Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7868); Uniprot accession (703); PDB accession (11); 3D entries (7); cryst (0)
All (7634) Archaea (38) Bacteria (7595) unclassified (1) Structure (7) Characterized (27)
| 1 | ... | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ... | 76 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BSHJ0_00748 (MelA)   Bacillus subtilis HJ0-6 AOA53341.1    
 AW03_037090 (CelF)   Bacillus subtilis HJ5 AKD37077.1    
 AW03_008140   Bacillus subtilis HJ5 AKD34212.1    
 AW03_007140   Bacillus subtilis HJ5 AKD34114.1    
 AW03_028450   Bacillus subtilis HJ5 AKD36220.1    
 A4A60_04725   Bacillus subtilis HRBS-10TDI13 AOS67015.1    
 A4A60_04225   Bacillus subtilis HRBS-10TDI13 AOS66918.1    
 A4A60_15810   Bacillus subtilis HRBS-10TDI13 AOS69037.1    
 A4A60_20825   Bacillus subtilis HRBS-10TDI13 AOS69940.1    
 BHE96_15110   Bacillus subtilis J-5 APH36837.1    
 BHE96_19460   Bacillus subtilis J-5 APH37620.1    
 BHE96_04155   Bacillus subtilis J-5 APH34821.1    
 O7A_04075   Bacillus subtilis KCTC 1028 AKC46257.1    
 O7A_16400   Bacillus subtilis KCTC 1028 AKC48610.1    
 O7A_04610   Bacillus subtilis KCTC 1028 AKC46362.1    
 O7A_20820   Bacillus subtilis KCTC 1028 AKC49426.1    
 BSR08_00645   Bacillus subtilis KH2 API41133.1    
 BSR08_16970   Bacillus subtilis KH2 API44075.1    
 BSR08_00155   Bacillus subtilis KH2 API41041.1    
 BSR08_11745   Bacillus subtilis KH2 API43137.1    
 BAX60_10120   Bacillus subtilis MJ01 APH67724.1    
 BAX60_20615   Bacillus subtilis MJ01 APH69666.1    
 BAX60_04290   Bacillus subtilis MJ01 APH66708.1    
 BAX60_09605   Bacillus subtilis MJ01 APH67630.1    
 B4U62_04580   Bacillus subtilis NCIB 3610 AQZ89717.1    
 B4U62_04055   Bacillus subtilis NCIB 3610 AQZ89617.1    
 B4U62_20750   Bacillus subtilis NCIB 3610 AQZ92733.1    
 B4U62_16285   Bacillus subtilis NCIB 3610 AQZ91915.1    
 QX56_04075   Bacillus subtilis PS832 AIY96316.1    
 QX56_04610   Bacillus subtilis PS832 AIY96421.1    
 QX56_16400   Bacillus subtilis PS832 AIY98662.1    
 QX56_20825   Bacillus subtilis PS832 AIY99482.1    
 U712_03600   Bacillus subtilis PY79 AHA76669.1    
 U712_04145   Bacillus subtilis PY79 AHA76777.1    
 U712_15040   Bacillus subtilis PY79 AHA78946.1    
 U712_19480   Bacillus subtilis PY79 AHA79824.1    
 B657_08180 (MalA)   Bacillus subtilis QB928 AFQ56736.1    
 B657_07130 (LplD)   Bacillus subtilis QB928 AFQ56636.1    
 B657_38560 (LicH)   Bacillus subtilis QB928 AFQ59709.1    
 B657_30300 (MelA)   Bacillus subtilis QB928 AFQ58872.1    
 OB04_00893 (GlvA)   Bacillus subtilis SG6 AIX06579.1    
 OB04_00796 (LplD)   Bacillus subtilis SG6 AIX06482.1    
 OB04_03006 (MelA)   Bacillus subtilis SG6 AIX08657.1    
 OB04_03880 (LicH)   Bacillus subtilis SG6 AIX09497.1    
 CDA59_15885   Bacillus subtilis SR1 ASC83824.1    
 CDA59_10235   Bacillus subtilis SR1 ASC82828.1    
 CDA59_15365   Bacillus subtilis SR1 ASC83723.1    
 CDA59_05770   Bacillus subtilis SR1 ASC82019.1    
 A1D11_00555   Bacillus subtilis subsp. globigii ATCC 49760 AMR60974.1    
 A1D11_15450   Bacillus subtilis subsp. globigii ATCC 49760 AMR63720.1    
 A1D11_15945   Bacillus subtilis subsp. globigii ATCC 49760 AMR63815.1    
 A1D11_06030   Bacillus subtilis subsp. globigii ATCC 49760 AMR61977.1    
 AN935_19530   Bacillus subtilis subsp. inaquosorum DE111 AMA54364.1    
 AN935_15170   Bacillus subtilis subsp. inaquosorum DE111 AMA53548.1    
 AN935_04245   Bacillus subtilis subsp. inaquosorum DE111 AMA51510.1    
 AN935_03750   Bacillus subtilis subsp. inaquosorum DE111 AMA51418.1    
 BSNT_04412 (MelA)   Bacillus subtilis subsp. natto BEST195 BAI86539.1 D4G0A8  
 BSNT_01360 (MalA)   Bacillus subtilis subsp. natto BEST195 BAI84335.1 D4G6H9  
 BSNT_05900 (LicH)   Bacillus subtilis subsp. natto BEST195 BAI87533.1 D4G352  
 BSNT_01220 (LplD)   Bacillus subtilis subsp. natto BEST195 BAI84236.1 D4G680  
 AWV81_04470   Bacillus subtilis subsp. natto CGMCC 2108 AMK71434.1    
 AWV81_03985   Bacillus subtilis subsp. natto CGMCC 2108 AMK71341.1    
 AWV81_15430   Bacillus subtilis subsp. natto CGMCC 2108 AMK73429.1    
 AWV81_20565   Bacillus subtilis subsp. natto CGMCC 2108 AMK74356.1    
 SD85_03835   Bacillus subtilis subsp. spizizenii NRS 231 AJD35412.1    
 SD85_04340   Bacillus subtilis subsp. spizizenii NRS 231 AJD35510.1    
 SD85_14845   Bacillus subtilis subsp. spizizenii NRS 231 AJD37453.1    
 SD85_19385   Bacillus subtilis subsp. spizizenii NRS 231 AJD38283.1    
 BSUW23_03635 (LplD)   Bacillus subtilis subsp. spizizenii str. W23 ADM36783.1 E0TUW5  
 BSUW23_04145 (MalA)   Bacillus subtilis subsp. spizizenii str. W23 ADM36885.1 E0TVN9  
 BSUW23_14685 (MelA)   Bacillus subtilis subsp. spizizenii str. W23 ADM38974.1 E0TXE8  
 BSUW23_19120 (LicH)   Bacillus subtilis subsp. spizizenii str. W23 ADM39858.1 E0TWS2  
 GYO_3279   Bacillus subtilis subsp. spizizenii TU-B-10 AEP87881.1    
 GYO_1086   Bacillus subtilis subsp. spizizenii TU-B-10 AEP85762.1    
 GYO_4257   Bacillus subtilis subsp. spizizenii TU-B-10 AEP88816.1    
 GYO_0973   Bacillus subtilis subsp. spizizenii TU-B-10 AEP85655.1    
 BFI33_04605   Bacillus subtilis subsp. subtilis 168G AOA10121.1    
 BFI33_16395   Bacillus subtilis subsp. subtilis 168G AOA12362.1    
 BFI33_20820   Bacillus subtilis subsp. subtilis 168G AOA13180.1    
 BFI33_04070   Bacillus subtilis subsp. subtilis 168G AOA10017.1    
 RP72_03960   Bacillus subtilis subsp. subtilis 3NA AJE93383.1    
 RP72_04495   Bacillus subtilis subsp. subtilis 3NA AJE93488.1    
 RP72_16290   Bacillus subtilis subsp. subtilis 3NA AJE95733.1    
 RP72_20715   Bacillus subtilis subsp. subtilis 3NA AJE96550.1    
 BSU6051_07130 (LplD)   Bacillus subtilis subsp. subtilis 6051-HGW AGG60069.1    
 BSU6051_38560 (LicH)   Bacillus subtilis subsp. subtilis 6051-HGW AGG63271.1    
 BSU6051_30300 (MelA)   Bacillus subtilis subsp. subtilis 6051-HGW AGG62434.1    
 BSU6051_08180 (MalA)   Bacillus subtilis subsp. subtilis 6051-HGW AGG60170.1    
 AT706_03750   Bacillus subtilis subsp. subtilis BSD-2 ALS81053.1    
 AT706_19885   Bacillus subtilis subsp. subtilis BSD-2 ALS84039.1    
 AT706_14680   Bacillus subtilis subsp. subtilis BSD-2 ALS83109.1    
 AT706_14180   Bacillus subtilis subsp. subtilis BSD-2 ALS83011.1    
 AWM80_03950   Bacillus subtilis subsp. subtilis CU1050 AMB23131.1    
 AWM80_15275   Bacillus subtilis subsp. subtilis CU1050 AMB25285.1    
 AWM80_19705   Bacillus subtilis subsp. subtilis CU1050 AMB26102.1    
 AWM80_04485   Bacillus subtilis subsp. subtilis CU1050 AMB23236.1    
 KHRBS_17280   Bacillus subtilis subsp. subtilis D12-5 AMR47987.1    
 KHRBS_17800   Bacillus subtilis subsp. subtilis D12-5 AMR48076.1    
 KHRBS_05800   Bacillus subtilis subsp. subtilis D12-5 AMR46074.1    
 KHRBS_01310   Bacillus subtilis subsp. subtilis D12-5 AMR45331.1    
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