Glycoside Hydrolase Family 4

Activities in Family6-P-α-glucosidase (EC 3.2.1.122);
α-glucuronidase (EC 3.2.1.139);
α-glucosidase (EC 3.2.1.20);
β-glucosidase (EC 3.2.1.21);
α-galactosidase (EC 3.2.1.22);
Galacturonan α-1,4-galacturonidase (EC 3.2.1.67);
6-P-β-glucosidase (EC 3.2.1.86);
Mechanism Other a,e
3D Structure StatusRossmann fold
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (28194); Uniprot accession (30); PDB accession (21); 3D entries (10); cryst (0)
| 1 | ... | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | ... | 278 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 QPL86_25955 (CelF)   Bacillus bombysepticus Cuernavaca_S2 WIK95730.1    
 LIT24_25615 (CelF)   Bacillus bombysepticus F12 USL07804.1    
 QP042_28565 (CelF)   Bacillus bombysepticus Mi106 D2 head1 chi WIL47289.1    
 CY96_25090   Bacillus bombysepticus str. Wang AHX21139.1    
 EFK13_15400 (MelA)   Bacillus cabrialesii TE3 UQE78122.1    
 EFK13_04620 (GlvA)   Bacillus cabrialesii TE3 UQE79905.1    
 EFK13_19835 (LicH)   Bacillus cabrialesii TE3 UQE78914.1    
 EFK13_04120 (LplD)   Bacillus cabrialesii TE3 UQE79816.1    
 CWI35_11790   [Bacillus] caldolyticus NEB414 AUI37096.1    
 BCA_5337   Bacillus cereus 03BB102 ACO26783.1
AJG54202.1
   
 AK40_3836   Bacillus cereus 03BB108 AJI12077.1    
 NT98_213   Bacillus cereus 03BB87 AIY76307.1    
 FRY47_25560 (CelF)   Bacillus cereus 09 QEF19604.1    
 FORC085_5142   Bacillus cereus 1000305 QBZ28191.1    
 B5E38_4084   Bacillus cereus 25 ARO61538.1    
 B5E39_0643   Bacillus cereus 29 ARO63160.1    
 B5E40_10065 (CelF)   Bacillus cereus 39 QOW29875.1    
 BG11_4030   Bacillus cereus 3a AJH60657.1    
 DA68_21945   Bacillus cereus A1 ANE88229.1    
 FHP23_025975 (CelF)   Bacillus cereus A22 UDW06202.1    
 FHQ13_012790 (CelF)   Bacillus cereus A24 UDW03239.1    
 BCAH187_A5373   Bacillus cereus AH187 ACJ77841.1    
 BCAH820_5297 (CelF)   Bacillus cereus AH820 ACK90542.1    
 BCE5318 (CelF)   Bacillus cereus ATCC 10987 AAS44218.1
NP_981610.1
   
 BC5209   Bacillus cereus ATCC 14579 AAP12074.1
NP_834873.1
   
 EJ379_26600   Bacillus cereus ATCC 14579 QCX96973.1    
 CelF (fragment)   Bacillus cereus ATCC 14579 CAB66321.1    
 BF35_2972   Bacillus cereus ATCC 4342 AJH76559.1    
 BCB4264_A5328 (CelF)   Bacillus cereus B4264 ACK59337.1    
 B2J90_26670   Bacillus cereus BC-AK ARO20843.1    
 J8Y16_25430 (CelF)   Bacillus cereus BC06 QUW26354.1    
 J8Y17_25705 (CelF)   Bacillus cereus BC07 QUW31500.1    
 J8Y18_25760 (CelF)   Bacillus cereus BC33 QUW36948.1    
 CPZ31_26060   Bacillus cereus BHU1 ATI62277.1    
 CPZ32_07865   Bacillus cereus BHU2 ATI50309.1    
 BACI_c51930 (CelF)   Bacillus cereus biovar anthracis str. CI ADK07741.1    
 CK938_26720   Bacillus cereus CC-1 ASZ19962.1    
 IMY50_25785 (CelF)   Bacillus cereus CF4-51 QWR97781.1    
 WR51_26775   Bacillus cereus CMCC P0011 ANC16378.1    
 WR47_26775   Bacillus cereus CMCC P0021 ANC10562.1    
 D0437_25405   Bacillus cereus Co1-1 QDZ76222.1    
 HPG46_25010 (CelF)   Bacillus cereus CTMA_1571 QKE10010.1    
 BA203_25230   Bacillus cereus D12_2 ASI75370.1    
 AW22_5019   Bacillus cereus D17 AJG58139.1    
 BTZK4901 (CelF)   Bacillus cereus E33L AAU15379.1
AJI28755.1
   
 INQ58_26085 (CelF)   Bacillus cereus EFR-1 QPA44663.1    
 bcf_26050   Bacillus cereus F837/76 AEW58303.1    
 FOC74_19655 (CelF)   Bacillus cereus FDAARGOS_780 QKH75067.1    
 FOC75_23790 (CelF)   Bacillus cereus FDAARGOS_781 QKH68494.1    
 FOC91_11055 (CelF)   Bacillus cereus FDAARGOS_797 QKI12498.1    
 FOC92_14310 (CelF)   Bacillus cereus FDAARGOS_798 QKH13085.1    
 FOC93_23205 (CelF)   Bacillus cereus FDAARGOS_799 QKH08830.1    
 FOC96_06520 (CelF)   Bacillus cereus FDAARGOS_802 QKG99884.1    
 I6G76_26315 (CelF)   Bacillus cereus FDAARGOS_919 QQA21227.1    
 BG03_5435   Bacillus cereus FM1 AJG93528.1    
 FORC21_5066   Bacillus cereus FORC021 AQQ65861.1    
 FORC087_5217   Bacillus cereus FORC087 QDD86506.1    
 FORC60_5294   Bacillus cereus FORC60 AVR35099.1    
 FORC5_4899   Bacillus cereus FORC_005 AKE19436.1    
 FORC13_5143   Bacillus cereus FORC_013 ALZ64204.1    
 FORC24_4962   Bacillus cereus FORC_024 AOM08252.1    
 FORC47_5106   Bacillus cereus FORC_047 ASL67951.1    
 FORC48_5198   Bacillus cereus FORC_048 ASI86274.1    
 FORC086_26415   Bacillus cereus FORC_086 QCT47390.1    
 BCK_09355   Bacillus cereus FRI-35 AFQ09778.1    
 BcrFT9_04165   Bacillus cereus FT9 AIE81671.1    
 AQ16_2809   Bacillus cereus G9241 AJI05750.1    
 BCG9842_B5631 (CelF)   Bacillus cereus G9842 ACK93050.1    
 F3L01_26975 (CelF)   Bacillus cereus H2 QLF04433.1    
 CJ306_27800   Bacillus cereus HBL-AI ASZ68883.1    
 HQJ03_025085 (CelF)   Bacillus cereus HD1.4B UDV82179.1    
 HQG80_025070 (CelF)   Bacillus cereus HD2.4 UDV87723.1    
 WR52_26550   Bacillus cereus HN001 ANC22175.1    
 WHT_07500   Bacillus cereus HT18 BCT37549.1    
 GNE09_04920 (CelF)   Bacillus cereus JHU QGV06259.1    
 BA204_25225   Bacillus cereus K8 ASJ51228.1    
 BA201_26155   Bacillus cereus M13 ASK17265.1    
 BA202_25510   Bacillus cereus M3 ASI80450.1    
 C1T25_15315   Bacillus cereus MBGJa3 AUZ27531.1    
 C1T25_04340   Bacillus cereus MBGJa3 AUZ25536.1    
 C1T25_19875   Bacillus cereus MBGJa3 AUZ28350.1    
 C1T25_04865   Bacillus cereus MBGJa3 AUZ25629.1    
 CSW12_25825   Bacillus cereus MLY1 AUB66221.1    
 BCN_5124   Bacillus cereus NC7401 BAL20917.1    
 ACN91_01865   Bacillus cereus NJ-W ALC50379.1    
 BCQ_5031 (CelF)   Bacillus cereus Q1 ACM15431.1    
 BF33_4616   Bacillus cereus S2-8 AJK37237.1    
 GE376_26730 (CelF)   Bacillus cereus SB1 QFY02695.1    
 C1N66_12085 (CelF)   Bacillus cereus SGAir0260 QHV43821.1    
 C1N82_30045   Bacillus cereus SGAir0263 QHV07240.1    
 C2I25_13195   Bacillus cereus TG1-6 AVP45952.1    
 JTF64_21000 (CelF)   Bacillus cereus VKM B-370 QRY14451.1    
 HLB41_01680 (CelF)   Bacillus cereus WPySW2 QJU32578.1    
 DT426_26170   Bacillus cereus ZB201708 AZV68969.1    
 CG474_020325   Bacillus cytotoxicus CH_1 AWC62782.1    
 CG479_019945   Bacillus cytotoxicus CH_13 AWC46542.1    
 CG480_020765   Bacillus cytotoxicus CH_15 AWC42652.1    
 CG476_020970   Bacillus cytotoxicus CH_2 AWC58761.1    
 CG481_020600   Bacillus cytotoxicus CH_23 AWC38563.1    
 CG482_020760   Bacillus cytotoxicus CH_25 AWC34566.1    
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