Glycoside Hydrolase Family 47

Activities in Familyα-mannosidase (EC 3.2.1.113)
Mechanism Inverting
3D Structure Status( α / α ) 7
Catalytic Nucleophile/BaseNot known
Catalytic Proton DonorGlu
External resourcesCAZypedia; HOMSTRAD; PRINTS;
Statistics GenBank accession (1525); Uniprot accession (225); PDB accession (22); 3D entries (6); cryst (0)
All (981) Bacteria (20) Eukaryota (961) Structure (6) Characterized (43)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Sequence 17210 from patent US 6747137   Candida albicans AAV05253.1    
 α-1,2-mannosidase (Mns1;CaMNS1) 3.2.1.113 Candida albicans ATCC 26555 AAN86059.2
AAO23958.1
Q875J2
Q8J0Q0
 
 CAALFM_C203910CA   Candida albicans SC5314 AOW27418.1    
 CAALFM_C103730CA (Mns1)   Candida albicans SC5314 AOW26050.1    
 unnamed protein product   Candida albicans SC5314 CAY09768.1
CAY06008.1
   
 unnamed protein product   Candida albicans SC5314 CAY33082.1
CAY38426.1
   
 CD36_03470   Candida dubliniensis CD36 CAX44607.1 B9W7E8  
 CD36_18550   Candida dubliniensis CD36 CAX43635.1 B9WB65  
 α-mannosidase MNS1 (fragment)   Candida dubliniensis T10 AAD39985.1 Q9Y8A9  
 CAGL0F01771g   Candida glabrata CBS 138 CAG58973.1 Q6FUP5  
 CAGL0F09053g   Candida glabrata CBS 138 CAY33077.1
CAG59285.1
   
 CAGL0M00528g   Candida glabrata CBS 138 CAY09759.1
CAG62344.1
   
 SAMEA4029010_CIC11G00000002148   [Candida] intermedia CBS 141442 SGZ54042.1    
 SAMEA4029010_CIC11G00000005289   [Candida] intermedia CBS 141442 SGZ47647.1    
 SAMEA4029009_CIC11G00000000410   [Candida] intermedia PYCC 4715 SGZ53844.1    
 SAMEA4029009_CIC11G00000001021   [Candida] intermedia PYCC 4715 SGZ49072.1    
 CORT_0A10670   Candida orthopsilosis Co 90-125 CCG21453.1    
 CORT_0B11480   Candida orthopsilosis Co 90-125 CCG22847.1    
 CPAR2_110370   Candida parapsilosis CDC317 CCE40999.1    
 CPAR2_211340   Candida parapsilosis CDC317 CCE43490.1    
 glycosyl hydrolase family 47 domain-containing protein, partial (Gh47) (fragment)   Chikusichloa aquatica AIY26408.1    
 type II membrane protein of ER-like (fragment)   Ciona intestinalis AAP91746.1 Q69HN5  
 α-mannosidase 1 (Amn1)   Coccidioides posadasii C735 ABA54911.1 Q3HYC1  
 α-1,2-mannosidase 3.2.1.113 Coccidioides posadasii Silveira ABB36773.3
ABB36773.2
Q3HYC1  
 A9K55_006197   Cordyceps militaris ATCC 34164 ATY59985.1    
 A9K55_008982   Cordyceps militaris ATCC 34164 ATY62020.1    
 A9K55_007512   Cordyceps militaris ATCC 34164 ATY62742.1    
 A9K55_004092   Cordyceps militaris ATCC 34164 ATY65106.1    
 A9K55_005237   Cordyceps militaris ATCC 34164 ATY64924.1    
 A9K55_006052   Cordyceps militaris ATCC 34164 ATY60662.1    
 ER degradation enhancing α-mannosidase-like protein   Cricetulus griseus BAF75842.1 A7M771  
 ORF   Crotalus adamanteus AFJ50004.1    
 ORF   Crotalus adamanteus AFJ50541.1    
 ORF   Cryptococcus depauperatus CBS7855 ACZ80670.1 D2JWW7  
 CGB_E6120W   Cryptococcus gattii WM276 ADV22676.1    
 CGB_G2060C   Cryptococcus gattii WM276 ADV23425.1    
 CGB_K0370C (fragment)   Cryptococcus gattii WM276 ADV24786.1    
 CNAG_02081   Cryptococcus neoformans var. grubii H99 AFR95738.1    
 CNAG_03240   Cryptococcus neoformans var. grubii H99 AFR96466.1
AFR96466.2
   
 CNAG_01987   Cryptococcus neoformans var. grubii H99 AFR98181.1    
 CKF44_002885   Cryptococcus neoformans var. grubii KN99 AUB26389.1    
 CKF44_001778   Cryptococcus neoformans var. grubii KN99 AUB28289.1    
 CKF44_001866   Cryptococcus neoformans var. grubii KN99 AUB25576.1    
 unnamed protein product   Cryptococcus neoformans var. neoformans B-3501A CAY09771.1
CAY06011.1
   
 unnamed protein product   Cryptococcus neoformans var. neoformans B-3501A CAY09772.1
CAY06012.1
   
 CNE04550   Cryptococcus neoformans var. neoformans JEC21 AAW43838.1 Q5KG79  
 CNG03330   Cryptococcus neoformans var. neoformans JEC21 AAW44752.1 Q5KDN4  
 CNK03190   Cryptococcus neoformans var. neoformans JEC21 AAW46395.2
AAW46395.1
Q5K950  
 CYME_CMF045C   Cyanidioschyzon merolae strain 10D BAM79428.1    
 CYFA0S_02e10088g   Cyberlindnera fabianii YJS4271 CDR38987.1    
 CYFA0S_16e02520g   Cyberlindnera fabianii YJS4271 CDR45131.1    
 CYFA0S_24e00540g   Cyberlindnera fabianii YJS4271 CDR46585.1    
 ORF   Danio rerio AAH45461.1
AAI65707.1
NP_957483.1
Q7ZVP7  
 ORF   Danio rerio AAH45854.1 Q7ZVI0  
 ORF   Danio rerio AAH55547.1 Q7SXL5  
 DKEY-164K19.1-001   Danio rerio CAI20711.2
CAI20711.1
CAI21344.1
CAI21344.2
CAN88497.1
Q5RHM7  
 DKEY-61L1.3-001   Danio rerio CAN88131.1 A5WWD5  
 DKEY-150D12.6-001 (probable fragment)   Danio rerio CAP19482.1 A9C3P7  
 DKEY-174K18.8-001   Danio rerio CAQ15342.1 B0V2X9  
 DEHA0D07667g (DEHA2D06930g)   Debaryomyces hansenii CBS767 CAG86907.1
CAR65626.1
CAY06001.1
CAY09761.1
CAY33080.1
CAY38425.1
   
 DEHA0D10153g   Debaryomyces hansenii CBS767 CAY09762.1
CAG87017.1
CAY06002.1
   
 dd_03122   Dictyostelium discoideum AX4 AAM33693.1
AAO52054.2
AAO52627.1
   
 146015 (fragment)   Drosophila americana ABL85362.1
ABL85363.1
ABL85364.1
ABL85365.1
ABL85366.1
ABL85367.1
ABL85368.1
ABL85369.1
ABL85370.1
ABL85371.1
ABL85372.1
ABL85373.1
ABL85374.1
ABL85375.1
ABL85376.1
ABL85377.1
ABL85378.1
ABL85379.1
ABL85380.1
ABL85381.1
ABL85382.1
ABL85383.1
ABL85384.1
ABL85385.1
ABL85386.1
ABL85387.1
ABL85388.1
ABL85389.1
ABL85390.1
ABL85391.1
ABL85392.1
ABL85393.1
ABL85394.1
ABL85395.1
ABL85396.1
ABL85397.1
ABL85398.1
ABL85399.1
ABL85400.1
ABL85401.1
A1YU71  
 Dbus_chr2Lg425   Drosophila busckii ALC38340.1    
 Dbus_chr3Rg948   Drosophila busckii ALC46198.1    
 Dbus_chrXg1257   Drosophila busckii ALC49401.1    
 Dbus_chrXg1305   Drosophila busckii ALC49449.1    
 α-1,2-mannosidase I (Mas-1;Mas1;Dmel_CG42275) 3.2.1.113 Drosophila melanogaster AAF46570.1
AAR30196.1
AAS65302.1
AAS65303.1
AAS65304.1
AAS65305.1
AAS65306.1
CAA57962.1
NP_727407.1
NP_996395.1
NP_996396.1
NP_996397.1
NP_996398.1
NP_996399.1
P53624  
 α-mannosidase 2 (α-Man-1;Mas-1;Dmel_CG32684) 3.2.1.113 Drosophila melanogaster CAA57963.1
AAF46571.3
AGB95245.1
NP_511105.2
P53625
P53625
 
 EDEM1 (EG:86E4.2;CG3810; Dmel_CG3810)   Drosophila melanogaster CAA15933.1
AAF45690.1
AAF45691.1
AAF45692.1
AAM50254.1
AAM75015.1
ACV53079.1
AFH07197.1
AGB94998.1
NP_569959.1
NP_726777.1
NP_726778.1
O46091
Q9W544
 
 CG11874   Drosophila melanogaster AAF56854.1
AAL14004.1
NP_651667.1
Q9VAP8  
 CG31202   Drosophila melanogaster AAN14202.1
AAF56975.1
AAY54628.1
NP_733331.1
Q8IMK0  
 EDEM2 (CG5682;Dmel_CG5682)   Drosophila melanogaster AAF53255.2
AAM50976.1
ACL68693.1
AGB92969.1
NP_609611.1
Q8MS36
Q9VK27
 
 ORF (fragment)   Equus caballus AEP99199.1    
 ORF (fragment)   Equus caballus AEP99235.1    
 ORF (fragment)   Equus caballus AEP99778.1    
 ORF (fragment)   Equus caballus AEQ00044.1    
 Ecym_1503   Eremothecium cymbalariae DBVPG#7215 AET37727.1    
 Ecym_5170   Eremothecium cymbalariae DBVPG#7215 AET39944.1    
 AER165W   Eremothecium gossypii ATCC 10895 AAS52847.1 Q756T8  
 ADL390W   Eremothecium gossypii ATCC 10895 AAS51530.1
AAS51530.2
Q75BF4  
 ACR213W   Eremothecium gossypii ATCC 10895 AAS51439.1 Q75BQ8  
 FAGOS_FACR213W   Eremothecium gossypii FDAG1 AEY95730.1    
 FAGOS_FADL390W   Eremothecium gossypii FDAG1 AEY95826.1    
 FAGOS_FAER165W   Eremothecium gossypii FDAG1 AEY97154.1    
 AW171_hschr74005   Eremothecium sinecaudum ATCC 58844 AMD22002.1    
 AW171_hschr74112   Eremothecium sinecaudum ATCC 58844 AMD22101.1    
 AW171_hschr42101   Eremothecium sinecaudum ATCC 58844 AMD20217.1    
 mannosyl-oligosaccharide 1,2-α-mannosidase, partial (fragment)   Fargesia nitida AHN93249.1    
 mannosyl-oligosaccharide 1,2-α-mannosidase, partial (fragment)   Fargesia nitida AHN93250.1    
 mannosyl-oligosaccharide 1,2-α-mannosidase, partial (fragment)   Fargesia spathacea AHN93251.1    
 mannosyl-oligosaccharide 1,2-α-mannosidase, partial (fragment)   Fargesia spathacea AHN93252.1    
 FFUJ_01918   Fusarium fujikuroi IMI 58289 CCT61595.1    
 FFUJ_01136   Fusarium fujikuroi IMI 58289 CCT62324.1    
 FFUJ_00589   Fusarium fujikuroi IMI 58289 CCT62821.1    
 FFUJ_13542   Fusarium fujikuroi IMI 58289 CCT67337.1    
 FFUJ_07532   Fusarium fujikuroi IMI 58289 CCT68723.1    
 FFUJ_12208   Fusarium fujikuroi IMI 58289 CCT72349.1    
 FFUJ_09343   Fusarium fujikuroi IMI 58289 CCT73833.1    
 FFUJ_09184   Fusarium fujikuroi IMI 58289 CCT73980.1    
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