Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (14800); Uniprot accession (703); PDB accession (13); 3D entries (8); cryst (0)
All (14551) Archaea (40) Bacteria (14510) unclassified (1) Structure (8) Characterized (27)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 146 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 B37_00757 (MelA)   Bacillus licheniformis SCCB 37 ARC72810.1    
 B37_00259 (GlvA)   Bacillus licheniformis SCCB 37 ARC72332.1    
 B14_00388 (Lich_1)   Bacillus licheniformis SCDB 14 ARC63415.1    
 B14_03504 (GlvA)   Bacillus licheniformis SCDB 14 ARC66481.1    
 B14_04018 (Lich_2)   Bacillus licheniformis SCDB 14 ARC66981.1    
 B14_03214 (MelA)   Bacillus licheniformis SCDB 14 ARC66211.1    
 B34_03894 (GlvA)   Bacillus licheniformis SCDB 34 ARC71252.1    
 B34_02728 (Lich_1)   Bacillus licheniformis SCDB 34 ARC70142.1    
 B34_03352 (Lich_2)   Bacillus licheniformis SCDB 34 ARC70724.1    
 B34_04254 (MelA)   Bacillus licheniformis SCDB 34 ARC71592.1    
 BaDB11_02272 (Lich_1)   Bacillus licheniformis SCK B11 ARC60912.1    
 BaDB11_02879 (Lich_2)   Bacillus licheniformis SCK B11 ARC61477.1    
 BaDB11_03393 (GlvA)   Bacillus licheniformis SCK B11 ARC61977.1    
 BaDB11_03688 (MelA)   Bacillus licheniformis SCK B11 ARC62252.1    
 S100141_00622 (MelA)   Bacillus licheniformis SRCM100141 ARW41945.1    
 S100141_04182   Bacillus licheniformis SRCM100141 ARW45434.1    
 S100141_03567 (CelF)   Bacillus licheniformis SRCM100141 ARW44861.1    
 S100141_04723 (GlvA)   Bacillus licheniformis SRCM100141 ARW45961.1    
 S101441_03189   Bacillus licheniformis SRCM101441 ARW32734.1    
 S101441_00863 (MelA)   Bacillus licheniformis SRCM101441 ARW30433.1    
 S101441_04216 (CelF)   Bacillus licheniformis SRCM101441 ARW33735.1    
 S101441_00961 (GlvA)   Bacillus licheniformis SRCM101441 ARW30531.1    
 EQY74_06155   Bacillus licheniformis SRCM103529 QAT52487.1    
 EQY74_04720   Bacillus licheniformis SRCM103529 QAT52230.1    
 EQY74_21875   Bacillus licheniformis SRCM103529 QAT55390.1    
 EQY74_01725   Bacillus licheniformis SRCM103529 QAT51671.1    
 ETA57_21645   Bacillus licheniformis SRCM103583 QAW31024.1    
 ETA57_04535   Bacillus licheniformis SRCM103583 QAW27891.1    
 ETA57_01775   Bacillus licheniformis SRCM103583 QAW27392.1    
 ETA57_06510   Bacillus licheniformis SRCM103583 QAW28242.1    
 ETK49_21010   Bacillus licheniformis SRCM103608 QAW39613.1    
 ETK49_04270   Bacillus licheniformis SRCM103608 QAW36505.1    
 ETK49_01695   Bacillus licheniformis SRCM103608 QAW36027.1    
 ETK49_06190   Bacillus licheniformis SRCM103608 QAW36849.1    
 EQJ69_20590   Bacillus licheniformis SRCM103914 QAS18179.1    
 EQJ69_06245   Bacillus licheniformis SRCM103914 QAS15521.1    
 EQJ69_01740   Bacillus licheniformis SRCM103914 QAS14697.1    
 EQJ69_04745   Bacillus licheniformis SRCM103914 QAS15251.1    
 glycoside hydrolase (Gh4B)   Bacillus licheniformis SVD1 BAL45501.1    
 glycoside hydrolase (Gh4D)   Bacillus licheniformis SVD1 BAL45503.1    
 glycoside hydrolase (Gh4C)   Bacillus licheniformis SVD1 BAL45502.1    
 glycoside hydrolase (Gh4A)   Bacillus licheniformis SVD1 BAL45500.1    
 C7M53_05780   Bacillus licheniformis TAB7 AYC50765.1    
 C7M53_21495   Bacillus licheniformis TAB7 AYC53785.1    
 C7M53_04275   Bacillus licheniformis TAB7 AYC50498.1    
 C7M53_01650   Bacillus licheniformis TAB7 AYC50007.1    
 D9Y32_00465   Bacillus licheniformis TCCC 11148 QDL76074.1    
 D9Y32_01970   Bacillus licheniformis TCCC 11148 QDL76331.1    
 D9Y32_04550   Bacillus licheniformis TCCC 11148 QDL76783.1    
 D9Y32_08015   Bacillus licheniformis TCCC 11148 QDL77376.1    
 MUY_001193 (MelA)   Bacillus licheniformis WX-02 AKQ72325.1    
 MUY_000899 (GlvA)   Bacillus licheniformis WX-02 AKQ72031.1    
 MUY_000307   Bacillus licheniformis WX-02 AKQ71439.1    
 MUY_004235 (LicH)   Bacillus licheniformis WX-02 AKQ75367.1    
 D5E69_21710   Bacillus marisflavi 151-25 QHA38137.1    
 D5E69_11940   Bacillus marisflavi 151-25 QHA36463.1    
 D5E69_07100   Bacillus marisflavi 151-25 QHA35620.1    
 CEQ83_13755   Bacillus megaterium QFY73541.1    
 CEQ83_05095   Bacillus megaterium QFY71913.1    
 CEQ83_03935   Bacillus megaterium QFY71687.1    
 BMD_2737 (MelA)   Bacillus megaterium DSM 319 ADF39579.1 D5DHL9  
 BMD_1020   Bacillus megaterium DSM 319 ADF37881.1 D5DB99  
 BMD_0773 (LicH)   Bacillus megaterium DSM 319 ADF37635.1 D5DAY4  
 α-galactosidase (MelA;BmelA) 3.2.1.22 Bacillus megaterium IAM 13418 AGG11047.1    
 BUW91_05110   Bacillus megaterium JX285 AQU72728.1    
 BUW91_13740   Bacillus megaterium JX285 AQU74292.1    
 BUW91_26775   Bacillus megaterium JX285 AQU76824.1    
 BUW91_03890   Bacillus megaterium JX285 AQU72511.1    
 D0440_12030   Bacillus megaterium Mn1-4 QDZ80129.1    
 D0440_20850   Bacillus megaterium Mn1-4 QDZ81793.1    
 D0440_22030   Bacillus megaterium Mn1-4 QDZ82018.1    
 EQG57_03955   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY23767.1    
 EQG57_05165   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY24001.1    
 EQG57_14460   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY25726.1    
 EQG57_14590   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY25745.1    
 BG04_5240   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI20241.1    
 BG04_3065   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23040.1    
 BG04_3305   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23598.1    
 BG04_5216   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI22531.1    
 OEA_13890   Bacillus megaterium NCT-2 AYE50808.1    
 OEA_23075   Bacillus megaterium NCT-2 AYE52512.1    
 OEA_24330   Bacillus megaterium NCT-2 AYE52748.1    
 D0441_04845   Bacillus megaterium Ni2-3 QDZ83784.1    
 D0441_03585   Bacillus megaterium Ni2-3 QDZ83546.1    
 D0441_14295   Bacillus megaterium Ni2-3 QDZ85556.1    
 D0441_28720   Bacillus megaterium Ni2-3 QDZ88259.1    
 D0441_30090   Bacillus megaterium Ni2-3 QDZ88509.1    
 AS52_01020 (Lich_2)   Bacillus megaterium Q3 AKP75985.1    
 AS52_02862 (MelA)   Bacillus megaterium Q3 AKP77823.1    
 AS52_02811 (Lich_3)   Bacillus megaterium Q3 AKP77772.1    
 AS52_00783 (Lich_1)   Bacillus megaterium Q3 AKP75748.1    
 BMQ_0772 (LicH)   Bacillus megaterium QM B1551 ADE67805.1 D5E0Z9  
 BMQ_1015   Bacillus megaterium QM B1551 ADE68048.1 D5DXW6  
 BMQ_2753 (MelA)   Bacillus megaterium QM B1551 ADE69775.1 D5DUB3  
 C1N54_13715   Bacillus megaterium SGAir0080 QCR27849.1    
 C1N54_05085   Bacillus megaterium SGAir0080 QCR26241.1    
 C1N54_03850   Bacillus megaterium SGAir0080 QCR26008.1    
 CIB87_02345   Bacillus megaterium SR7 AXI27906.1    
 CIB87_01010   Bacillus megaterium SR7 AXI27651.1    
 CIB87_12445   Bacillus megaterium SR7 AXI29781.1    
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