Glycoside Hydrolase Family 48

Activities in Familyreducing end-acting cellobiohydrolase (EC; endo-β-1,4-glucanase (EC; chitinase (EC
Mechanism Inverting
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
Noteformerly known as cellulase family L. Some cellobiohydrolases of this family have been reported to act from the reducing ends of cellulose (EC 3.2.1.-), while others have been reported to operate from the non-reducing ends to liberate cellobiose or cellotriose or cellotetraose (EC 3.2.1.-). This family also contains endo-processive cellulases (EC 3.2.1.-), whose activity is hard to distinguish from that of cellobiohydrolases.
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Commercial Enzyme Provider(s)NZYTech;
Statistics GenBank accession (1250); Uniprot accession (114); PDB accession (29); 3D entries (10); cryst (0)
All (1091) Bacteria (1049) Eukaryota (34) Viruses (2) unclassified (6) Structure (10) Characterized (20)
Protein Name EC#OrganismGenBank UniprotPDB/3D
 SARM_0053 / 1466158_16310 / TX-3 (fragment)   uncultured organism ADX05724.1    
 ORF   uncultured organism AGU11295.1    
 EKD16_23830 (CbhB)   Streptomonospora sp. M2 QBI56512.1    
 KTC_24370   Thermosporothrix sp. COM3 BBH87686.1    
 E5N77_30625   Streptomyces sp. SS52 QCB25684.1    
 E5225_01860   Cellulomonas sp. Z28 QCB92486.1    

Last update: 2019-06-06 © Copyright 1998-2019
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