Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (9762); Uniprot accession (703); PDB accession (12); 3D entries (8); cryst (0)
All (9515) Archaea (38) Bacteria (9476) unclassified (1) Structure (8) Characterized (27)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 95 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF   Alloactinosynnema sp. L-07 CRK56498.1    
 SAMN04489726_6237   Allokutzneria albata DSM 44149 SDN36162.1    
 SAMN04489726_7557   Allokutzneria albata DSM 44149 SDN64411.1    
 HIMB59_00005490   alpha proteobacterium HIMB59 AFS48749.1    
 AXY_06920 (LicH)   Amphibacillus xylanus NBRC 15112 BAM46824.1    
 AXY_14140 (MelA)   Amphibacillus xylanus NBRC 15112 BAM47546.1    
 AJAP_33835 (CelF)   Amycolatopsis japonica MG417-CF17 AIG79575.1    
 SAMN04489733_4771   Amycolatopsis keratiniphila FH 1893 SDU47714.1    
 BB31_20015   Amycolatopsis lurida NRRL 2430 AJK55543.1    
 B737_1151 (CelF)   Amycolatopsis mediterranei RB AGT81815.1    
 B737_3867 (GalA)   Amycolatopsis mediterranei RB AGT84531.1    
 B737_1336 (CelF)   Amycolatopsis mediterranei RB AGT82000.1    
 RAM_05875   Amycolatopsis mediterranei S699 AEK39667.1
AFO74686.1
   
 RAM_19935   Amycolatopsis mediterranei S699 AEK42473.1
AFO77403.1
   
 RAM_06805   Amycolatopsis mediterranei S699 AEK39853.1
AFO74871.1
   
 AMED_1157 (CelF)   Amycolatopsis mediterranei U32 ADJ42972.1 D8I5B8  
 AMED_1342   Amycolatopsis mediterranei U32 ADJ43156.1 D8I706  
 AMED_3913 (GalA)   Amycolatopsis mediterranei U32 ADJ45692.1 D8HNV0  
 AMETH_3856 (fragment)   Amycolatopsis methanolica 239 AIJ23948.1    
 SD37_35445   Amycolatopsis orientalis B-37 ANN20362.1    
 AORI_1152 (CelF)   Amycolatopsis orientalis HCCB10007 AGM03741.1    
 CU254_16330   Amycolatopsis sp. AA4 ATY11857.1    
 CU254_04200   Amycolatopsis sp. AA4 ATY09754.1    
 BKN51_39840   Amycolatopsis sp. BJA-103 AUI63710.1    
 Apre_0454   Anaerococcus prevotii DSM 20548 ACV28501.1 C7RG90  
 ANT_04010   Anaerolinea thermophila UNI-1 BAJ62435.1    
 ANT_08810   Anaerolinea thermophila UNI-1 BAJ62915.1    
 ANT_08820 (MelA)   Anaerolinea thermophila UNI-1 BAJ62916.1    
 ANT_09000   Anaerolinea thermophila UNI-1 BAJ62934.1    
 ANT_11080   Anaerolinea thermophila UNI-1 BAJ63142.1    
 ANT_30140   Anaerolinea thermophila UNI-1 BAJ65040.1    
 BEQ56_11100   Anaerolineaceae bacterium oral taxon 439 W11661 AOH43974.1    
 DO83_07995   Anaerostipes hadrus BPB5 AQP39533.1    
 DO83_06745   Anaerostipes hadrus BPB5 AQP39327.1    
 DO83_08000   Anaerostipes hadrus BPB5 AQP39534.1    
 CFX0092_a0397   Ardenticatena Cfx-K CUS02278.1
CUS02289.2
   
 CFX0092_a0540 (MelA)   Ardenticatena Cfx-K CUS02418.1
CUS02429.2
   
 ADJ73_05460   Arsenicicoccus sp. oral taxon 190 F0371 AKT50892.1    
 CVO76_08720   Arthrobacter agilis UMCV2 AUZ87701.1    
 AC20117_01125   Arthrobacter crystallopoietes DSM 20117 AUI49617.1    
 CGQ24_12155   Arthrobacter sp. 7749 ASN39694.1    
 AUT26_14185   Arthrobacter sp. ATCC 21022 AMB41221.1    
 AL755_20260   Arthrobacter sp. ERGS1:01 ALE07269.1    
 AL755_03805   Arthrobacter sp. ERGS1:01 ALE04814.1    
 Arth_2898   Arthrobacter sp. FB24 ABK04277.1 A0JZ07  
 AHiyo4_35580 (fragment)   Arthrobacter sp. Hiyo4 BAS10136.1    
 AHiyo4_35590 (fragment)   Arthrobacter sp. Hiyo4 BAS10137.1    
 AHiyo8_15470 (fragment)   Arthrobacter sp. Hiyo8 BAS13244.1    
 AHiyo8_15460 (fragment)   Arthrobacter sp. Hiyo8 BAS13243.1    
 AHiyo8_15450 (fragment)   Arthrobacter sp. Hiyo8 BAS13242.1    
 UM93_09305   Arthrobacter sp. IHBB 11108 AJT41657.1    
 C3B78_13900   Arthrobacter sp. PGP41 AUZ35436.1    
 BWQ92_16880   Arthrobacter sp. QXT-31 APX03168.1    
 ARUE_c30400 (SimA)   Arthrobacter sp. Rue61a AFR29925.1    
 ASPU41_00500   Arthrobacter sp. U41 AOT02037.1    
 CGK93_16510   Arthrobacter sp. YN ASN21102.1    
 ARZXY2_791 (CelF)   Arthrobacter sp. ZXY-2 AOY70353.1    
 M673_01620   Aureimonas sp. AU20 ALN71389.1    
 M673_01610   Aureimonas sp. AU20 ALN71387.1    
 ABAZ39_24515   Azospirillum brasilense Az39 AIB15058.1    
 AMK58_23570   Azospirillum brasilense Sp 7 ALJ38465.1    
 α-galactosidase (fragment)   Azospirillum brasilense Sp245 ADQ38297.1 E5DGA4  
 AZOBR_p280123 (MelA)   Azospirillum brasilense Sp245 CCD02237.1
AWJ94030.1
   
 A6A40_14030   Azospirillum humicireducens SgZ-5 ANC92903.1    
 AZOLI_p50318 (MelA)   Azospirillum lipoferum 4B CBS91312.1    
 AZL_e01400 (MelA)   Azospirillum sp. B510 BAI76485.1 D3P756  
 DEW08_29265   Azospirillum sp. CFH 70021 AWK90076.1    
 DM194_24835   Azospirillum sp. M2T2B2 AWU97534.1    
 TSH58p_00570   Azospirillum sp. TSH58 AWJ82076.1    
 AL072_30105   Azospirillum thiophilum BV-S ALG75190.1    
 ACG10_20365   Azotobacter chroococcum B3 ASL28414.1    
 Achr_39760 (MelA)   Azotobacter chroococcum NCIMB 8003 AJE23362.1    
 AvCA_51420 (MelA)   Azotobacter vinelandii CA AGK13702.1    
 AvCA6_51420 (MelA)   Azotobacter vinelandii CA6 AGK18264.1    
 Avin_51420 (MelA)   Azotobacter vinelandii DJ ATCC BAA-1303 ACO81220.1 C1DME3  
 CSE15_03630   Bacillus altitudinis P-10 ATP93104.1    
 CSE15_18525   Bacillus altitudinis P-10 ATP95826.1    
 CSE15_09225   Bacillus altitudinis P-10 ATP94125.1    
 CFN77_09470   Bacillus altitudinis SGAir0031 ATH72423.1    
 CFN77_18500   Bacillus altitudinis SGAir0031 ATH74126.1    
 CFN77_03520   Bacillus altitudinis SGAir0031 ATH71307.1    
 BAALB65_18945   Bacillus amyloliquefaciens ALB65 AWM45991.1    
 BAALB65_04555   Bacillus amyloliquefaciens ALB65 AWM43352.1    
 BAALB65_14615   Bacillus amyloliquefaciens ALB65 AWM45206.1    
 DDT09_14465   Bacillus amyloliquefaciens ALB69 AWM49000.1    
 DDT09_18810   Bacillus amyloliquefaciens ALB69 AWM49783.1    
 DDT09_04140   Bacillus amyloliquefaciens ALB69 AWM47091.1    
 DDT10_04135   Bacillus amyloliquefaciens ALB79 AWM50917.1    
 DDT10_18425   Bacillus amyloliquefaciens ALB79 AWM53533.1    
 DDT10_14025   Bacillus amyloliquefaciens ALB79 AWM52744.1    
 A1R12_18105   Bacillus amyloliquefaciens B15 AMR52182.1    
 A1R12_13845   Bacillus amyloliquefaciens B15 AMR51407.1    
 A1R12_04005   Bacillus amyloliquefaciens B15 AMR49562.1    
 U471_08200   Bacillus amyloliquefaciens CC178 AGZ55528.1    
 U471_37230   Bacillus amyloliquefaciens CC178 AGZ58421.1    
 U471_28390   Bacillus amyloliquefaciens CC178 AGZ57537.1    
 BAMF_2811 (MelA)   Bacillus amyloliquefaciens DSM 7 CBI43937.1 E1UND8  
 BAMF_3687 (LicH)   Bacillus amyloliquefaciens DSM 7 CBI44813.1 E1UTJ6  
 BAMF_0787 (MalA)   Bacillus amyloliquefaciens DSM 7 CBI41913.1 E1UNS1  
 KSO_015630   Bacillus amyloliquefaciens IT-45 AGF28613.1    
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