Glycoside Hydrolase Family 47

Known Activities	α-mannosidase (EC 3.2.1.113)
Mechanism	Inverting
3D Structure Status	( α / α ) ₇
Catalytic Nucleophile/Base	Not known
Catalytic Proton Donor	Glu
External resources	ERManI Page; HOMSTRAD; InterPro; PFAM; PRINTS;
Statistics	GenBank accession (845); Uniprot accession (197); PDB accession (13); 3D entries (5); cryst (0)

Summary

All (343) Bacteria (6) Eukaryota (337) Structure (5 ) Characterized (29)

Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
α-mannosidase I (Man1B1;ERManI)	3.2.1.113	Homo sapiens	AAD45504.1 AAF03215.1 AAH02953.1 AAH06079.1 AAQ88830.1 ABA31377.1 ABA36377.1 ABA37959.1 ABA68636.1 ABA69639.1 ABA70021.1 ABA70144.1 ABC03965.1 ABC16000.1 ABE23455.1 ABE26018.1 ABE26291.1 ABH64528.1 ABH64651.1 ABH64808.1 ABH66037.1 ABH70856.1 ABH70979.1 ABH72493.1 ABH75608.1 ABH99393.1 ABI02498.1 ABI07299.1 ABI10947.1 ABI12149.1 ABJ19332.1 ABJ34327.1 ABJ43225.1 ABL21769.1 ABN29858.1 ABN30045.1 ABP27825.1 ABX93887.1 ABX96180.1 ABX96490.1 ABX96800.1 ABY04954.1 ABY18690.1 ACC17223.1 ACC32395.1 ACE08681.1 ACG89592.1 ACH31821.1 ACJ99887.1 ACK30491.1 ACM94998.1 ACM96778.1 ACN08779.1 ACP73753.1 ACS06379.1 ACS08553.1 ACW23746.1 BAC11060.1 BAD92513.1 BAG51987.1 BAG54653.1 BAG54664.1 BAG60691.1 BAG61117.1 CAB53680.2 CAC27261.1 CAF85799.1 CAF86770.1 CAH72871.2 CAH72887.1 CAI12781.1 NP_009161.1 NP_057303.1	Q8N2P4 Q9UFZ8 Q9UKM7.2	1FMI[A] 1FO2[A] 1FO3[A] 1X9D[A]
α-1,2-mannosidase (MDS1)	3.2.1.113	Hypocrea jecorina	AAF34579.1 CAY06025.1 CAY09785.1	Q9P8T8	1HCU[A,B,C,D]
mannosyl-oligosaccharide 1,2-α-mannosidase IA (ManA1;Man1A;Man1A1)	3.2.1.113	Mus musculus	AAA17747.1 AAH15265.1 BAC27225.1 BAE28536.1 BAE32852.1 CAH33904.1 CAH33939.1 CAH56918.1 CBA11298.1 CBA12843.1 CBA34883.1 NP_032574.1	P45700 Q544T7	1NXC[A]
α-1,2-mannosidase (MsdC)	3.2.1.113	Penicillium citrinum	BAA08275.1	P31723.2	1KKT[A,B] 1KRE[A,B] 1KRF[A,B] 2RI8[A,B] 2RI9[A,B]
α-mannosidase (Mns1;YJR131w;J2110) (ER)	3.2.1.113	Saccharomyces cerevisiae S288c	AAA34799.1 CAA89662.1 CAY05981.1 CAY09741.1 CAY09788.1 NP_012665.1	P32906.1	1DL2[A] 1G6I[A]