Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (19155); Uniprot accession (703); PDB accession (15); 3D entries (9); cryst (0)
All (18892) Archaea (56) Bacteria (18834) Eukaryota (1) unclassified (1) Structure (9) Characterized (21)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 189 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 RvVAR0630_40680   Agrobacterium vitis VAR06-30 BCH61444.1    
 RvVAR0630_40730   Agrobacterium vitis VAR06-30 BCH61449.1    
 RvVAT039_35370   Agrobacterium vitis VAT03-9 BCH66321.1    
 RvVAT039_35420   Agrobacterium vitis VAT03-9 BCH66326.1    
 ATC03_05525   Agromyces aureus AR33 ANJ26260.1    
 ET445_16685   Agromyces protaetiae FW100M-8 QAY74729.1    
 ET445_16685   Agromyces protaetiae FW100M-8 QAY74729.1    
 DCE93_10420   Agromyces sp. MF30-A AWB96023.1    
 α-galactosidase (aGly)   Alicyclobacillus acidocaldarius ABI81474.1 A6XNR3  
 Aaci_0797   Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV57840.1 C8WU77  
 GI364_16230   Alicyclobacillus sp. SO9 QQE81359.1    
 VSAL_II1024   Aliivibrio salmonicida LFI1238 CAQ81778.1 B6EST0  
 EIJ81_22685   Aliivibrio salmonicida VS224 AZL87049.1    
 DUT88_22130   Alkalihalobacillus clausii 088AE QNM45387.1    
 DUT88_06420   Alkalihalobacillus clausii 088AE QNM42536.1    
 DUT88_22570   Alkalihalobacillus clausii 088AE QNM45464.1    
 DUT88_01165   Alkalihalobacillus clausii 088AE QNM41607.1    
 DUT88_15030   Alkalihalobacillus clausii 088AE QNM44131.1    
 DUT88_05815   Alkalihalobacillus clausii 088AE QNM42425.1    
 BC8716_17720   Alkalihalobacillus clausii DSM 8716 AST97692.1    
 BC8716_08965   Alkalihalobacillus clausii DSM 8716 AST96071.1    
 BC8716_03135   Alkalihalobacillus clausii DSM 8716 AST95025.1    
 BC8716_04340   Alkalihalobacillus clausii DSM 8716 AST95253.1    
 BC8716_02700   Alkalihalobacillus clausii DSM 8716 AST94948.1    
 BC8716_09570   Alkalihalobacillus clausii DSM 8716 AST96180.1    
 DB29_01385   Alkalihalobacillus clausii ENTPro ALA52213.1    
 DB29_04280   Alkalihalobacillus clausii ENTPro ALA55108.1    
 DB29_01640   Alkalihalobacillus clausii ENTPro ALA52468.1    
 DB29_01277   Alkalihalobacillus clausii ENTPro ALA52105.1    
 DB29_02642   Alkalihalobacillus clausii ENTPro ALA53470.1    
 DB29_02546   Alkalihalobacillus clausii ENTPro ALA53374.1    
 Amet_4185   Alkaliphilus metalliredigens QYMF ABR50266.1 A6TVP8  
 Amet_4194   Alkaliphilus metalliredigens QYMF ABR50274.1 A6TVQ6  
 ORF   Alloactinosynnema sp. L-07 CRK56498.1    
 SAMN04489726_6237   Allokutzneria albata DSM 44149 SDN36162.1    
 SAMN04489726_7557   Allokutzneria albata DSM 44149 SDN64411.1    
 HIMB59_00005490   alpha proteobacterium HIMB59 AFS48749.1    
 A9CBEGH2_15700 (LicH)   Amedibacterium intestinale 9CBEGH2 BBK62630.1    
 AXY_06920 (LicH)   Amphibacillus xylanus NBRC 15112 BAM46824.1    
 AXY_14140 (MelA)   Amphibacillus xylanus NBRC 15112 BAM47546.1    
 A4R43_07395   Amycolatopsis albispora WP1 AXB48336.1    
 A4R43_11475   Amycolatopsis albispora WP1 AXB43091.1    
 AJAP_33835 (CelF)   Amycolatopsis japonica MG417-CF17 AIG79575.1    
 SAMN04489733_4771   Amycolatopsis keratiniphila FH 1893 SDU47714.1    
 BB31_20015   Amycolatopsis lurida NRRL 2430 AJK55543.1    
 B737_1151 (CelF)   Amycolatopsis mediterranei RB AGT81815.1    
 B737_3867 (GalA)   Amycolatopsis mediterranei RB AGT84531.1    
 B737_1336 (CelF)   Amycolatopsis mediterranei RB AGT82000.1    
 RAM_05875   Amycolatopsis mediterranei S699 AEK39667.1
AFO74686.1
   
 RAM_19935   Amycolatopsis mediterranei S699 AEK42473.1
AFO77403.1
   
 RAM_06805   Amycolatopsis mediterranei S699 AEK39853.1
AFO74871.1
   
 AMED_1157 (CelF)   Amycolatopsis mediterranei U32 ADJ42972.1 D8I5B8  
 AMED_1342   Amycolatopsis mediterranei U32 ADJ43156.1 D8I706  
 AMED_3913 (GalA)   Amycolatopsis mediterranei U32 ADJ45692.1 D8HNV0  
 AMETH_3856 (fragment)   Amycolatopsis methanolica 239 AIJ23948.1    
 SD37_35445   Amycolatopsis orientalis B-37 ANN20362.1    
 AORI_1152 (CelF)   Amycolatopsis orientalis HCCB10007 AGM03741.1    
 CU254_16330   Amycolatopsis sp. AA4 ATY11857.1    
 CU254_04200   Amycolatopsis sp. AA4 ATY09754.1    
 BKN51_39840   Amycolatopsis sp. BJA-103 AUI63710.1    
 HUT10_20640   Amycolatopsis sp. Hca4 QKV75913.1    
 HUT10_21605   Amycolatopsis sp. Hca4 QKV76081.1    
 HUT10_06645   Amycolatopsis sp. Hca4 QKV73494.1    
 YIM_28055 (Lich2)   Amycolatopsis sp. YIM 10 QFU90785.1    
 YIM_21270 (Lich1)   Amycolatopsis sp. YIM 10 QFU89433.1    
 Apre_0454   Anaerococcus prevotii DSM 20548 ACV28501.1 C7RG90  
 acsn021_19210   Anaerocolumna cellulosilytica SN021 BCJ94352.1    
 acsn021_01390   Anaerocolumna cellulosilytica SN021 BCJ92570.1    
 Ana3638_02135   Anaerocolumna sp. CBA3638 QHQ59744.1    
 Ana3638_24235   Anaerocolumna sp. CBA3638 QHQ63499.1    
 Ana3638_01210   Anaerocolumna sp. CBA3638 QHQ59586.1    
 Ana3638_17035 (MelA)   Anaerocolumna sp. CBA3638 QHQ62277.1    
 bsdcttw_05430   Anaerocolumna sp. CTTW BCJ97502.1    
 bsdcttw_24170 (MelA)   Anaerocolumna sp. CTTW BCJ99376.1    
 bsdcttw_16570   Anaerocolumna sp. CTTW BCJ98616.1    
 bsdcttw_17470 (Agal1)   Anaerocolumna sp. CTTW BCJ98706.1    
 G4Y79_06580   Anaerolinea sp. rifampicinis QPC84039.1    
 G4Y79_09520   Anaerolinea sp. rifampicinis QPC84595.1    
 G4Y79_02940   Anaerolinea sp. rifampicinis QPC83352.1    
 G4Y79_18455   Anaerolinea sp. rifampicinis QPC81653.1    
 G4Y79_03095 (MelA)   Anaerolinea sp. rifampicinis QPC83382.1    
 ANT_04010   Anaerolinea thermophila UNI-1 BAJ62435.1    
 ANT_08810   Anaerolinea thermophila UNI-1 BAJ62915.1    
 ANT_08820 (MelA)   Anaerolinea thermophila UNI-1 BAJ62916.1    
 ANT_09000   Anaerolinea thermophila UNI-1 BAJ62934.1    
 ANT_11080   Anaerolinea thermophila UNI-1 BAJ63142.1    
 ANT_30140   Anaerolinea thermophila UNI-1 BAJ65040.1    
 BEQ56_11100   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43974.1    
 EYQ97_01335   Anaerostipes caccae DSM 14662 QMW70016.1    
 ANCC_32120 (MalH)   Anaerostipes caccae JCM 13470 BCD37176.1    
 DO83_07995   Anaerostipes hadrus BPB5 AQP39533.1    
 DO83_06745   Anaerostipes hadrus BPB5 AQP39327.1    
 DO83_08000   Anaerostipes hadrus BPB5 AQP39534.1    
 AR1Y2_3310   Anaerostipes rhamnosivorans 1y2 QCP36764.1    
 ISX45_04105   Anoxybacillus caldiproteolyticus U458 QPA32180.1    
 CFX0092_a0397   Ardenticatena Cfx-K CUS02278.1
CUS02289.2
   
 CFX0092_a0540 (MelA)   Ardenticatena Cfx-K CUS02418.1
CUS02429.2
   
 ADJ73_05460   Arsenicicoccus sp. oral taxon 190 F0371 AKT50892.1    
 CVO76_08720   Arthrobacter agilis UMCV2 AUZ87701.1    
 HPK19_17680   Arthrobacter citreus NEB 577 QKE74509.1    
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