Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7868); Uniprot accession (703); PDB accession (11); 3D entries (7); cryst (0)
All (7634) Archaea (38) Bacteria (7595) unclassified (1) Structure (7) Characterized (27)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 76 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 COP00_21000   Bacillus glycinifermentans KBN06P03352 ATH94756.1    
 COP00_07705   Bacillus glycinifermentans KBN06P03352 ATH92519.1    
 AM592_12960   Bacillus gobiensis FJAT-4402 ALC82390.1    
 AM592_17075   Bacillus gobiensis FJAT-4402 ALC83092.1    
 AM592_20925   Bacillus gobiensis FJAT-4402 ALC83709.1    
 BH0183 (LicH)   Bacillus halodurans C-125 BAB03902.1
NP_241049.1
Q9KGC1  
 α-galactosidase (MelA;BH2228) (Mel4A) 3.2.1.22 Bacillus halodurans C-125 BAB05947.1
NP_243094.1
Q9KAQ9  
 BH0912   Bacillus halodurans C-125 BAB04631.1
NP_241778.1
Q9KEE0  
 B4U37_04255   Bacillus horikoshii 20a ART75302.1    
 N288_10570   Bacillus infantis NRRL B-14911 AGX04028.1    
 N288_24430   Bacillus infantis NRRL B-14911 AGX06721.1    
 BleG1_0439   Bacillus lehensis G1 AIC93047.1    
 BleG1_1673   Bacillus lehensis G1 AIC94251.1    
 BleG1_3308   Bacillus lehensis G1 AIC95855.1    
 CPQ91_05805   Bacillus licheniformis ATCC 9789 ATI75372.1    
 CPQ91_04300   Bacillus licheniformis ATCC 9789 ATI75104.1    
 CPQ91_01695   Bacillus licheniformis ATCC 9789 ATI74630.1    
 CPQ91_20700   Bacillus licheniformis ATCC 9789 ATI78121.1    
 BL1202_00929 (GlvA)   Bacillus licheniformis BL1202 AOP13898.1    
 BL1202_01331 (MelA)   Bacillus licheniformis BL1202 AOP14280.1    
 BL1202_04396   Bacillus licheniformis BL1202 AOP17316.1    
 BL1202_00350 (CelF)   Bacillus licheniformis BL1202 AOP13333.1    
 BLi00855 / BL03017 (MalA; GlvA)   Bacillus licheniformis DSM 13 = ATCC 14580 AAU39789.1
AAU22440.1
CAM31744.1
Q65MC5  
 BLi04086 / BL03844 (LicH)   Bacillus licheniformis DSM 13 = ATCC 14580 AAU42899.1
AAU25526.1
CAM31728.1
Q65DG5  
 BLi01143 / BL01356 (MelA)   Bacillus licheniformis DSM 13 = ATCC 14580 AAU40051.1
AAU22704.1
Q65LL3  
 BLi00335 / BL01803   Bacillus licheniformis DSM 13 = ATCC 14580 AAU39293.1
AAU21940.1
Q65NS1  
 AB684_05775   Bacillus licheniformis HRBL-15TDI7 AMR09700.1    
 AB684_04265   Bacillus licheniformis HRBL-15TDI7 AMR09432.1    
 AB684_20370   Bacillus licheniformis HRBL-15TDI7 AMR12411.1    
 AB684_01695   Bacillus licheniformis HRBL-15TDI7 AMR08960.1    
 B37_03684 (Lich_1)   Bacillus licheniformis SCCB 37 ARC75707.1    
 B37_04295 (Lich_2)   Bacillus licheniformis SCCB 37 ARC76276.1    
 B37_00757 (MelA)   Bacillus licheniformis SCCB 37 ARC72810.1    
 B37_00259 (GlvA)   Bacillus licheniformis SCCB 37 ARC72332.1    
 B14_00388 (Lich_1)   Bacillus licheniformis SCDB 14 ARC63415.1    
 B14_03504 (GlvA)   Bacillus licheniformis SCDB 14 ARC66481.1    
 B14_04018 (Lich_2)   Bacillus licheniformis SCDB 14 ARC66981.1    
 B14_03214 (MelA)   Bacillus licheniformis SCDB 14 ARC66211.1    
 B34_03894 (GlvA)   Bacillus licheniformis SCDB 34 ARC71252.1    
 B34_02728 (Lich_1)   Bacillus licheniformis SCDB 34 ARC70142.1    
 B34_03352 (Lich_2)   Bacillus licheniformis SCDB 34 ARC70724.1    
 B34_04254 (MelA)   Bacillus licheniformis SCDB 34 ARC71592.1    
 BaDB11_02272 (Lich_1)   Bacillus licheniformis SCK B11 ARC60912.1    
 BaDB11_02879 (Lich_2)   Bacillus licheniformis SCK B11 ARC61477.1    
 BaDB11_03393 (GlvA)   Bacillus licheniformis SCK B11 ARC61977.1    
 BaDB11_03688 (MelA)   Bacillus licheniformis SCK B11 ARC62252.1    
 S100141_00622 (MelA)   Bacillus licheniformis SRCM100141 ARW41945.1    
 S100141_04182   Bacillus licheniformis SRCM100141 ARW45434.1    
 S100141_03567 (CelF)   Bacillus licheniformis SRCM100141 ARW44861.1    
 S100141_04723 (GlvA)   Bacillus licheniformis SRCM100141 ARW45961.1    
 S101441_03189   Bacillus licheniformis SRCM101441 ARW32734.1    
 S101441_00863 (MelA)   Bacillus licheniformis SRCM101441 ARW30433.1    
 S101441_04216 (CelF)   Bacillus licheniformis SRCM101441 ARW33735.1    
 S101441_00961 (GlvA)   Bacillus licheniformis SRCM101441 ARW30531.1    
 glycoside hydrolase (Gh4B)   Bacillus licheniformis SVD1 BAL45501.1    
 glycoside hydrolase (Gh4D)   Bacillus licheniformis SVD1 BAL45503.1    
 glycoside hydrolase (Gh4C)   Bacillus licheniformis SVD1 BAL45502.1    
 glycoside hydrolase (Gh4A)   Bacillus licheniformis SVD1 BAL45500.1    
 MUY_001193 (MelA)   Bacillus licheniformis WX-02 AKQ72325.1    
 MUY_000899 (GlvA)   Bacillus licheniformis WX-02 AKQ72031.1    
 MUY_000307   Bacillus licheniformis WX-02 AKQ71439.1    
 MUY_004235 (LicH)   Bacillus licheniformis WX-02 AKQ75367.1    
 BMD_2737 (MelA)   Bacillus megaterium DSM 319 ADF39579.1 D5DHL9  
 BMD_1020   Bacillus megaterium DSM 319 ADF37881.1 D5DB99  
 BMD_0773 (LicH)   Bacillus megaterium DSM 319 ADF37635.1 D5DAY4  
 α-galactosidase (MelA;BmelA) 3.2.1.22 Bacillus megaterium IAM 13418 AGG11047.1    
 BUW91_05110   Bacillus megaterium JX285 AQU72728.1    
 BUW91_13740   Bacillus megaterium JX285 AQU74292.1    
 BUW91_26775   Bacillus megaterium JX285 AQU76824.1    
 BUW91_03890   Bacillus megaterium JX285 AQU72511.1    
 BG04_5240   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI20241.1    
 BG04_3065   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23040.1    
 BG04_3305   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI23598.1    
 BG04_5216   Bacillus megaterium NBRC 15308 = ATCC 14581 AJI22531.1    
 AS52_01020 (Lich_2)   Bacillus megaterium Q3 AKP75985.1    
 AS52_02862 (MelA)   Bacillus megaterium Q3 AKP77823.1    
 AS52_02811 (Lich_3)   Bacillus megaterium Q3 AKP77772.1    
 AS52_00783 (Lich_1)   Bacillus megaterium Q3 AKP75748.1    
 BMQ_0772 (LicH)   Bacillus megaterium QM B1551 ADE67805.1 D5E0Z9  
 BMQ_1015   Bacillus megaterium QM B1551 ADE68048.1 D5DXW6  
 BMQ_2753 (MelA)   Bacillus megaterium QM B1551 ADE69775.1 D5DUB3  
 BMWSH_4478 (CelF)   Bacillus megaterium WSH-002 AEN91356.1    
 BMWSH_2447 (MelA)   Bacillus megaterium WSH-002 AEN89329.1    
 BMWSH_4226 (Lich1)   Bacillus megaterium WSH-002 AEN91105.1    
 ABE28_011570   Bacillus muralis G25-68 AOH54990.1    
 ABE28_013680   Bacillus muralis G25-68 AOH55403.1    
 ABE28_008685   Bacillus muralis G25-68 AOH54426.1    
 DJ92_2260   Bacillus mycoides 219298 AIK36001.1    
 BG05_841   Bacillus mycoides ATCC 6462 AJH21791.1    
 B7492_27935   Bacillus mycoides Gnyt1 ARJ24775.1    
 BcerKBAB4_5001   Bacillus mycoides KBAB4 ABY46147.1 A9VR51  
 A361_14090   Bacillus oceanisediminis 2691 AND40232.1    
 A361_02420   Bacillus oceanisediminis 2691 AND38045.1    
 BaLi_c28640   Bacillus paralicheniformis ATCC 9945a AGN37212.1    
 BaLi_c12680 (MelA)   Bacillus paralicheniformis ATCC 9945a AGN35637.1    
 BaLi_c03540 (Lich1)   Bacillus paralicheniformis ATCC 9945a AGN34768.1    
 BaLi_c09590 (MalA)   Bacillus paralicheniformis ATCC 9945a AGN35353.1    
 BaLi_c40950 (Lich2)   Bacillus paralicheniformis ATCC 9945a AGN38407.1    
 SC10_B2orf01389   Bacillus paralicheniformis BL-09 AJO17104.1    
 SC10_B2orf01876   Bacillus paralicheniformis BL-09 AJO17460.1    
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