Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (7442); Uniprot accession (703); PDB accession (11); 3D entries (7); cryst (0)
All (7208) Archaea (38) Bacteria (7169) unclassified (1) Structure (7) Characterized (27)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 72 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AMED_1342   Amycolatopsis mediterranei U32 ADJ43156.1 D8I706  
 AMED_3913 (GalA)   Amycolatopsis mediterranei U32 ADJ45692.1 D8HNV0  
 AMETH_3856 (fragment)   Amycolatopsis methanolica 239 AIJ23948.1    
 SD37_35445   Amycolatopsis orientalis B-37 ANN20362.1    
 AORI_1152 (CelF)   Amycolatopsis orientalis HCCB10007 AGM03741.1    
 Apre_0454   Anaerococcus prevotii DSM 20548 ACV28501.1 C7RG90  
 ANT_04010   Anaerolinea thermophila UNI-1 BAJ62435.1    
 ANT_08810   Anaerolinea thermophila UNI-1 BAJ62915.1    
 ANT_08820 (MelA)   Anaerolinea thermophila UNI-1 BAJ62916.1    
 ANT_09000   Anaerolinea thermophila UNI-1 BAJ62934.1    
 ANT_11080   Anaerolinea thermophila UNI-1 BAJ63142.1    
 ANT_30140   Anaerolinea thermophila UNI-1 BAJ65040.1    
 BEQ56_11100   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43974.1    
 DO83_07995   Anaerostipes hadrus BPB5 AQP39533.1    
 DO83_06745   Anaerostipes hadrus BPB5 AQP39327.1    
 DO83_08000   Anaerostipes hadrus BPB5 AQP39534.1    
 CFX0092_a0397   Ardenticatena Cfx-K CUS02278.1
CUS02289.2
   
 CFX0092_a0540 (MelA)   Ardenticatena Cfx-K CUS02418.1
CUS02429.2
   
 ADJ73_05460   Arsenicicoccus sp. oral taxon 190 F0371 AKT50892.1    
 CGQ24_12155   Arthrobacter sp. 7749 ASN39694.1    
 AUT26_14185   Arthrobacter sp. ATCC 21022 AMB41221.1    
 AL755_20260   Arthrobacter sp. ERGS1:01 ALE07269.1    
 AL755_03805   Arthrobacter sp. ERGS1:01 ALE04814.1    
 Arth_2898   Arthrobacter sp. FB24 ABK04277.1 A0JZ07  
 AHiyo4_35580 (fragment)   Arthrobacter sp. Hiyo4 BAS10136.1    
 AHiyo4_35590 (fragment)   Arthrobacter sp. Hiyo4 BAS10137.1    
 AHiyo8_15470 (fragment)   Arthrobacter sp. Hiyo8 BAS13244.1    
 AHiyo8_15460 (fragment)   Arthrobacter sp. Hiyo8 BAS13243.1    
 AHiyo8_15450 (fragment)   Arthrobacter sp. Hiyo8 BAS13242.1    
 UM93_09305   Arthrobacter sp. IHBB 11108 AJT41657.1    
 BWQ92_16880   Arthrobacter sp. QXT-31 APX03168.1    
 ARUE_c30400 (SimA)   Arthrobacter sp. Rue61a AFR29925.1    
 ASPU41_00500   Arthrobacter sp. U41 AOT02037.1    
 CGK93_16510   Arthrobacter sp. YN ASN21102.1    
 ARZXY2_791 (CelF)   Arthrobacter sp. ZXY-2 AOY70353.1    
 M673_01620   Aureimonas sp. AU20 ALN71389.1    
 M673_01610   Aureimonas sp. AU20 ALN71387.1    
 ABAZ39_24515   Azospirillum brasilense Az39 AIB15058.1    
 AMK58_23570   Azospirillum brasilense Sp 7 ALJ38465.1    
 α-galactosidase (fragment)   Azospirillum brasilense Sp245 ADQ38297.1 E5DGA4  
 AZOBR_p280123 (MelA)   Azospirillum brasilense Sp245 CCD02237.1    
 A6A40_14030   Azospirillum humicireducens SgZ-5 ANC92903.1    
 AZOLI_p50318 (MelA)   Azospirillum lipoferum 4B CBS91312.1    
 AZL_e01400 (MelA)   Azospirillum sp. B510 BAI76485.1 D3P756  
 AL072_30105   Azospirillum thiophilum BV-S ALG75190.1    
 ACG10_20365   Azotobacter chroococcum B3 ASL28414.1    
 Achr_39760 (MelA)   Azotobacter chroococcum NCIMB 8003 AJE23362.1    
 AvCA_51420 (MelA)   Azotobacter vinelandii CA AGK13702.1    
 AvCA6_51420 (MelA)   Azotobacter vinelandii CA6 AGK18264.1    
 Avin_51420 (MelA)   Azotobacter vinelandii DJ ATCC BAA-1303 ACO81220.1 C1DME3  
 A1R12_18105   Bacillus amyloliquefaciens B15 AMR52182.1    
 A1R12_13845   Bacillus amyloliquefaciens B15 AMR51407.1    
 A1R12_04005   Bacillus amyloliquefaciens B15 AMR49562.1    
 U471_08200   Bacillus amyloliquefaciens CC178 AGZ55528.1    
 U471_37230   Bacillus amyloliquefaciens CC178 AGZ58421.1    
 U471_28390   Bacillus amyloliquefaciens CC178 AGZ57537.1    
 BAMF_2811 (MelA)   Bacillus amyloliquefaciens DSM 7 CBI43937.1 E1UND8  
 BAMF_3687 (LicH)   Bacillus amyloliquefaciens DSM 7 CBI44813.1 E1UTJ6  
 BAMF_0787 (MalA)   Bacillus amyloliquefaciens DSM 7 CBI41913.1 E1UNS1  
 KSO_015630   Bacillus amyloliquefaciens IT-45 AGF28613.1    
 KSO_005440   Bacillus amyloliquefaciens IT-45 AGF26585.1    
 KSO_001220   Bacillus amyloliquefaciens IT-45 AGF25747.1    
 KHU1_3310 (LicH)   Bacillus amyloliquefaciens KHG19 AJK67252.1    
 KHU1_2505 (MelA)   Bacillus amyloliquefaciens KHG19 AJK66448.1    
 KHU1_0586   Bacillus amyloliquefaciens KHG19 AJK64555.1    
 SB45_03865   Bacillus amyloliquefaciens L-H15 AJH23160.1    
 SB45_13590   Bacillus amyloliquefaciens L-H15 AJH25058.1    
 SB45_17720   Bacillus amyloliquefaciens L-H15 AJH25845.1    
 XM40_03890   Bacillus amyloliquefaciens L-S60 AKD21403.1    
 XM40_17745   Bacillus amyloliquefaciens L-S60 AKD23961.1    
 XM40_13610   Bacillus amyloliquefaciens L-S60 AKD23213.1    
 U722_04170   Bacillus amyloliquefaciens LFB112 AHC41343.1    
 U722_19040   Bacillus amyloliquefaciens LFB112 AHC44124.1    
 U722_14715   Bacillus amyloliquefaciens LFB112 AHC43316.1    
 LL3_04004 (LicH)   Bacillus amyloliquefaciens LL3 AEB65528.1    
 LL3_00843 (MalA)   Bacillus amyloliquefaciens LL3 AEB62388.1    
 LL3_03104 (MelA)   Bacillus amyloliquefaciens LL3 AEB64635.1    
 BSF20_08020   Bacillus amyloliquefaciens LM2303 APH48334.1    
 BSF20_12205   Bacillus amyloliquefaciens LM2303 APH49100.1    
 BSF20_02830   Bacillus amyloliquefaciens LM2303 APH47406.1    
 AVM03_17770   Bacillus amyloliquefaciens MBE1283 ALV04092.1    
 AVM03_08420   Bacillus amyloliquefaciens MBE1283 ALV02413.1    
 AVM03_12535   Bacillus amyloliquefaciens MBE1283 ALV03166.1    
 WV34_13880   Bacillus amyloliquefaciens MT45 ASF29803.1    
 WV34_18215   Bacillus amyloliquefaciens MT45 ASF30586.1    
 WV34_04555   Bacillus amyloliquefaciens MT45 ASF28084.1    
 BARD7_03500 (CelF)   Bacillus amyloliquefaciens RD7-7 AOC92939.1    
 BARD7_02676 (MelA)   Bacillus amyloliquefaciens RD7-7 AOC92141.1    
 BARD7_00783 (GlvA)   Bacillus amyloliquefaciens RD7-7 AOC90274.1    
 AS588_17900   Bacillus amyloliquefaciens S499 AMP33774.1    
 AS588_01640   Bacillus amyloliquefaciens S499 AMP30759.1    
 AS588_01010   Bacillus amyloliquefaciens S499 AMP30663.1    
 S101267_03989 (CelF)   Bacillus amyloliquefaciens SRCM101267 ARW41047.1    
 S101267_00904 (GlvA)   Bacillus amyloliquefaciens SRCM101267 ARW38013.1    
 S101267_03051 (MelA)   Bacillus amyloliquefaciens SRCM101267 ARW40135.1    
 BAMTA208_19505 (LicH)   Bacillus amyloliquefaciens TA208 AEB26049.1    
 BAMTA208_14810 (MelA)   Bacillus amyloliquefaciens TA208 AEB25123.1    
 BAMTA208_03775 (MalA)   Bacillus amyloliquefaciens TA208 AEB22938.1    
 BAMY6614_08010   Bacillus amyloliquefaciens UMAF6614 AMQ73273.1    
 BAMY6614_02445   Bacillus amyloliquefaciens UMAF6614 AMQ72268.1    
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