subtilis subsp. subtilis SRCM100333 ASB68826.1    
 S100757_00804 (MelA)   Bacillus subtilis subsp. subtilis SRCM100757 ARW01756.1    
 S100757_00900 (GlvA)   Bacillus subtilis subsp. subtilis SRCM100757 ARW01852.1    
 S100757_03034   Bacillus subtilis subsp. subtilis SRCM100757 ARW03962.1    
 S100757_03925 (CelF)   Bacillus subtilis subsp. subtilis SRCM100757 ARW04827.1    
 S100761_03938 (CelF)   Bacillus subtilis subsp. subtilis SRCM100761 ASB59238.1    
 S100761_00904 (GlvA)   Bacillus subtilis subsp. subtilis SRCM100761 ASB56254.1    
 S100761_00806 (MelA)   Bacillus subtilis subsp. subtilis SRCM100761 ASB56156.1    
 S100761_03045   Bacillus subtilis subsp. subtilis SRCM100761 ASB58371.1    
 S101392_00888 (GlvA)   Bacillus subtilis subsp. subtilis SRCM101392 ASB92382.1    
 S101392_03100   Bacillus subtilis subsp. subtilis SRCM101392 ASB94570.1    
 S101392_00789 (MelA)   Bacillus subtilis subsp. subtilis SRCM101392 ASB92283.1    
 S101392_03978 (CelF)   Bacillus subtilis subsp. subtilis SRCM101392 ASB95422.1    
 S101444_03046   Bacillus subtilis subsp. subtilis SRCM101444 ARV99891.1    
 S101444_03940 (CelF)   Bacillus subtilis subsp. subtilis SRCM101444 ARW00760.1    
 S101444_00805 (MelA)   Bacillus subtilis subsp. subtilis SRCM101444 ARV97674.1    
 S101444_00902 (GlvA)   Bacillus subtilis subsp. subtilis SRCM101444 ARV97771.1    
 6-P-α-glucosidase (GlvA;Glv-1;GlgG;BSU08180) 3.2.1.122 Bacillus subtilis subsp. subtilis str. 168 BAA09103.1
AIY92109.1
AQR80772.1
AQR84985.1
CAB12647.1
NP_388699.1
P54716 1NRH[X]
1U8X[X]
 6-P-β-glucosidase (CelF;CelD;LicH;BSU38560) 3.2.1.86 Bacillus subtilis subsp. subtilis str. 168 CAA90288.1
AIY95172.1
AQR83897.1
AQR88112.1
CAB15882.1
NP_391735.1
P46320  
 α-galactosidase (MelA;BSU30300) 3.2.1.22 Bacillus subtilis subsp. subtilis str. 168 AAC00383.1
AIY94353.1
AQR83056.1
AQR87271.1
CAB15008.1
NP_390908.1
O34645  
 α-galacturonidase (LplD;BSU07130) 3.2.1.67 Bacillus subtilis subsp. subtilis str. 168 CAB12532.1
AAA22577.1
AIY92004.1
AQR80669.1
AQR84882.1
NP_388594.1
P39130 3FEF[A,B,C,D]
 BSUB_00786 (LplD)   Bacillus subtilis subsp. subtilis str. AG1839 AIC43329.1    
 BSUB_03219 (MelA)   Bacillus subtilis subsp. subtilis str. AG1839 AIC45725.1    
 BSUB_04095 (LicH)   Bacillus subtilis subsp. subtilis str. AG1839 AIC46571.1    
 BSUB_00893 (MalA)   Bacillus subtilis subsp. subtilis str. AG1839 AIC43434.1    
 I653_18930   Bacillus subtilis subsp. subtilis str. BAB-1 AGI31018.1    
 I653_14505   Bacillus subtilis subsp. subtilis str. BAB-1 AGI30148.1    
 I653_03600   Bacillus subtilis subsp. subtilis str. BAB-1 AGI27982.1    
 I653_04100   Bacillus subtilis subsp. subtilis str. BAB-1 AGI28082.1    
 A7A1_2071   Bacillus subtilis subsp. subtilis str. BSP1 AGA22689.1    
 A7A1_0600   Bacillus subtilis subsp. subtilis str. BSP1 AGA21218.1    
 A7A1_1646 (fragment)   Bacillus subtilis subsp. subtilis str. BSP1 AGA22264.1    
 A7A1_1757 (fragment)   Bacillus subtilis subsp. subtilis str. BSP1 AGA22375.1    
 BSUA_04095 (LicH)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC42340.1    
 BSUA_03219 (MelA)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC41494.1    
 BSUA_00893 (MalA)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC39202.1    
 BSUA_00786 (LplD)   Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 AIC39097.1    
 Q433_04010   Bacillus subtilis subsp. subtilis str. OH 131.1 AIC97290.1    
 Q433_21260   Bacillus subtilis subsp. subtilis str. OH 131.1 AID00159.1    
 Q433_16430   Bacillus subtilis subsp. subtilis str. OH 131.1 AIC99339.1    
 Q433_04600   Bacillus subtilis subsp. subtilis str. OH 131.1 AIC97381.1    
 I33_0923   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP89915.1    
 I33_3084   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP92025.1    
 I33_0804   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP89800.1    
 I33_4012   Bacillus subtilis subsp. subtilis str. RO-NN-1 AEP92918.1    
 BSSX_0801 (MelA)   Bacillus subtilis SX01705 ASK22718.1    
 BSSX_0906   Bacillus subtilis SX01705 ASK22823.1    
 BSSX_3116 (MelA)   Bacillus subtilis SX01705 ASK25008.1    
 BSSX_4058   Bacillus subtilis SX01705 ASK25922.1    
 A3772_03950   Bacillus subtilis SZMC 6179J AMS46257.1    
 A3772_20705   Bacillus subtilis SZMC 6179J AMS49428.1    
 A3772_04485   Bacillus subtilis SZMC 6179J AMS46361.1    
 A3772_16275   Bacillus subtilis SZMC 6179J AMS48606.1    
 BIS30_04525   Bacillus subtilis T30 AJW84499.1    
 BIS30_09060   Bacillus subtilis T30 AJW85302.1    
 BIS30_14190   Bacillus subtilis T30 AJW86203.1    
 BIS30_14695   Bacillus subtilis T30 AJW86298.1    
 CLD04_20130   Bacillus subtilis TLO3 ASZ63298.1    
 CLD04_04340   Bacillus subtilis TLO3 ASZ60464.1    
 CLD04_04830   Bacillus subtilis TLO3 ASZ60553.1    
 CLD04_15580   Bacillus subtilis TLO3 ASZ62489.1    
 M036_15325   Bacillus subtilis TO-A AII36774.1    
 M036_19750   Bacillus subtilis TO-A AII37563.1    
 M036_04210   Bacillus subtilis TO-A AII34856.1    
 ABU16_4057   Bacillus subtilis TO-A JPC AKN15133.1    
 ABU16_1820   Bacillus subtilis TO-A JPC AKN12896.1    
 ABU16_0730   Bacillus subtilis TO-A JPC AKN11806.1    
 ABA10_04460   Bacillus subtilis UD1022 AKI91265.1    
 ABA10_14870   Bacillus subtilis UD1022 AKI93202.1    
 ABA10_03960   Bacillus subtilis UD1022 AKI91169.1    
 ABA10_19350   Bacillus subtilis UD1022 AKI94015.1    
 BKN48_13935   Bacillus subtilis VV2 AOY06334.1    
 BKN48_08735   Bacillus subtilis VV2 AOY05420.1    
 BKN48_04335   Bacillus subtilis VV2 AOY04608.1    
 BKN48_14455   Bacillus subtilis VV2 AOY06435.1    
 C663_0741 (LplD)   Bacillus subtilis XF-1 AGE62583.1    
 C663_2877 (MelA)   Bacillus subtilis XF-1 AGE64626.1    
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