Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (13584); Uniprot accession (703); PDB accession (13); 3D entries (8); cryst (0)
All (13322) Archaea (39) Bacteria (13282) unclassified (1) Structure (8) Characterized (27)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 133 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 glycoside hydrolase (Gh4C)   Bacillus licheniformis SVD1 BAL45502.1    
 glycoside hydrolase (Gh4A)   Bacillus licheniformis SVD1 BAL45500.1    
 C7M53_05780   Bacillus licheniformis TAB7 AYC50765.1    
 C7M53_21495   Bacillus licheniformis TAB7 AYC53785.1    
 C7M53_04275   Bacillus licheniformis TAB7 AYC50498.1    
 C7M53_01650   Bacillus licheniformis TAB7 AYC50007.1    
 D9Y32_00465   Bacillus licheniformis TCCC 11148 QDL76074.1    
 D9Y32_01970   Bacillus licheniformis TCCC 11148 QDL76331.1    
 D9Y32_04550   Bacillus licheniformis TCCC 11148 QDL76783.1    
 D9Y32_08015   Bacillus licheniformis TCCC 11148 QDL77376.1    
 MUY_001193 (MelA)   Bacillus licheniformis WX-02 AKQ72325.1    
 MUY_000899 (GlvA)   Bacillus licheniformis WX-02 AKQ72031.1    
 MUY_000307   Bacillus licheniformis WX-02 AKQ71439.1    
 MUY_004235 (LicH)   Bacillus licheniformis WX-02 AKQ75367.1    
 BMD_2737 (MelA)   Bacillus megaterium DSM 319 ADF39579.1 D5DHL9  
 BMD_1020   Bacillus megaterium DSM 319 ADF37881.1 D5DB99  
 BMD_0773 (LicH)   Bacillus megaterium DSM 319 ADF37635.1 D5DAY4  
 α-galactosidase (MelA;BmelA) 3.2.1.22 Bacillus megaterium IAM 13418 AGG11047.1    
 BUW91_05110   Bacillus megaterium JX285 AQU72728.1    
 BUW91_13740   Bacillus megaterium JX285 AQU74292.1    
 BUW91_26775   Bacillus megaterium JX285 AQU76824.1    
 BUW91_03890   Bacillus megaterium JX285 AQU72511.1    
 D0440_12030   Bacillus megaterium Mn1-4 QDZ80129.1    
 D0440_20850   Bacillus megaterium Mn1-4 QDZ81793.1    
 D0440_22030   Bacillus megaterium Mn1-4 QDZ82018.1    
 EQG57_03955   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY23767.1    
 EQG57_05165   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY24001.1    
 EQG57_14460   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY25726.1    
 EQG57_14590   Bacillus megaterium NBRC 15308 = ATCC 14581 QCY25745.1    
 BG04_5240   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI20241.1    
 BG04_3065   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23040.1    
 BG04_3305   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23598.1    
 BG04_5216   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI22531.1    
 OEA_13890   Bacillus megaterium NCT-2 AYE50808.1    
 OEA_23075   Bacillus megaterium NCT-2 AYE52512.1    
 OEA_24330   Bacillus megaterium NCT-2 AYE52748.1    
 D0441_04845   Bacillus megaterium Ni2-3 QDZ83784.1    
 D0441_03585   Bacillus megaterium Ni2-3 QDZ83546.1    
 D0441_14295   Bacillus megaterium Ni2-3 QDZ85556.1    
 D0441_28720   Bacillus megaterium Ni2-3 QDZ88259.1    
 D0441_30090   Bacillus megaterium Ni2-3 QDZ88509.1    
 AS52_01020 (Lich_2)   Bacillus megaterium Q3 AKP75985.1    
 AS52_02862 (MelA)   Bacillus megaterium Q3 AKP77823.1    
 AS52_02811 (Lich_3)   Bacillus megaterium Q3 AKP77772.1    
 AS52_00783 (Lich_1)   Bacillus megaterium Q3 AKP75748.1    
 BMQ_0772 (LicH)   Bacillus megaterium QM B1551 ADE67805.1 D5E0Z9  
 BMQ_1015   Bacillus megaterium QM B1551 ADE68048.1 D5DXW6  
 BMQ_2753 (MelA)   Bacillus megaterium QM B1551 ADE69775.1 D5DUB3  
 C1N54_13715   Bacillus megaterium SGAir0080 QCR27849.1    
 C1N54_05085   Bacillus megaterium SGAir0080 QCR26241.1    
 C1N54_03850   Bacillus megaterium SGAir0080 QCR26008.1    
 CIB87_02345   Bacillus megaterium SR7 AXI27906.1    
 CIB87_01010   Bacillus megaterium SR7 AXI27651.1    
 CIB87_12445   Bacillus megaterium SR7 AXI29781.1    
 C0569_16875   Bacillus megaterium STB1 AUO12894.1    
 C0569_25250   Bacillus megaterium STB1 AUO14474.1    
 C0569_15600   Bacillus megaterium STB1 AUO12650.1    
 C0569_25150   Bacillus megaterium STB1 AUO14458.1    
 BMWSH_4478 (CelF)   Bacillus megaterium WSH-002 AEN91356.1    
 BMWSH_2447 (MelA)   Bacillus megaterium WSH-002 AEN89329.1    
 BMWSH_4226 (Lich1)   Bacillus megaterium WSH-002 AEN91105.1    
 C2I28_12050   Bacillus megaterium YC4-R4 AWD65711.1    
 C2I28_13210   Bacillus megaterium YC4-R4 AWD65937.1    
 C2I28_21935   Bacillus megaterium YC4-R4 AWD67591.1    
 MLA2C4_26935   Bacillus mobilis ML-A2C4 AYF09126.1    
 ABE28_011570   Bacillus muralis G25-68 AOH54990.1    
 ABE28_013680   Bacillus muralis G25-68 AOH55403.1    
 ABE28_008685   Bacillus muralis G25-68 AOH54426.1    
 DJ92_2260   Bacillus mycoides 219298 AIK36001.1    
 BG05_841   Bacillus mycoides ATCC 6462 AJH21791.1    
 B7492_27935   Bacillus mycoides Gnyt1 ARJ24775.1    
 BcerKBAB4_5001   Bacillus mycoides KBAB4 ABY46147.1 A9VR51  
 E1A90_22895 (CelF)   Bacillus mycoides TH26 QBP93580.1    
 A361_14090   Bacillus oceanisediminis 2691 AND40232.1    
 A361_02420   Bacillus oceanisediminis 2691 AND38045.1    
 BaLi_c28640   Bacillus paralicheniformis ATCC 9945a AGN37212.1    
 BaLi_c12680 (MelA)   Bacillus paralicheniformis ATCC 9945a AGN35637.1    
 BaLi_c03540 (Lich1)   Bacillus paralicheniformis ATCC 9945a AGN34768.1    
 BaLi_c09590 (MalA)   Bacillus paralicheniformis ATCC 9945a AGN35353.1    
 BaLi_c40950 (Lich2)   Bacillus paralicheniformis ATCC 9945a AGN38407.1    
 SC10_B2orf01389   Bacillus paralicheniformis BL-09 AJO17104.1    
 SC10_B2orf01876   Bacillus paralicheniformis BL-09 AJO17460.1    
 SC10_B2orf06167   Bacillus paralicheniformis BL-09 AJO20514.1    
 SC10_B2orf00462   Bacillus paralicheniformis BL-09 AJO16474.1    
 D5285_21535   Bacillus paralicheniformis CBMAI 1303 AYQ18461.1    
 D5285_14395   Bacillus paralicheniformis CBMAI 1303 AYQ17173.1    
 D5285_06335   Bacillus paralicheniformis CBMAI 1303 AYQ15708.1    
 D5285_04830   Bacillus paralicheniformis CBMAI 1303 AYQ15450.1    
 D5285_01820   Bacillus paralicheniformis CBMAI 1303 AYQ14913.1    
 BLMD_20475   Bacillus paralicheniformis MDJK30 ARA87677.1    
 BLMD_01875   Bacillus paralicheniformis MDJK30 ARA84298.1    
 BLMD_04625   Bacillus paralicheniformis MDJK30 ARA84789.1    
 BLMD_06125   Bacillus paralicheniformis MDJK30 ARA85044.1    
 BLMD_14170   Bacillus paralicheniformis MDJK30 ARA86531.1    
 BCPR1_01510 (CelF)   Bacillus paranthracis PR1 QCU08509.1    
 BpOF4_12805   Bacillus pseudofirmus OF4 ADC50612.1 D3FXA1  
 C5695_03460   Bacillus pumilus 145 AVM22942.1    
 C5695_09285   Bacillus pumilus 145 AVM24020.1    
 C5695_19280   Bacillus pumilus 145 AVM25876.1    
 C5Y82_17950   Bacillus pumilus 150a AVI42805.1    
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