Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Statistics GenBank accession (14263); Uniprot accession (703); PDB accession (13); 3D entries (8); cryst (0)
All (14020) Archaea (39) Bacteria (13980) unclassified (1) Structure (8) Characterized (27)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 140 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Atu4665 (MelA)   Agrobacterium fabrum str. C58 AAK88782.2
AAK88782.1
AAL45459.1
NP_355997.1
NP_355997.2
NP_535143.1
Q7CVJ3  
 Arad_9538 (Agal2)   Agrobacterium radiobacter K84 ACM30558.1 B9JKW6  
 Arad_9545 (Agal1)   Agrobacterium radiobacter K84 ACM30563.1 B9JKX1  
 B0909_14205   Agrobacterium rhizogenes K599 AQS63539.1    
 B0909_14180   Agrobacterium rhizogenes K599 AQS63534.1    
 EYD00_22520   Agrobacterium sp. 33MFTa1.1 QBJ16143.1    
 EYD00_22545   Agrobacterium sp. 33MFTa1.1 QBJ16148.1    
 AGROH133_09638   Agrobacterium sp. H13-3 ADY65916.1    
 AGROH133_09618   Agrobacterium sp. H13-3 ADY65911.1    
 BSY240_3746   Agrobacterium sp. RAC06 AOG09386.1    
 At12D1_48050 (MelA)   Agrobacterium tumefaciens 12D1 AYM84687.1    
 At12D1_48000 (MelA)   Agrobacterium tumefaciens 12D1 AYM84682.1    
 At15955_43210 (MelA)   Agrobacterium tumefaciens 15955 AYM19306.1    
 At15955_43160 (MelA)   Agrobacterium tumefaciens 15955 AYM19301.1    
 DC439_23490   Agrobacterium tumefaciens 183 QAB00628.1    
 DC439_23515   Agrobacterium tumefaciens 183 QAB00633.1    
 CG010_024535   Agrobacterium tumefaciens 186 QDY97243.1    
 CG010_024560   Agrobacterium tumefaciens 186 QDY97248.1    
 At1D1108_43850 (MelA)   Agrobacterium tumefaciens 1D1108 AYM14011.1    
 At1D1108_43800 (MelA)   Agrobacterium tumefaciens 1D1108 AYM14006.1    
 At1D1460_44540 (MelA)   Agrobacterium tumefaciens 1D1460 AYM08695.1    
 At1D1460_44490 (MelA)   Agrobacterium tumefaciens 1D1460 AYM08690.1    
 At1D1609_48030 (MelA)   Agrobacterium tumefaciens 1D1609 AVH44844.1    
 At1D1609_47980 (MelA)   Agrobacterium tumefaciens 1D1609 AVH44839.1    
 AtA6_43860 (MelA)   Agrobacterium tumefaciens A6 AYM70602.1    
 AtA6_43910 (MelA)   Agrobacterium tumefaciens A6 AYM70607.1    
 Ach5_43890 (MelA)   Agrobacterium tumefaciens Ach5 AKC10162.1    
 Ach5_43840 (MelA)   Agrobacterium tumefaciens Ach5 AKC10157.1    
 CFBP5499_15805   Agrobacterium tumefaciens CFBP5499 QCL74992.1    
 CFBP5499_15780   Agrobacterium tumefaciens CFBP5499 QCL74987.1    
 CFBP5877_15315   Agrobacterium tumefaciens CFBP5877 QCL80547.1    
 CFBP5877_15340   Agrobacterium tumefaciens CFBP5877 QCL80552.1    
 CFBP6623_23990   Agrobacterium tumefaciens CFBP6623 QCL92175.1    
 CFBP6623_24015   Agrobacterium tumefaciens CFBP6623 QCL92180.1    
 CFBP6624_23795   Agrobacterium tumefaciens CFBP6624 QCM03152.1    
 CFBP6624_23820   Agrobacterium tumefaciens CFBP6624 QCM03157.1    
 CFBP6625_23670   Agrobacterium tumefaciens CFBP6625 QCM13332.1    
 CFBP6625_23695   Agrobacterium tumefaciens CFBP6625 QCM13337.1    
 CFBP6626_22840   Agrobacterium tumefaciens CFBP6626 QCM08108.1    
 CFBP6626_22815   Agrobacterium tumefaciens CFBP6626 QCM08103.1    
 CFBP7129_24435   Agrobacterium tumefaciens CFBP7129 QCL97274.1    
 CFBP7129_24410   Agrobacterium tumefaciens CFBP7129 QCL97269.1    
 X971_4578   Agrobacterium tumefaciens LBA4213 (Ach5) AHK04422.1    
 X971_4573   Agrobacterium tumefaciens LBA4213 (Ach5) AHK04417.1    
 AWN88_02375   Agrobacterium tumefaciens S33 AMD57121.1    
 AWN88_02400   Agrobacterium tumefaciens S33 AMD57126.1    
 Avi_5115 (MelA)   Agrobacterium vitis S4 ACM38294.1 B9K096  
 Avi_5121 (MelA)   Agrobacterium vitis S4 ACM38299.1 B9K0A1  
 ATC03_05525   Agromyces aureus AR33 ANJ26260.1    
 ET445_16685   Agromyces sp. FW100M-8 QAY74729.1    
 ET445_16685   Agromyces sp. FW100M-8 QAY74729.1    
 DCE93_10420   Agromyces sp. MF30-A AWB96023.1    
 α-galactosidase (aGly)   Alicyclobacillus acidocaldarius ABI81474.1 A6XNR3  
 Aaci_0797   Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV57840.1 C8WU77  
 VSAL_II1024   Aliivibrio salmonicida LFI1238 CAQ81778.1 B6EST0  
 EIJ81_22685   Aliivibrio salmonicida VS224 AZL87049.1    
 Amet_4185   Alkaliphilus metalliredigens QYMF ABR50266.1 A6TVP8  
 Amet_4194   Alkaliphilus metalliredigens QYMF ABR50274.1 A6TVQ6  
 ORF   Alloactinosynnema sp. L-07 CRK56498.1    
 SAMN04489726_6237   Allokutzneria albata DSM 44149 SDN36162.1    
 SAMN04489726_7557   Allokutzneria albata DSM 44149 SDN64411.1    
 HIMB59_00005490   alpha proteobacterium HIMB59 AFS48749.1    
 AXY_06920 (LicH)   Amphibacillus xylanus NBRC 15112 BAM46824.1    
 AXY_14140 (MelA)   Amphibacillus xylanus NBRC 15112 BAM47546.1    
 A4R43_07395   Amycolatopsis albispora WP1 AXB48336.1    
 A4R43_11475   Amycolatopsis albispora WP1 AXB43091.1    
 AJAP_33835 (CelF)   Amycolatopsis japonica MG417-CF17 AIG79575.1    
 SAMN04489733_4771   Amycolatopsis keratiniphila FH 1893 SDU47714.1    
 BB31_20015   Amycolatopsis lurida NRRL 2430 AJK55543.1    
 B737_1151 (CelF)   Amycolatopsis mediterranei RB AGT81815.1    
 B737_3867 (GalA)   Amycolatopsis mediterranei RB AGT84531.1    
 B737_1336 (CelF)   Amycolatopsis mediterranei RB AGT82000.1    
 RAM_05875   Amycolatopsis mediterranei S699 AEK39667.1
AFO74686.1
   
 RAM_19935   Amycolatopsis mediterranei S699 AEK42473.1
AFO77403.1
   
 RAM_06805   Amycolatopsis mediterranei S699 AEK39853.1
AFO74871.1
   
 AMED_1157 (CelF)   Amycolatopsis mediterranei U32 ADJ42972.1 D8I5B8  
 AMED_1342   Amycolatopsis mediterranei U32 ADJ43156.1 D8I706  
 AMED_3913 (GalA)   Amycolatopsis mediterranei U32 ADJ45692.1 D8HNV0  
 AMETH_3856 (fragment)   Amycolatopsis methanolica 239 AIJ23948.1    
 SD37_35445   Amycolatopsis orientalis B-37 ANN20362.1    
 AORI_1152 (CelF)   Amycolatopsis orientalis HCCB10007 AGM03741.1    
 CU254_16330   Amycolatopsis sp. AA4 ATY11857.1    
 CU254_04200   Amycolatopsis sp. AA4 ATY09754.1    
 BKN51_39840   Amycolatopsis sp. BJA-103 AUI63710.1    
 YIM_28055 (Lich2)   Amycolatopsis sp. YIM 10 QFU90785.1    
 YIM_21270 (Lich1)   Amycolatopsis sp. YIM 10 QFU89433.1    
 Apre_0454   Anaerococcus prevotii DSM 20548 ACV28501.1 C7RG90  
 ANT_04010   Anaerolinea thermophila UNI-1 BAJ62435.1    
 ANT_08810   Anaerolinea thermophila UNI-1 BAJ62915.1    
 ANT_08820 (MelA)   Anaerolinea thermophila UNI-1 BAJ62916.1    
 ANT_09000   Anaerolinea thermophila UNI-1 BAJ62934.1    
 ANT_11080   Anaerolinea thermophila UNI-1 BAJ63142.1    
 ANT_30140   Anaerolinea thermophila UNI-1 BAJ65040.1    
 BEQ56_11100   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43974.1    
 DO83_07995   Anaerostipes hadrus BPB5 AQP39533.1    
 DO83_06745   Anaerostipes hadrus BPB5 AQP39327.1    
 DO83_08000   Anaerostipes hadrus BPB5 AQP39534.1    
 AR1Y2_3310   Anaerostipes rhamnosivorans 1y2 QCP36764.1    
 FN924_01385   Aquibacillus sp. TKL69 QDP38984.1    
 FN924_02750   Aquibacillus sp. TKL69 QDP39207.1    
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