Glycoside Hydrolase Family 4

Activities in Familymaltose-6-phosphate glucosidase (EC 3.2.1.122); α-glucosidase (EC 3.2.1.20); α-galactosidase (EC 3.2.1.22); 6-phospho-β-glucosidase (EC 3.2.1.86); α-glucuronidase (EC 3.2.1.139); α-galacturonase (EC 3.2.1.67); palatinase (EC 3.2.1.-)
Mechanism Retaining
Catalytic Nucleophile/BaseNot applicable
Catalytic Proton DonorNot known
NoteThe enzymes in this family display an unusual mechanism involving NAD+.
External resourcesCAZypedia; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (9957); Uniprot accession (703); PDB accession (13); 3D entries (8); cryst (0)
All (9709) Archaea (38) Bacteria (9670) unclassified (1) Structure (8) Characterized (27)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 97 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BN85303790   Acholeplasma brassicae O502 CCV65400.1    
 NCTC10116_00265 (ChbF)   Acholeplasma laidlawii NCTC10116 SQH56488.1    
 ACL_0264   Acholeplasma laidlawii PG-8A ABX80889.1 A9NEV9  
 Aocu_11970   Acholeplasma oculi CDR31270.1    
 PACID_07420   Acidipropionibacterium acidipropionici ATCC 4875 AFV88580.1    
 AXH35_13495   Acidipropionibacterium acidipropionici ATCC 55737 AMS06306.1    
 ASQ49_01095   Acidipropionibacterium acidipropionici CGMCC 1.2230 ALN14082.1    
 A8L58_14945   Acidipropionibacterium acidipropionici F3E8 AOZ47761.1    
 BWX38_13860   Acidipropionibacterium acidipropionici WSH1105 APZ10154.1    
 JS278_02577 (LicH)   Acidipropionibacterium sp. JS278 AXE39715.1    
 LuPra_05374 (MelA)   Acidobacteria bacterium DSM 100886 AMY12102.1    
 BH719_04855   Actinomyces hongkongensis HKU8 AOS47272.1    
 AXF14_09395   Actinomyces radicidentis CCUG 36733 AMD87761.1    
 SAMN04489714_2084   Actinomyces radingae DSM 9169 SDU08777.1    
 SAMN04489716_0905   Actinoplanes derwentensis DSM 43941 SDS49319.1    
 AFR_41250   Actinoplanes friuliensis DSM 7358 AGZ46504.1    
 AFR_22550   Actinoplanes friuliensis DSM 7358 AGZ42780.1    
 AMIS_55320   Actinoplanes missouriensis 431 BAL90752.1    
 L083_4539   Actinoplanes sp. N902-109 AGL18049.1    
 ACWT_5272   Actinoplanes sp. SE50 ATO84687.1    
 ACWT_2033   Actinoplanes sp. SE50 ATO81448.1    
 ACPL_2155   Actinoplanes sp. SE50/110 AEV83052.1
SLL98855.1
   
 ACPL_5403 (BglY)   Actinoplanes sp. SE50/110 AEV86290.1
SLM02097.1
   
 SAMN04489717_1061   Actinopolymorpha singaporensis DSM 22024 SDR92906.1    
 SAMN04489717_4130   Actinopolymorpha singaporensis DSM 22024 SDS85950.1    
 SAMN04489717_4574   Actinopolymorpha singaporensis DSM 22024 SDS97978.1    
 SAMN04489717_2570   Actinopolymorpha singaporensis DSM 22024 SDS39866.1    
 Amir_1458   Actinosynnema mirum DSM 43827 ACU35409.1 C6WAE2  
 CNX65_07235   Actinosynnema pretiosum X47 ATE53105.1    
 ADH66_12280   Acutalibacter muris KB18 ASB41366.1    
 AP3564_08650   Aeribacillus pallidus KCTC3564 ASS90290.1    
 AP3564_01900   Aeribacillus pallidus KCTC3564 ASS89188.1    
 AWM74_01530   Aerococcus urinaeequi CCUG28094 AMB96994.1    
 AWM74_04280   Aerococcus urinaeequi CCUG28094 AMB97503.1    
 AWM74_03935   Aerococcus urinaeequi CCUG28094 AMB97442.1    
 APT62_00760   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ87068.1    
 APT62_00365   Aerococcus urinaeequi USDA-ARS-USMARC-56713 ALZ86998.1    
 AWM76_10250   Aerococcus viridans CCUG4311 AMC01894.1    
 AWM76_09830   Aerococcus viridans CCUG4311 AMC01822.1    
 BOQ57_00415   Aeromonas aquatica MX16A APJ13453.1    
 CK627_04320   Aeromonas dhakensis KN-Mc-6U21 ASX10051.1    
 VU14_21910   Aeromonas hydrophila AH10 AKA19392.1    
 TK34_21640   Aeromonas hydrophila AHNIH1 ANT69818.1    
 RY45_00850   Aeromonas hydrophila AL06-06 AJQ52704.1    
 V428_00660   Aeromonas hydrophila AL09-71 AHX30647.1    
 AhyD4_22545   Aeromonas hydrophila D4 ALZ82262.1    
 A9258_21680   Aeromonas hydrophila GYK1 ANS02129.1    
 V469_22660   Aeromonas hydrophila J-1 AJE38499.1    
 AS145_22715   Aeromonas hydrophila JBN2301 ALQ65585.1    
 C7K70_23040   Aeromonas hydrophila KN-Mc-1R2 AVP86684.1    
 AHML_00605   Aeromonas hydrophila ML09-119 AGM41906.1    
 U876_23305   Aeromonas hydrophila NJ-35 AKJ36795.1    
 V429_00660   Aeromonas hydrophila pc104A AHX67443.1    
 AHA_0115   Aeromonas hydrophila subsp. hydrophila ATCC 7966 ABK39393.1 A0KEI7  
 C1A23_24885   Aeromonas hydrophila subsp. hydrophila WCHAH045096 AWA08576.1    
 AI20_18950   Aeromonas hydrophila YL17 AHV37174.1    
 C7N77_07035   Aeromonas rivipollensis KN-Mc-11N1 AVP92969.1    
 CHQ57_21885   Aeromonas salmonicida A527 ATU99792.1    
 CE456_23795   Aeromonas salmonicida S121 ASI25200.1    
 CE463_23790   Aeromonas salmonicida S44 ASI29519.1    
 CE462_22740   Aeromonas salmonicida S68 ASI33650.1    
 BHG40_04545   Aeromonas salmonicida subsp. masoucida RFAS1 ATD37299.1    
 Asalp_44420 (AglB)   Aeromonas salmonicida subsp. pectinolytica 34mel ATP11505.1    
 ASA_4277   Aeromonas salmonicida subsp. salmonicida A449 ABO92201.1 A4STH9  
 C2U40_22375   Aeromonas sp. ASNIH4 AUZ77311.1    
 CK910_02915   Aeromonas sp. CA23 ATL97560.1    
 CK910_05105   Aeromonas sp. CA23 ATL97939.1    
 CK911_10355   Aeromonas sp. CU5 ATL93170.1    
 CK911_11295   Aeromonas sp. CU5 ATL93337.1    
 O23A_p3722   Aeromonas sp. O23A ARW84461.1    
 WM43_12150   Aeromonas veronii AVNIH1 ANB53358.1    
 B565_2906   Aeromonas veronii B565 AEB50941.1    
 B565_3952   Aeromonas veronii B565 AEB51987.1    
 A6033_18110   Aeromonas veronii CB51 ANB70208.1    
 A6033_03915   Aeromonas veronii CB51 ANB67877.1    
 Atu4660 (MelA)   Agrobacterium fabrum str. C58 AAL45454.1
AAK88787.1
AAK88787.2
NP_356002.1
NP_535138.1
Q7CVI8  
 Atu4665 (MelA)   Agrobacterium fabrum str. C58 AAK88782.2
AAK88782.1
AAL45459.1
NP_355997.1
NP_355997.2
NP_535143.1
Q7CVJ3  
 Arad_9538 (Agal2)   Agrobacterium radiobacter K84 ACM30558.1 B9JKW6  
 Arad_9545 (Agal1)   Agrobacterium radiobacter K84 ACM30563.1 B9JKX1  
 B0909_14205   Agrobacterium rhizogenes K599 AQS63539.1    
 B0909_14180   Agrobacterium rhizogenes K599 AQS63534.1    
 AGROH133_09638   Agrobacterium sp. H13-3 ADY65916.1    
 AGROH133_09618   Agrobacterium sp. H13-3 ADY65911.1    
 BSY240_3746   Agrobacterium sp. RAC06 AOG09386.1    
 At1D1609_48030 (MelA)   Agrobacterium tumefaciens 1D1609 AVH44844.1    
 At1D1609_47980 (MelA)   Agrobacterium tumefaciens 1D1609 AVH44839.1    
 Ach5_43890 (MelA)   Agrobacterium tumefaciens Ach5 AKC10162.1    
 Ach5_43840 (MelA)   Agrobacterium tumefaciens Ach5 AKC10157.1    
 X971_4578   Agrobacterium tumefaciens LBA4213 (Ach5) AHK04422.1    
 X971_4573   Agrobacterium tumefaciens LBA4213 (Ach5) AHK04417.1    
 AWN88_02375   Agrobacterium tumefaciens S33 AMD57121.1    
 AWN88_02400   Agrobacterium tumefaciens S33 AMD57126.1    
 Avi_5115 (MelA)   Agrobacterium vitis S4 ACM38294.1 B9K096  
 Avi_5121 (MelA)   Agrobacterium vitis S4 ACM38299.1 B9K0A1  
 ATC03_05525   Agromyces aureus AR33 ANJ26260.1    
 DCE93_10420   Agromyces sp. 30A AWB96023.1    
 α-galactosidase (aGly)   Alicyclobacillus acidocaldarius ABI81474.1 A6XNR3  
 Aaci_0797   Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV57840.1 C8WU77  
 VSAL_II1024   Aliivibrio salmonicida LFI1238 CAQ81778.1 B6EST0  
 Amet_4185   Alkaliphilus metalliredigens QYMF ABR50266.1 A6TVP8  
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